Zobrazeno 1 - 10
of 404
pro vyhledávání: '"Tobias B, Huber"'
Autor:
Ola Al-Diab, Christin Sünkel, Eric Blanc, Rusan Ali Catar, Muhammad Imtiaz Ashraf, Hongfan Zhao, Pinchao Wang, Markus M. Rinschen, Raphaela Fritsche-Guenther, Florian Grahammer, Sebastian Bachmann, Dieter Beule, Jennifer A. Kirwan, Nikolaus Rajewsky, Tobias B. Huber, Dennis Gürgen, Angelika Kusch
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Background Sex differences exist in the prevalence and progression of major glomerular diseases. Podocytes are the essential cell-type in the kidney which maintain the physiological blood-urine barrier, and pathological changes in podocyte h
Externí odkaz:
https://doaj.org/article/6486c593796f4fa4bf8ff685f8544f3b
Autor:
Jonas Engesser, Robin Khatri, Darius P. Schaub, Yu Zhao, Hans-Joachim Paust, Zeba Sultana, Nariaki Asada, Jan-Hendrik Riedel, Varshi Sivayoganathan, Anett Peters, Anna Kaffke, Saskia-Larissa Jauch-Speer, Thiago Goldbeck-Strieder, Victor G. Puelles, Ulrich O. Wenzel, Oliver M. Steinmetz, Elion Hoxha, Jan-Eric Turner, Hans-Willi Mittrücker, Thorsten Wiech, Tobias B. Huber, Stefan Bonn, Christian F. Krebs, Ulf Panzer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis is a life-threatening autoimmune disease that often results in kidney failure caused by crescentic glomerulonephritis (GN). To date, treatment of most patients with ANCA-GN r
Externí odkaz:
https://doaj.org/article/287d8b69dd7e4d95bc28f18d29e2859c
Autor:
Insa M. Schmidt, Aditya L. Surapaneni, Runqi Zhao, Dhairya Upadhyay, Wan-Jin Yeo, Pascal Schlosser, Courtney Huynh, Anand Srivastava, Ragnar Palsson, Taesoo Kim, Isaac E. Stillman, Daria Barwinska, Jonathan Barasch, Michael T. Eadon, Tarek M. El-Achkar, Joel Henderson, Dennis G. Moledina, Sylvia E. Rosas, Sophie E. Claudel, Ashish Verma, Yumeng Wen, Maja Lindenmayer, Tobias B. Huber, Samir V. Parikh, John P. Shapiro, Brad H. Rovin, Ian B. Stanaway, Neha A. Sathe, Pavan K. Bhatraju, Josef Coresh, the Kidney Precision Medicine Project, Eugene P. Rhee, Morgan E. Grams, Sushrut S. Waikar
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The kidney tubules constitute two-thirds of the cells of the kidney and account for the majority of the organ’s metabolic energy expenditure. Acute tubular injury (ATI) is observed across various types of kidney diseases and may significan
Externí odkaz:
https://doaj.org/article/41855c04b12d4c92a5497040b3021033
Autor:
João Baltar, Rafael Mendes Miranda, Maria Cabral, Sandra Rebelo, Florian Grahammer, Tobias B. Huber, Carlos Reguenga, Filipe Almeida Monteiro
Publikováno v:
Neural Development, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract The cell-adhesion molecule NEPH1 is required for maintaining the structural integrity and function of the glomerulus in the kidneys. In the nervous system of Drosophila and C. elegans, it is involved in synaptogenesis and axon branching, whi
Externí odkaz:
https://doaj.org/article/523764824a2840bab401d48b78bf9204
Autor:
Kevin Roedl, Silvia De Rosa, Marlene Fischer, Josephine Braunsteiner, Christian Schmidt-Lauber, Dominik Jarczak, Tobias B. Huber, Stefan Kluge, Dominic Wichmann
Publikováno v:
