Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tobias Hadlich"'
Autor:
Monika Gothwal, Alessandro Rambaldi, Brigitte Schlegelberger, Kien Binh Pham, Britta Will, Jonas S. Jutzi, Kai B. Kaufmann, Albert Gründer, Julia M. Wagner, Doris Steinemann, Thomas Günther, Manfred Jung, Konrad Aumann, Thalia S. Seeger, Tobias Hadlich, Julius Wehrle, Roland Schüle, Lucas Ganzenmüller, Sarah Kayser, Ulrich Steidl, Martin Werner, Heike L. Pahl, Ruzhica Bogeska
Publikováno v:
The Journal of Experimental Medicine
Mice expressing a transgene encoding the transcription factor NF-E2 in hematopoietic cells exhibit features of myeloproliferative neoplasms, including thrombocytosis, Epo-independent colony formation, stem and progenitor cell overabundance, leukocyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4065c0eeb34d9a8a1c9fb87750ee01e
https://doi.org/10.1084/jem.20110540
https://doi.org/10.1084/jem.20110540
Autor:
Mascha Binder, Nicolaus Kroeger, Isabel Ben-Batalla, Andreas Hochhaus, Gunhild von Amsberg, David Micklem, Tim H. Brümmendorf, Heather Morrison, Victoria Gensch, Philippe Schafhausen, Alexander Schultze, Steffen Koschmieder, Sonja Loges, Miguel Cubas-Cordova, Tobias Hadlich, Melanie Janning, Carsten Bokemeyer, Richard E. Clark, James B. Lorens, Peter Vandenberghe, Mark Wroblewski, Robert Erdmann, Heather G. Jørgensen, Jennifer Cassells, Elaine K. Allan, Tessa L. Holyoake, Klaus Pantel, Nils Kruse, Peter Carmeliet, Stefanie Sawall, Leena Mukherjee
Publikováno v:
Blood. 124:4512-4512
BCR-ABL1 inhibitors have revolutionized the treatment of CML patients. However several drawbacks remain, including clinical resistance of T315I-mutated CML. Further, the clinical success of ponatinib, a selective inhibitor of T315I-mutated BCR-ABL1 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17dce326042db781d2b5b48274d3f6ac
https://doi.org/10.1182/blood.v124.21.4512.4512
https://doi.org/10.1182/blood.v124.21.4512.4512
Autor:
Kai B. Kaufmann, Annette Schmitt-Graeff, Heike L. Pahl, Thomas Günther, Roland Schüle, Tobias Hadlich, Attilio Orazi, Albert Gruender
Publikováno v:
Blood. 114:961-961
Abstract 961 The transcription factor nuclear factor erythroid-2 (NF-E2) is expressed in hematopoietic stem cells as well as in myeloid, erythroid and megakaryocytic precursors. NF-E2 deficient mice display marked anemia at birth and die perinatally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11bb5dd567ef9457ffe7da18fe007ae5
https://doi.org/10.1182/blood.v114.22.961.961
https://doi.org/10.1182/blood.v114.22.961.961