Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tobias Fleige"'
Autor:
Katharina Hohenfellner, Carsten Bergmann, Tobias Fleige, Nils Janzen, Siegfried Burggraf, Bernd Olgemöller, William A. Gahl, Ludwig Czibere, Sonja Froschauer, Wulf Röschinger, Katharina Vill, Erik Harms, Uta Nennstiel
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 21, Iss , Pp - (2019)
Background: Newborn screening (NBS) programs for treatable metabolic disorders have been enormously successful, but molecular-based screening has not been broadly implemented so far. Methods: This prospective pilot study was performed within the Germ
Externí odkaz:
https://doaj.org/article/7b81688622b649f0976083200101c04d
Autor:
Siegfried Burggraf, Jürgen Durner, Katharina Hohenfellner, Lisa Marie Keitel, Tobias Fleige, Marc Becker, Julia Häring, Erik Harms, Wulf Röschinger, Olfert Landt, Ludwig Czibere, Birgit Glück
Publikováno v:
Eur J Hum Genet
Nephropathic cystinosis is a rare autosomal recessive lysosomal storage disorder, which causes loss of renal proximal tubular function and progressive loss of glomerular function, finally leading to end stage renal failure at school age. In the cours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219f4bc6791a01517212b3e9f8866da8
https://doi.org/10.1038/s41431-019-0521-3
https://doi.org/10.1038/s41431-019-0521-3
Autor:
Jürgen Durner, Ludwig Czibere, Katharina Hohenfellner, Katharina Vill, Marc Becker, Olfert Landt, Siegfried Burggraf, Tobias Fleige, Wolfgang Müller-Felber, Birgit Glück, Wulf Röschinger, Brunhilde Wirth, Lisa Marie Keitel
Publikováno v:
Eur J Hum Genet
Establishing nucleic acid-based assays for genetic newborn screening (NBS) provides the possibility to screen for genetically encoded diseases like spinal muscular atrophy (SMA), best before the onset of symptoms. Such assays should be easily scalabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334586944be359bba309abf0d7f180b2
https://doi.org/10.1038/s41431-019-0476-4
https://doi.org/10.1038/s41431-019-0476-4
Autor:
Siegfried Burggraf, Marc Becker, Jürgen Durner, Arleta Madejska, David C. Watts, Frank Krieg-Schneider, Tobias Fleige, Ludwig Czibere
Publikováno v:
Dental Materials
Durner, J, Burggraf, S, Czibere, L, Fleige, T, Madejska, A, WATTS, D C, Kreig-Schneider, F & Becker, M 2020, ' Fast and simple high-throughput testing of COVID 19 ', Dental Materials . https://doi.org/10.1016/j.dental.2020.04.001
Durner, J, Burggraf, S, Czibere, L, Fleige, T, Madejska, A, WATTS, D C, Kreig-Schneider, F & Becker, M 2020, ' Fast and simple high-throughput testing of COVID 19 ', Dental Materials . https://doi.org/10.1016/j.dental.2020.04.001
A rapid and easily workable alternative (MEP: Munich Extraction Protocol) is outlined to our current RNA purification method for circumstances where there is limited availability of test kits. Details are available upon request.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01969f2c98028aaa84de97268902e2d2
Publikováno v:
Microbes and Infection. 12:253-262
Most Apicomplexans possess a relic plastid named apicoplast, originating from secondary endosymbiosis of a red algae. This non-photosynthetic organelle fulfils important metabolic functions and confers sensitivity to antibiotics. The tasks of this or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df0a98cc6b9a962daf576ca4695c158
https://doi.org/10.1016/j.micinf.2009.12.010
https://doi.org/10.1016/j.micinf.2009.12.010
Publikováno v:
International Journal for Parasitology. 38:1121-1132
The apicomplexan parasite Toxoplasma gondii displays some unusual localisations of carbohydrate converting enzymes, which is due to the presence of a vestigial, non-photosynthetic plastid, referred to as the apicoplast. It was recently demonstrated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfbc4fed02c8748867eb27660d8d928
https://doi.org/10.1016/j.ijpara.2008.01.007
https://doi.org/10.1016/j.ijpara.2008.01.007
Autor:
Richard Lucius, Scott M. Landfear, Tobias Fleige, Martin Blume, Dominique Soldati-Favre, Nishith Gupta, Dayana Rodriguez-Contreras
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 106, No 31 (2009) pp. 12998-3003
Toxoplasma gondii , as an obligate intracellular and promiscuous pathogen of mammalian cells, utilizes host sugars for energy and to generate glycoconjugates that are important to its survival and virulence. Here, we report that T. gondii glucose tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9703cee4bcf57a02f5848460e84a8df
https://archive-ouverte.unige.ch/unige:3975
https://archive-ouverte.unige.ch/unige:3975
Autor:
Tobias Fleige, Dominique Soldati-Favre
Publikováno v:
Current drug targets, Vol. 9, No 11 (2008) pp. 948-56
Apicomplexans are obligate intracellular parasites causing devastating disease in both humans and livestock. Nearly all apicomplexans, with the exception of Cryptosporidium, contain two endosymbiontic organelles carrying their own DNA; the mitochondr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5effc036a5dbf1f0858dde7e33756461
https://archive-ouverte.unige.ch/unige:2233
https://archive-ouverte.unige.ch/unige:2233
Publikováno v:
Molecular and biochemical parasitology. 157(2)
By using suppression subtractive hybridization we identified five so far uncharacterized stage specific genes in Toxoplasma gondii, which are induced during tachyzoite-to-bradyzoite differentiation. The mRNA level of a putative zinc-finger protein wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b2b9e41c6dd79016716646f9538992
https://pubmed.ncbi.nlm.nih.gov/18061287
https://pubmed.ncbi.nlm.nih.gov/18061287
Publikováno v:
Eukaryotic cell. 6(6)
Many apicomplexan parasites, such as Toxoplasma gondii and Plasmodium species, possess a nonphotosynthetic plastid, referred to as the apicoplast, which is essential for the parasites’ viability and displays characteristics similar to those of nong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b6429cc52a5a236d42ec0e83774479
https://pubmed.ncbi.nlm.nih.gov/17449654
https://pubmed.ncbi.nlm.nih.gov/17449654