Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Tobias, Winkler"'
Autor:
Tobias Winkler, Sven Geissler, Tazio Maleitzke, Carsten Perka, Georg N. Duda, Alexander Hildebrandt
Publikováno v:
EFORT Open Reviews, Vol 9, Iss 9, Pp 837-844 (2024)
Advanced therapies are expected to play a crucial role in supporting repair after injury, halting the degeneration of musculoskeletal tissue to enable and promote physical activity. Despite advancements, the progress in developing advanced therapies
Externí odkaz:
https://doaj.org/article/0534d29156c54a98bc14e8931ec34547
Autor:
Mara Meyer Günderoth, Alexandra Bannach-Brown, Tobias Winkler, Johannes Keller, Robert Karl Zahn, Tazio Maleitzke
Publikováno v:
EFORT Open Reviews, Vol 9, Iss 7, Pp 600-614 (2024)
Purpose: The aim of this study was to investigate the efficacy of calcitonin (CT) in animal models of experimental osteoarthritis (OA) and rheumatoid arthritis (RA), as new stabilized CT formulations are currently being introduced. Methods: A compreh
Externí odkaz:
https://doaj.org/article/8735c32c8e4a4cf1ba90c18b082f12b8
Publikováno v:
Mechanobiology in Medicine, Vol 2, Iss 4, Pp 100102- (2024)
Recent developments in cell therapy have revolutionized medical treatment. While various methods of stimulation have been explored, the role of mechanical force has often been overlooked. Although mechanical loading is not easily visible, it can acti
Externí odkaz:
https://doaj.org/article/31a3f609debb424584d06dec44d4da91
Autor:
Tu-Lan Vu-Han, Rodrigo Bermudez Schettino, Claudia Weiß, Carsten Perka, Tobias Winkler, Vikram Sunkara, Matthias Pumberger
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract 5q-spinal muscular atrophy (SMA) is a neuromuscular disorder (NMD) that has become one of the first 5% treatable rare diseases. The efficacy of new SMA therapies is creating a dynamic SMA patient landscape, where disease progression and scol
Externí odkaz:
https://doaj.org/article/1e37d33ac7a041a28dfc0c1f80a91e45
Autor:
Felix Eckstein, Thula Cannon Walter-Rittel, Akshay S. Chaudhari, Nicholas M. Brisson, Tazio Maleitzke, Georg N. Duda, Anna Wisser, Wolfgang Wirth, Tobias Winkler
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 3, Pp 100505- (2024)
Objective: This expert opinion paper proposes a design for a state-of-the-art magnetic resonance image (MRI) acquisition protocol for knee osteoarthritis clinical trials in early and advanced disease. Semi-quantitative and quantitative imaging endpoi
Externí odkaz:
https://doaj.org/article/c269e616f30f46968c643456f5bca826
Autor:
Alexander Hildebrandt, Tamara Dietrich, Jérôme Weber, Mara Meyer Günderoth, Sijia Zhou, Florian N. Fleckenstein, Shan Jiang, Tobias Winkler, Georg N. Duda, Serafeim Tsitsilonis, Johannes Keller, Tazio Maleitzke
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-11 (2023)
Abstract Background The vasoactive neuropeptide calcitonin gene-related peptide alpha (αCGRP) enhances nociception in primary knee osteoarthritis (OA) and has been shown to disrupt cartilage and joint integrity in experimental rheumatoid arthritis (
Externí odkaz:
https://doaj.org/article/7fd8d19ce2db4dcf8b7b8bf3d7656959
Publikováno v:
Logical Methods in Computer Science, Vol Volume 19, Issue 4 (2023)
Probabilistic pushdown automata (pPDA) are a standard operational model for programming languages involving discrete random choices and recursive procedures. Temporal properties are useful for specifying the chronological order of events during progr
Externí odkaz:
https://doaj.org/article/66a38ab904844f9cb48f41ed67334b21
Autor:
Marcel Niemann, Melanie Ort, Luis Lauterbach, Mathias Streitz, Andreas Wilhelm, Gerald Grütz, Florian N. Fleckenstein, Frank Graef, Antje Blankenstein, Simon Reinke, Ulrich Stöckle, Carsten Perka, Georg N. Duda, Sven Geißler, Tobias Winkler, Tazio Maleitzke
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Objective Platelet-rich plasma (PRP) therapy is increasingly popular to treat musculoskeletal diseases, including tendinopathies and osteoarthritis (OA). To date, it remains unclear to which extent PRP compositions are determined by the immu
Externí odkaz:
https://doaj.org/article/68783f4df52245348d097f107759d32b
Autor:
Johannes Wischmann, Kathrin Borowski, Joachim Havla, Franziska S. Thaler, Tobias Winkler, Tobias Jung, Andreas Straube, Ilias Masouris
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectivesAnti-septin-5 encephalitis is a rare disease with only few published cases, mainly based on retrospective CSF and serum analyses. Predominant symptoms are cerebellar ataxia and oculomotor abnormalities. Due to the rareness of the disease, t
Externí odkaz:
https://doaj.org/article/476f041b7a044d48ab00bcccd5e8c397
Autor:
Tobias Winkler, Matthew L. Costa, Racheli Ofir, Ornella Parolini, Sven Geissler, Hans-Dieter Volk, Christian Eder
Publikováno v:
Bone & Joint Open, Vol 3, Iss 4, Pp 340-347 (2022)
Aims The aim of the HIPGEN consortium is to develop the first cell therapy product for hip fracture patients using PLacental-eXpanded (PLX-PAD) stromal cells. Methods HIPGEN is a multicentre, multinational, randomized, double-blind, placebo-controlle
Externí odkaz:
https://doaj.org/article/04d98ec8fb3a4b2cb838b809c838455d