Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Tobias Beck"'
Autor:
Patrick Y. A. Reinke, Robin Schubert, Dominik Oberthür, Marina Galchenkova, Aida Rahmani Mashhour, Sebastian Günther, Anaïs Chretien, Adam Round, Brandon Charles Seychell, Brenna Norton-Baker, Chan Kim, Christina Schmidt, Faisal H. M. Koua, Alexandra Tolstikova, Wiebke Ewert, Gisel Esperanza Peña Murillo, Grant Mills, Henry Kirkwood, Hévila Brognaro, Huijong Han, Jayanath Koliyadu, Joachim Schulz, Johan Bielecki, Julia Lieske, Julia Maracke, Juraj Knoska, Kristina Lorenzen, Lea Brings, Marcin Sikorski, Marco Kloos, Mohammad Vakili, Patrik Vagovic, Philipp Middendorf, Raphael de Wijn, Richard Bean, Romain Letrun, Seonghyun Han, Sven Falke, Tian Geng, Tokushi Sato, Vasundara Srinivasan, Yoonhee Kim, Oleksandr M. Yefanov, Luca Gelisio, Tobias Beck, Andrew S. Doré, Adrian P. Mancuso, Christian Betzel, Saša Bajt, Lars Redecke, Henry N. Chapman, Alke Meents, Dušan Turk, Winfried Hinrichs, Thomas J. Lane
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The main protease (Mpro) of SARS-CoV-2 is critical for viral function and a key drug target. Mpro is only active when reduced; turnover ceases upon oxidation but is restored by re-reduction. This suggests the system has evolved to survive pe
Externí odkaz:
https://doaj.org/article/7a737b71ae764265a7f11a3df650ea0b
Autor:
Patrick Y. A. Reinke, Edmarcia Elisa de Souza, Sebastian Günther, Sven Falke, Julia Lieske, Wiebke Ewert, Jure Loboda, Alexander Herrmann, Aida Rahmani Mashhour, Katarina Karničar, Aleksandra Usenik, Nataša Lindič, Andreja Sekirnik, Viviane Fongaro Botosso, Gláucia Maria Machado Santelli, Josana Kapronezai, Marcelo Valdemir de Araújo, Taiana Tainá Silva-Pereira, Antônio Francisco de Souza Filho, Mariana Silva Tavares, Lizdany Flórez-Álvarez, Danielle Bruna Leal de Oliveira, Edison Luiz Durigon, Paula Roberta Giaretta, Marcos Bryan Heinemann, Maurice Hauser, Brandon Seychell, Hendrik Böhler, Wioletta Rut, Marcin Drag, Tobias Beck, Russell Cox, Henry N. Chapman, Christian Betzel, Wolfgang Brehm, Winfried Hinrichs, Gregor Ebert, Sharissa L. Latham, Ana Marcia de Sá Guimarães, Dusan Turk, Carsten Wrenger, Alke Meents
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Several drug screening campaigns identified Calpeptin as a drug candidate against SARS-CoV-2. Initially reported to target the viral main protease (Mpro), its moderate activity in Mpro inhibition assays hints at a second target. Indeed, we s
Externí odkaz:
https://doaj.org/article/959ee7d783844cc0965882267049dc4f
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e22039- (2023)
The determination of the drying degree of food residues on surfaces is an important step before efficient cleaning can be achieved. To accomplish this goal, a rapid evaluation based on a neural network and non-invasive measurement technique is introd
Externí odkaz:
https://doaj.org/article/16381fdd6a604aefb6e7fd1fb845d45f
Autor:
Brandon Charles Seychell, Tobias Beck
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 1-10 (2021)
This minireview provides an overview on the current knowledge of protein–protein interactions, common characterisation methods to characterise them, and their role in protein complex formation with some examples. A deep understanding of protein–p
Externí odkaz:
https://doaj.org/article/f6158ff1c5804e3391327b6b0952a1b9
Autor:
Kun Luan, Andre J. West, Marian G. McCord, Emiel A. DenHartog, Quan Shi, Isa Bettermann, Jiayin Li, Nicholas V. Travanty, Robert D. Mitchell, Grayson L. Cave, John B. Strider, Yongxin Wang, Florian Neumann, Tobias Beck, Charles S. Apperson, R. Michael Roe