Annals of Intensive Care, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Background Critically ill patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requiring veno-venous extracorporeal membrane oxygenation (vv-ECMO) are at risk for acute kidney injury (AKI). Currently, the incidence of A
Externí odkaz:
https://doaj.org/article/11d59d504a2f4f919f8795aecbe3c83b
Autor:
Ann-Christin Gnirck, Marie-Sophie Philipp, Alex Waterhölter, Malte Wunderlich, Nikhat Shaikh, Virginia Adamiak, Lena Henneken, Tobias Kautz, Tingting Xiong, Daniela Klaus, Pascal Tomczyk, Mohamad M. Al-Bahra, Dirk Menche, Mark Walkenhorst, Olivier Lantz, Anne Willing, Manuel A. Friese, Tobias B. Huber, Christian F. Krebs, Ulf Panzer, Christian Kurts, Jan-Eric Turner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Mucosal-associated invariant T (MAIT) cells have been implicated in various inflammatory diseases of barrier organs, but so far, their role in kidney disease is unclear. Here we report that MAIT cells that recognize their prototypical ligand
Externí odkaz:
https://doaj.org/article/ea197fd8a59e40e69a85f91fdcdab807
Autor:
Moritz Lassé, Jamal El Saghir, Celine C. Berthier, Sean Eddy, Matthew Fischer, Sandra D. Laufer, Dominik Kylies, Arvid Hutzfeldt, Léna Lydie Bonin, Bernhard Dumoulin, Rajasree Menon, Virginia Vega-Warner, Felix Eichinger, Fadhl Alakwaa, Damian Fermin, Anja M. Billing, Akihiro Minakawa, Phillip J. McCown, Michael P. Rose, Bradley Godfrey, Elisabeth Meister, Thorsten Wiech, Mercedes Noriega, Maria Chrysopoulou, Paul Brandts, Wenjun Ju, Linda Reinhard, Elion Hoxha, Florian Grahammer, Maja T. Lindenmeyer, Tobias B. Huber, Hartmut Schlüter, Steffen Thiel, Laura H. Mariani, Victor G. Puelles, Fabian Braun, Matthias Kretzler, Fatih Demir, Jennifer L. Harder, Markus M. Rinschen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Kidney organoids are a promising model to study kidney disease, but their use is constrained by limited knowledge of their functional protein expression profile. Here, we define the organoid proteome and transcriptome trajectories over cultu
Externí odkaz:
https://doaj.org/article/39ed8a12de7946c9bcf28c0777cf6607
Publikováno v:
Glomerular Diseases, Vol 3, Iss 1, Pp 230-232 (2023)
Externí odkaz:
https://doaj.org/article/4f90685411294f11a5a08df0e58b98ed
Autor:
Harald Rupprecht, Lorenzo Catanese, Kerstin Amann, Felicitas E. Hengel, Tobias B. Huber, Agnieszka Latosinska, Maja T. Lindenmeyer, Harald Mischak, Justyna Siwy, Ralph Wendt, Joachim Beige
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3678 (2024)
Effective management of chronic kidney disease (CKD), a major health problem worldwide, requires accurate and timely diagnosis, prognosis of progression, assessment of therapeutic efficacy, and, ideally, prediction of drug response. Multiple biomarke
Externí odkaz:
https://doaj.org/article/736e40b136044da9a375bd453d5283c0
Autor:
Lorenzo Catanese, Harald Rupprecht, Tobias B. Huber, Maja T. Lindenmeyer, Felicitas E. Hengel, Kerstin Amann, Ralph Wendt, Justyna Siwy, Harald Mischak, Joachim Beige
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3519 (2024)
Effective management of glomerular kidney disease, one of the main categories of chronic kidney disease (CKD), requires accurate diagnosis, prognosis of progression, assessment of therapeutic efficacy, and, ideally, prediction of drug response. Multi
Externí odkaz:
https://doaj.org/article/7c5732441e8143bebfa4a04a32aad090