Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tobias Becherer"'
Publikováno v:
Sensors and Actuators B: Chemical. 223:400-405
Methylated dendritic polyglycerol (dPG(OMe)) is proposed as an antifouling coating for the application with silicon on insulator (SOI) bio sensors. Sensors were coated with dPG(OMe). Fibrinogen was used to test the antifouling properties. Using SOI r
Publikováno v:
Acta Biomaterialia. 25:43-55
Scaffold-free cell sheet engineering using thermoresponsive substrates provides a promising alternative to conventional tissue engineering which in general employs biodegradable scaffold materials. We have previously developed a thermoresponsive coat
Autor:
Ingo Grunwald, Tobias Becherer, Julian Sindram, Paul-Ludwig Michael Noeske, Rainer Haag, Matheus Vieira Nascimento, Qiang Wei
Publikováno v:
Progress in Organic Coatings. 87:146-154
This work describes the fabrication and evaluation of a transparent hydrogel based spray coating to reduce marine biofouling on glass surfaces. A glycerol based copolymer was synthesized and covalently immobilized by applying a simple spray coating p
Autor:
Tobias Becherer, Andreas Hartwig, Florian Paulus, Thorsten Hugel, Hendrik Liebe, Ingo Grunwald, Rainer Haag, Katharina Achazi, Paul-Ludwig Michael Noeske, Qiang Wei, Stefanie Krysiak, Jens Dernedde
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 122:684-692
A set of new catecholic monolayer coatings was developed to improve the antifouling performance of TiO2 surfaces. To solve the problem of the weak charge-transfer interaction between a single catechol anchor and TiO2, multiple catechol groups were co
Autor:
Rainer Haag, Tobias Becherer, Joachim Dzubiella, Axel T. Neffe, Christian Wischke, Stefano Angioletti-Uberti, Andreas Lendlein, Matthias Ballauff, Qiang Wei
Publikováno v:
Angewandte Chemie. 126:8138-8169
Die Proteinadsorption gilt als der wichtigste Faktor der Wechselwirkung zwischen polymeren Biomaterialien und Korperflussigkeiten oder -gewebe. Die Haupteinflussfaktoren auf die Proteinadsorption sind wasservermittelte hydrophobe und Hydratationskraf
Autor:
Ingo Grunwald, Tobias Becherer, Paul-Ludwig Michael Noeske, Rainer Haag, Radu-Cristian Mutihac, Florian Paulus, Qiang Wei
Publikováno v:
Biomacromolecules. 15:3061-3071
In this work, we combine nature's amazing bioadhesive catechol with the excellent bioinert synthetic macromolecule hyperbranched polyglycerol (hPG) to prepare antifouling surfaces. hPG can be functionalized by different amounts of catechol groups for
Autor:
Axel T. Neffe, Tobias Becherer, Karola Lützow, S. Braune, Friedrich Jung, Andreas Lendlein, Klaus Richau, Toralf Roch, Maik von Ruesten-Lange, Anne Krüger, Rainer Haag, Andreas F. Thünemann
Publikováno v:
Neffe, A.T.; Ruesten-Lange, M.v.; Braune, S.; Luetzow, K.; Roch, T.; Richau, K.; Krueger, A.; Becherer, T.; Thuenemann, A.F.; Jung, F.; Haag, R.; Lendlein, A.: Multivalent grafting of hyperbranched oligo-and polyglycerols shielding rough membranes to mediate hemocompatibility. In: Journal of Materials Chemistry B. Vol. 2 (2014) 23, 3626-3635. (DOI: 10.1039/C4TB00184B)
Hemocompatible materials are needed for internal and extracorporeal biomedical applications, which should be realizable by reducing protein and thrombocyte adhesion to such materials. Polyethers have been demonstrated to be highly efficient in this r
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 85:756-764
Proteins are surface active molecules which undergo non-specific adsorption when getting in contact with surfaces such as the primary packaging material. This process is critical as it may cause a loss of protein content or protein aggregation. To pr
Publikováno v:
Biomacromolecules, 12, 11, pp. 4169-4172
Biomacromolecules, 12, 4169-4172
Biomacromolecules, 12, 4169-4172
Polymer brushes show great promise in next-generation antibiofouling surfaces. Here, we have studied the influence of polymer brush architecture on protein resistance. By carefully optimizing reaction conditions, we were able to polymerize oligoglyce
Autor:
Marie Weinhart, Rainer Haag, Tobias Becherer, Hans-Jörg Kunte, Nicolai Schnurbusch, Karin Schwibbert
Publikováno v:
Advanced Engineering Materials. 13:B501-B510
The non-specific adsorption of proteins to surfaces in contact with biofluids constitutes a major problem in the biomedical and biotechnological field, due to the initiation of biofilm formation and the resulting improper function of devices. Therefo