Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Tobias, Sahr"'
Autor:
Rahul Sharma, Michael Adams, Simonne Griffith-Jones, Tobias Sahr, Laura Gomez-Valero, Felix Weis, Michael Hons, Sarah Gharbi, Rayene Berkane, Alexandra Stolz, Carmen Buchrieser, Sagar Bhogaraju
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Legionella pneumophila (LP) secretes more than 300 effectors into the host cytosol to facilitate intracellular replication. One of these effectors, SidH, 253 kDa in size with no sequence similarity to proteins of known function is toxic when
Externí odkaz:
https://doaj.org/article/2d88ff0f17214a348ccac44f567c6f37
Autor:
Tobias Sahr, Pedro Escoll, Christophe Rusniok, Sheryl Bui, Gérard Pehau-Arnaudet, Gregory Lavieu, Carmen Buchrieser
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Legionella pneumophila expresses a range of bacterial determinants that mimic eukaryotic functions. Here the authors show small RNAs of L.pneumophila mimic eukaryotic microRNA and modulate the host response to infection.
Externí odkaz:
https://doaj.org/article/3df97bae629b4c4cb76dc65b011ff7e6
Autor:
Pedro Escoll, Lucien Platon, Mariatou Dramé, Tobias Sahr, Silke Schmidt, Christophe Rusniok, Carmen Buchrieser
Publikováno v:
eLife, Vol 10 (2021)
Legionella pneumophila, the causative agent of Legionnaires’ disease, a severe pneumonia, injects via a type 4 secretion system (T4SS) more than 300 proteins into macrophages, its main host cell in humans. Certain of these proteins are implicated i
Externí odkaz:
https://doaj.org/article/61a858dc6ffb4cb69321f87988334e37
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Legionella pneumophila is a gram-negative bacterium that inhabits freshwater ecosystems, where it is present in biofilm or as planktonic form. L. pneumophila is mainly found associated with protozoa, which serve as protection from hostile environment
Externí odkaz:
https://doaj.org/article/25d203a455274d43b6d6164c48cbcfe9
Autor:
Cyril Matthey-Doret, Morgan J. Colp, Pedro Escoll, Agnès Thierry, Pierrick Moreau, Bruce Curtis, Tobias Sahr, Matt Sarrasin, Michael W. Gray, B. Franz Lang, John M. Archibald, Carmen Buchrieser, Romain Koszul
Publikováno v:
Genome Research
Genome Research, 2022, 32 (9), pp.1698-1710. ⟨10.1101/gr.276375.121⟩
Genome Research, 2022, 32 (9), pp.1698-1710. ⟨10.1101/gr.276375.121⟩
The unicellular amoeba Acanthamoeba castellanii is ubiquitous in aquatic environments, where it preys on bacteria. The organism also hosts bacterial endosymbionts, some of which are parasitic, including human pathogens such as Chlamydia and Legionell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd84e1335c51304c2246e05359eb63b
https://hal-pasteur.archives-ouvertes.fr/pasteur-03913195/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03913195/document
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Legionella pneumophila is an environmental bacterium that parasitizes protozoa, but it may also infect humans, thereby causing a severe pneumonia called Legionnaires’ disease. To cycle between the environment and a eukaryotic host, L. pneu
Externí odkaz:
https://doaj.org/article/c7950b9fecdd4facb8c8391ea8332abb
Autor:
Tobias Sahr, Christophe Rusniok, Francis Impens, Giulia Oliva, Odile Sismeiro, Jean-Yves Coppée, Carmen Buchrieser
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006629 (2017)
The carbon storage regulator protein CsrA regulates cellular processes post-transcriptionally by binding to target-RNAs altering translation efficiency and/or their stability. Here we identified and analyzed the direct targets of CsrA in the human pa
Externí odkaz:
https://doaj.org/article/e7a25920a5414841a456fb07aba08215
Autor:
Ina Häuslein, Tobias Sahr, Pedro Escoll, Nadine Klausner, Wolfgang Eisenreich, Carmen Buchrieser
Publikováno v:
Open Biology, Vol 7, Iss 11 (2017)
Legionella pneumophila CsrA plays a crucial role in the life-stage-specific expression of virulence phenotypes and metabolic activity. However, its exact role is only partly known. To elucidate how CsrA impacts L. pneumophila metabolism we analysed t
Externí odkaz:
https://doaj.org/article/6cf6aeb409d84909b9cad4bc67c8a089
Autor:
Cyril, Matthey-Doret, Morgan J, Colp, Pedro, Escoll, Agnès, Thierry, Pierrick, Moreau, Bruce, Curtis, Tobias, Sahr, Matt, Sarrasin, Michael W, Gray, B Franz, Lang, John M, Archibald, Carmen, Buchrieser, Romain, Koszul
Publikováno v:
Genome research.
The unicellular amoeba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53d81ecdc4fcd3e579026c4da1a8ea35
https://pubmed.ncbi.nlm.nih.gov/36109147
https://pubmed.ncbi.nlm.nih.gov/36109147