Výsledky vyhledávání - "Tobias Atkin"

Akademický článek

Dysfunction in endocannabinoids, palmitoylethanolamide, and degradation of tryptophan into kynurenine in individuals with depressive symptoms

Autor: Stefano Comai, Nicolas Nunez, Tobias Atkin, Maykel F. Ghabrash, Rita Zakarian, Allan Fielding, Marie Saint-Laurent, Nancy Low, Garrett Sauber, Eugenio Ragazzi, Cecilia J. Hillard, Gabriella Gobbi

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)

Abstract Background The endocannabinoid (eCB) system and the serotonin (5-HT) are both implicated in the severity of the depression. 5-HT is synthesized from the amino acid tryptophan (Trp), which is also a precursor for kynurenine (Kyn) whose produc

Externí odkaz: https://doaj.org/article/7fb56a12fc644014872f5422e0b15c65

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Lifelong reductions of PKMζ in ventral hippocampus of nonhuman primates exposed to early-life adversity due to unpredictable maternal care

Autor: Tobias Atkin, Panayiotis Tsokas, Todd Charlton Sacktor, Eric M. Schoenfeld, Changchi Hsieh, Jeremy D. Coplan, Ryan Norris, Sasha Fulton, André A. Fenton

Publikováno v: Learningmemory (Cold Spring Harbor, N.Y.). 28(9)

Protein kinase Mζ (PKMζ) maintains long-term potentiation (LTP) and long-term memory through persistent increases in kinase expression. Early-life adversity is a precursor to adult mood and anxiety disorders, in part, through persistent disruption

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a3e4e9a3741cfc97b8a2309ce456fa
https://pubmed.ncbi.nlm.nih.gov/34400535

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Practitioner Review: The effects of atypical antipsychotics and mood stabilisers in the treatment of depressive symptoms in paediatric bipolar disorder

Autor: Tobias Atkin, Gabriella Gobbi, Nicolas A. Nuñez

Publikováno v: Journal of Child Psychology and Psychiatry. 58:865-879

Background The management of depressive and mixed symptoms in children and adolescents with bipolar disorder (BD) remains a matter of debate. The goal of this review is, thus, to systematically examine the impact of atypical antipsychotics (AAPs) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c611803e353b5c55f37618a1ba817e88
https://doi.org/10.1111/jcpp.12735

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Association of cannabis use in adolescence and risk of depression, anxiety, and suicidality in young adulthood: A systematic review and meta-analysis

Autor: Naomi R. Marmorstein, Tobias Atkin, Gabriella Gobbi, Andrea Cipriani, Sorayya Askari, Shouao Wang, Jill Boruff, Nancy E. Mayo, Tomasz Zytynski, Mark A. Ware, Nandini Dendukuri

Importance Cannabis is the most commonly used drug of abuse by adolescents in the world. While the impact of adolescent cannabis use on the development of psychosis has been investigated in depth, little is known about the impact of cannabis use on m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a336330ce9fb739727faed87fae07a
https://doi.org/10.1001/jamapsychiatry.2018.4500

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Drugs for insomnia beyond benzodiazepines: Pharmacology, clinical applications, and discovery

Autor: Gabriella Gobbi, Stefano Comai, Tobias Atkin

Although the GABAergic benzodiazepines (BZDs) and Z-drugs (zolpidem, zopiclone, and zaleplon) are FDA-approved for insomnia disorders with a strong evidence base, they have many side effects, including cognitive impairment, tolerance, rebound insomni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f94252482db792b20b3cf9663f4335
http://hdl.handle.net/11577/3388163

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