Safety of Probiotic Escherichia coli Strain Nissle 1917 Depends on Intestinal Microbiota and Adaptive Immunity of the Host

Autor: Kerstin Gronbach, Gerd Döring, Frank Leithäuser, Ute Eberle, Jan Hendrik Niess, Ulrich Dobrindt, Martina Müller, Jörg Reimann, Julia-Stefanie Frick, Ingo B. Autenrieth, Tobias Ölschläger

Publikováno v: Infection and Immunity. 78:3036-3046

Probiotics are viable microorganisms that are increasingly used for treatment of a variety of diseases. Occasionally, however, probiotics may have adverse clinical effects, including septicemia. Here we examined the role of the intestinal microbiota

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b6b047243528cb56c8023d23beb089
https://doi.org/10.1128/iai.00218-10

Highly selective antiplasmodial naphthylisoquinoline alkaloids from Ancistrocladus tectorius

Autor: Manik Chatterjee, Gerhard Bringmann, Tobias Ölschläger, August Stich, Jun Wu, Reto Brun, Guoliang Zhang

Publikováno v: Phytochemistry. 91

Naphthylisoquinoline alkaloids, named ancistectorine A1, N-methylancistectorine A1, ancistectorine A2, 5-epi-ancistectorine A2, ancistectorine A3, ancistectorine B1, and ancistectorine C1, have been isolated from twigs of the Chinese plant Ancistrocl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8652c45ee2708a5537b2ef1736110c
https://pubmed.ncbi.nlm.nih.gov/22459968

A colicin M derivative containing the lipoprotein signal sequence is secreted and renders the colicin M target accessible from inside the cells

Autor: Tobias Ölschläger

Publikováno v: Archives of Microbiology. 156:449-454

Colicin M is only released in very low amounts by cells harbouring this plasmid encoded colicin, due to the lack of a release (lysis) protein. A fusion gene (lpp'cma) was constructed which determined two proteins: Lpp'-Cma composed of the signal sequ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397e0d039292a79123aee160eae7d50d
https://doi.org/10.1007/bf00245391

How to become a uropathogen: comparative genomic analysis of extraintestinal pathogenic Escherichia coli strains

Autor: Ulrich Dobrindt, Kaj Albermann, Levente Emödy, Heiko Liesegang, Elzbieta Brzuszkiewicz, Gábor Nagy, Melanie Emmerth, Gerhard Gottschalk, Jörg Hacker, Holger Brüggemann, Carmen Buchrieser, Christian Wagner, Tobias Ölschläger

Publikováno v: Brzuszkiewicz, E, Brüggemann, H, Liesegang, H, Emmerth, M, Olschläger, T, Nagy, G, Albermann, K, Wagner, C H, Buchrieser, C, Emody, L, Gottschalk, G, Hacker, J & Dobrindt, U 2006, ' How to become a uropathogen: comparative genomic analysis of extraintestinal pathogenic Escherichia coli strains ' Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 34, pp. 12879-84 . https://doi.org/10.1073/pnas.0603038103

Uropathogenic Escherichia coli (UPEC) strain 536 (O6:K15:H31) is one of the model organisms of extraintestinal pathogenic E. coli (ExPEC). To analyze this strain's genetic basis of urovirulence, we sequenced the entire genome and compared the data wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2256119918db7b3776c2f57b08e96a57
https://pure.au.dk/portal/da/publications/how-to-become-a-uropathogen-comparative-genomic-analysis-of-extraintestinal-pathogenic-escherichia-coli-strains(e163961a-c0ac-4e98-9aa0-61cec4fd49f1).html

Characterization of Escherichia coli strains isolated from environmental water habitats and from stool samples of healthy volunteers

Autor: Gabriele Blum, U. Wallner, H Heier, Arthur Donohue-Rolfe, Joerg Hacker, Inge Mühldorfer, Helmut Tschäpe, Tobias Ölschläger

Publikováno v: Research in microbiology. 147(8)

This study was undertaken to determine the frequency of pathogenic Escherichia coli strains among wild-type E. coli strain isolates from the microbial flora of healthy volunteers and from natural residential water habitats of a defined geographic are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c52d911126092228b23c86bcd7974e
https://pubmed.ncbi.nlm.nih.gov/9157489