Publikováno v:
Insects, Vol 12, Iss 7, p 636 (2021)
Garments treated with chemical insecticides are commonly used to prevent mosquito bites. Resistance to insecticides, however, is threatening the efficacy of this technology, and people are increasingly concerned about the potential health impacts of
Externí odkaz:
https://doaj.org/article/980912b794bd4835851faa9b42420151
Publikováno v:
Applied Sciences, Vol 11, Iss 6, p 2655 (2021)
The transition of the powertrain from combustion to electric systems increases the demand for reliable copper connections. For such applications, laser welding has become a key technology. Due to the complexity of laser welding, especially at micro w
Externí odkaz:
https://doaj.org/article/1dc4ad987f7e4d2180ee14f3b331e65d
Autor:
Marieke Sternkopf, Sven Thoröe-Boveleth, Tobias Beck, Kirsten Oleschko, Ansgar Erlenkötter, Ulrich Tschulena, Sonja Steppan, Thimoteus Speer, Claudia Goettsch, Vera Jankowski, Joachim Jankowski, Heidi Noels, The European Uremic Toxin Work Group-EUTox
Publikováno v:
Toxins, Vol 11, Iss 7, p 389 (2019)
Hydrophobic uremic toxins accumulate in patients with chronic kidney disease, contributing to a highly increased cardiovascular risk. The clearance of these uremic toxins using current hemodialysis techniques is limited due to their hydrophobicity an
Externí odkaz:
https://doaj.org/article/e2209542c1be44838643e37cae2a420e
Autor:
Oskar Aurelius, Renzo Johansson, Viktoria Bågenholm, Daniel Lundin, Fredrik Tholander, Alexander Balhuizen, Tobias Beck, Margareta Sahlin, Britt-Marie Sjöberg, Etienne Mulliez, Derek T Logan
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0128199 (2015)
Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to deoxyribonucleotides, the building blocks for DNA synthesis, and are found in all but a few organisms. RNRs use radical chemistry to catalyze the reduction reaction. Despit
Externí odkaz:
https://doaj.org/article/7576ecbdbb304b1e84d79bde2069167f
Autor:
Tobias Beck, George M. Sheldrick
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 7, Pp o1286-o1286 (2008)
The title compound, C8H4I3NO4·H2O, shows an extensive hydrogen-bond network; in the crystal structure, molecules are linked by O—H...O, N—H...O and O—H...N hydrogen bonds involving all possible donors and also the water molecule.
Externí odkaz:
https://doaj.org/article/0b4ff99f715f4633aa0fc57f8d4425c8
Autor:
Patrick Reinke, Edmarcia de Souza, Sebastian Günther, Sven Falke, Julia Lieske, Wiebke Ewert, Jure Loboda, Alexander Herrmann, Aida Rahmani Mashhour, Katarina Karnicar, Aleksandra Usenik, Natasa Lindic, Andreja Sekirnik, Viviane Botosso, Gláucia Machado Santelli, Josana Kapronezai, Marcelo de Araújo, Taiana Silva-Pereira, Antonio Souza Filho, Mariana Tavares, Lizdany Flórez-Álvarez, Danielle Oliveira, Edison Durigon, Paula Giaretta, Marcos Heinemann, Maurice Hauser, Brandon Seychell, Hendrik Böhler, Wioletta Rut, Marcin Drag, Tobias Beck, Russell Cox, Henry Chapman, Christian Betzel, Wolfgang Brehm, Winfried Hinrichs, Gregor Ebert, Sharissa Latham, Ana Marcia Guimarães, Dušan Turk, Carsten Wrenger, Alke Meents
Several drug screening campaigns identified Calpeptin as a drug candidate against SARS-CoV-2. Initially reported to target the viral main protease (Mpro), its moderate activity in Mpro inhibition assays hints at a second target. Indeed, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a39214aa65c5a9ef54c73b10a0e72cbe
https://doi.org/10.21203/rs.3.rs-2450926/v1
https://doi.org/10.21203/rs.3.rs-2450926/v1