Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Tobias Bittner"'
Autor:
Sterling C. Johnson, Marc Suárez-Calvet, Ivonne Suridjan, Carolina Minguillón, Juan Domingo Gispert, Erin Jonaitis, Agata Michna, Margherita Carboni, Tobias Bittner, Christina Rabe, Gwendlyn Kollmorgen, Henrik Zetterberg, Kaj Blennow
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Alzheimer’s disease (AD) is a complex and heterogeneous disease, which requires reliable biomarkers for diagnosis and monitoring disease activity. Preanalytical protocol and technical variability associated with biomarker immuno
Externí odkaz:
https://doaj.org/article/17f54cedcdf94df687ff54f0a3c72056
Autor:
Kenta Yoshida, Anita Moein, Tobias Bittner, Susanne Ostrowitzki, Helen Lin, Lee Honigberg, Jin Y. Jin, Angelica Quartino
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2020)
Abstract Background Crenezumab, a fully humanized anti-beta-amyloid (Aβ) immunoglobulin G4 (IgG4) monoclonal antibody, binds to both monomeric and aggregated forms of Aβ. We assessed the pharmacokinetics (PK)/pharmacodynamics (PD) of crenezumab and
Externí odkaz:
https://doaj.org/article/2c76e3b461714d7fb634c9deff89de51
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 291-300 (2019)
Abstract Introduction We examined the influence of common preanalytical factors on the measurement of Alzheimer's disease–specific biomarkers in human plasma. Methods Amyloid β peptides (Aβ[1‐40], Aβ[1‐42]) and total Tau plasma concentration
Externí odkaz:
https://doaj.org/article/a87aa502bd3f4841ac68d4e80e7ad450
Autor:
Josef Pannee, Leslie M. Shaw, Magdalena Korecka, Teresa Waligorska, Charlotte E. Teunissen, Erik Stoops, Hugo M. J. Vanderstichele, Kimberley Mauroo, Inge M. W. Verberk, Ashvini Keshavan, Pedro Pesini, Leticia Sarasa, Maria Pascual‐Lucas, Noelia Fandos, José‐Antonio Allué, Erik Portelius, Ulf Andreasson, Ritsuko Yoda, Akinori Nakamura, Naoki Kaneko, Shieh‐Yueh Yang, Huei‐Chun Liu, Stefan Palme, Tobias Bittner, Kwasi G. Mawuenyega, Vitaliy Ovod, James Bollinger, Randall J. Bateman, Yan Li, Jeffrey L. Dage, Erik Stomrud, Oskar Hansson, Jonathan M. Schott, Kaj Blennow, Henrik Zetterberg
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Blood‐based assays to measure brain amyloid beta (Aβ) deposition are an attractive alternative to the cerebrospinal fluid (CSF)–based assays currently used in clinical settings. In this study, we examined different blood‐
Externí odkaz:
https://doaj.org/article/07cf8801f7b140a6a12154efbdfca507
Autor:
Carolin Kurz, Laura Stöckl, Isabelle Schrurs, Ivonne Suridjan, Selim Üstün Gürsel, Tobias Bittner, Alexander Jethwa, Robert Perneczky
Publikováno v:
Journal of neurochemistry 165(1), 95-105 (2023). doi:10.1111/jnc.15757
An unmet need exists for reliable plasma biomarkers of amyloid pathology, in the clinical laboratory setting, to streamline diagnosis of Alzheimer's disease (AD). For routine clinical use, a biomarker must provide robust and reliable results under pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1d539a78773ff98e98935b7b108646
https://doi.org/10.1111/jnc.15757
https://doi.org/10.1111/jnc.15757
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Concerns have been raised about the limited health system capacity for identification of patients who are eligible for a disease‐modifying Alzheimer's treatment (DMT). Blood‐based biomarker (BBBM) tests are a promising tool
Externí odkaz:
https://doaj.org/article/dc075dfa27cb4adeb28a23088e4dc767
Autor:
Stephen Salloway, Lee A. Honigberg, William Cho, Michael Ward, Michel Friesenhahn, Flavia Brunstein, Angelica Quartino, David Clayton, Deborah Mortensen, Tobias Bittner, Carole Ho, Christina Rabe, Stephen P. Schauer, Kristin R. Wildsmith, Reina N. Fuji, Shehnaaz Suliman, Eric M. Reiman, Kewei Chen, Robert Paul
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2018)
Abstract Background We investigated the effect of crenezumab, a humanized anti-amyloid-beta (Aβ) immunoglobulin (Ig)G4 monoclonal antibody, on biomarkers of amyloid pathology, neurodegeneration, and disease progression in patients with mild-to-moder
Externí odkaz:
https://doaj.org/article/a311ee7ca9264e6696bffa8520f93ab9
Autor:
Nicholas C. Cullen, Shorena Janelidze, Niklas Mattsson‐Carlgren, Sebastian Palmqvist, Tobias Bittner, Ivonne Suridjan, Alexander Jethwa, Gwendlyn Kollmorgen, Wagner S. Brum, Henrik Zetterberg, Kaj Blennow, Erik Stomrud, Oskar Hansson
Publikováno v:
Alzheimer's & Dementia. 19:797-806
The effect of random error on the performance of blood-based biomarkers for Alzheimer's disease (AD) must be determined before clinical implementation.We measured test-retest variability of plasma amyloid beta (Aβ)42/Aβ40, neurofilament light (NfL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b122a2004502f5a63ab6e114b7e69a
https://doi.org/10.1002/alz.12706
https://doi.org/10.1002/alz.12706
Autor:
Janice Smith, Michael C. Donohue, Elisabeth Gruendl, Timo Grimmer, Richard J. Perry, Sandra E. Black, Stephen Salloway, Marco Lyons, Loes Rutten-Jacobs, Tobias Bittner, Kaj Blennow, Chris Pelentrides, Frederik Barkhof, Matteo Tonietto, Monika Baudler-Klein, Paulo Fontoura, Rachelle S. Doody
Publikováno v:
Tuesday, April 25.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfb06e24316e32708c4920fdf1440be1
https://doi.org/10.1212/wnl.0000000000203868
https://doi.org/10.1212/wnl.0000000000203868
Autor:
Christina Rabe, Tobias Bittner, Michaela Mertes, Kellie Riley, Alexander Jethwa, Isabelle Schrurs, Galina Babitzki, Erik Stomrud, Sebastian Palmqvist, Reisa A. Sperling, Paul Aisen, Robert A. Rissman, Colin L Masters, Paulo Fontoura, Susanne Ostrowitzki, Oskar Hansson, Rachelle S. Doody
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::983e26fc66eeae8586fe99b5548f91ef
https://doi.org/10.1002/alz.062144
https://doi.org/10.1002/alz.062144