Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tobias Hasenberg"'
Autor:
Anja Patricia Ramme, Leopold Koenig, Tobias Hasenberg, Christine Schwenk, Corinna Magauer, Daniel Faust, Alexandra K Lorenz, Anna-Catharina Krebs, Christopher Drewell, Kerstin Schirrmann, Alexandra Vladetic, Grace-Chiaen Lin, Stephan Pabinger, Winfried Neuhaus, Frederic Bois, Roland Lauster, Uwe Marx, Eva-Maria Dehne
Publikováno v:
Future Science OA, Vol 5, Iss 8 (2019)
Microphysiological systems play a pivotal role in progressing toward a global paradigm shift in drug development. Here, we designed a four-organ-chip interconnecting miniaturized human intestine, liver, brain and kidney equivalents. All four organ mo
Externí odkaz:
https://doaj.org/article/8b4907e94de7419ea2fc0f71c05acb8f
Autor:
Tobias Hasenberg
Publikováno v:
geschichte für heute. 13:7-20
Autor:
Tobias Hasenberg
Publikováno v:
Zeitschrift für Geschichtsdidaktik. 17:87-100
Autor:
Anja Patricia Ramme, Uwe Marx, Alexandra Vladetic, Grace-Chiaen Lin, Christine Schwenk, Roland Lauster, Kerstin Schirrmann, Leopold Koenig, Christopher Drewell, Anna-Catharina Krebs, Winfried Neuhaus, Stephan Pabinger, Tobias Hasenberg, Corinna Magauer, Eva-Maria Dehne, Frédéric Y. Bois, Alexandra Lorenz, Daniel Faust
Microphysiological systems are fundamental for progressing towards a global paradigm shift in drug development through the generation of patient-on-a-chip models. An increasing number of single- and multi-organ systems have been adopted by the pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43bce61eea3cc72e40489784072de53
https://doi.org/10.1101/376970
https://doi.org/10.1101/376970
Autor:
Kerstin Schirrmann, Marian Raschke, Uwe Marx, Alexandra Lorenz, Juliane Hübner, Sarah Gräßle, Tobias Hasenberg, Roland Lauster, Thomas Steger-Hartmann, Susanne Schnurre, Isabel Rütschle, Ilka Maschmeyer
Publikováno v:
Hübner, J, Raschke, M, Rütschle, I, Gräßle, S, Hasenberg, T, Schirrmann, K, Lorenz, A, Schnurre, S, Lauster, R, Maschmeyer, I, Steger-Hartmann, T & Marx, U 2018, ' Simultaneous evaluation of anti-EGFR-induced tumour and adverse skin effects in a microfluidic human 3D co-culture model ', Scientific Reports, vol. 8, no. 1, pp. 15010 . https://doi.org/10.1038/s41598-018-33462-3
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Antibody therapies targeting the epithelial growth factor receptor (EGFR) are being increasingly applied in cancer therapy. However, increased tumour containment correlates proportionally with the severity of well-known adverse events in skin. The pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd832de174861c9935521d080ffc3303
https://www.research.manchester.ac.uk/portal/en/publications/simultaneous-evaluation-of-antiegfrinduced-tumour-and-adverse-skin-effects-in-a-microfluidic-human-3d-coculture-model(f75273f7-e8ab-4945-81f0-aa9a72b7f31f).html
https://www.research.manchester.ac.uk/portal/en/publications/simultaneous-evaluation-of-antiegfrinduced-tumour-and-adverse-skin-effects-in-a-microfluidic-human-3d-coculture-model(f75273f7-e8ab-4945-81f0-aa9a72b7f31f).html
Autor:
Severin Mühleder, Uwe Marx, Lea Knezevic, Tobias Hasenberg, Wolfgang Holnthoner, Heinz Redl, Mira Schaupper, Katharina Schimek, Eleni Priglinger
Publikováno v:
Frontiers in Bioengineering and Biotechnology
Vascular network engineering is essential for nutrient delivery to tissue-engineered constructs and, consequently, their survival. In addition, the functionality of tissues also depends on tissue drainage and immune cell accessibility, which are the
Publikováno v:
BIOspektrum. 23:301-302
New regulations and novel substance classes made the evaluation and authorisation process of drugs, cosmetics and chemicals not only more complicated but laborious. A microphysiological system was developed as a new foundation for substance discovery
Autor:
Roland Lauster, Tobias Hasenberg, Severin Mühleder, Wolfgang Holnthoner, Krystyna Labuda, Andrea Dotzler, Uwe Marx, Heinz Redl, Sophie Bauer
Publikováno v:
Journal of biotechnology. 216
Current microfluidic chip-based tissue culture systems lack a capillary endothelial vessel system, which would enable perfusion with blood. We utilise spatial cell cultures to populate a perfused multi-organ-chip platform-a microfluidic device recent
Autor:
Uwe Marx, Alexandra Lorenz, Juliane Hübner, Ilka Maschmeyer, Tobias Hasenberg, Roland Lauster, Anja Patricia Ramme, Katharina Schimek, Naomia Sisoli Sambo, Christopher Drewell, Sophie Bauer, Alexander Thomas, Frank Sonntag, Marcus Lindner
Systemic absorption and metabolism of drugs in the small intestine, metabolism by the liver as well as excretion by the kidney are key determinants of efficacy and safety for therapeutic candidates. However, these systemic responses of applied substa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb717f67e7709903aa80597d02b5fd83
Autor:
Reyk Horland, Alexandra Lorenz, M. Dehne, Ilka Maschmeyer, Juliane Hübner, Uwe Marx, Annika Jaenicke, Anja Patricia Ramme, Katharina Schimek, Roland Lauster, Tobias Hasenberg, B. Atac-Wagegg
Publikováno v:
Toxicology Letters. 259:S9-S10