Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Tobias, Ruck"'
Autor:
Alexander Schaiter, Andreas Hentschel, Felix Kleefeld, Julia Schuld, Vincent Umathum, Tara Procida-Kowalski, Christopher Nelke, Angela Roth, Andreas Hahn, Heidrun H. Krämer, Tobias Ruck, Rita Horvath, Peter F. M. van der Ven, Marek Bartkuhn, Andreas Roos, Anne Schänzer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract To gain a deeper understanding of skeletal muscle function in younger age and aging in elderly, identification of molecular signatures regulating these functions under physiological conditions is needed. Although molecular studies of healthy
Externí odkaz:
https://doaj.org/article/194ae0f583e44868afbde68598f4c31c
Autor:
I-Na Lu, Phyllis Fung-Yi Cheung, Michael Heming, Christian Thomas, Giovanni Giglio, Markus Leo, Merve Erdemir, Timo Wirth, Simone König, Christine A. Dambietz, Christina B. Schroeter, Christopher Nelke, Jens T. Siveke, Tobias Ruck, Luisa Klotz, Carmen Haider, Romana Höftberger, Christoph Kleinschnitz, Heinz Wiendl, Tim Hagenacker, Gerd Meyer zu Horste
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract 5q-associated spinal muscular atrophy (SMA) is a motoneuron disease caused by mutations in the survival motor neuron 1 (SMN1) gene. Adaptive immunity may contribute to SMA as described in other motoneuron diseases, yet mechanisms remain elus
Externí odkaz:
https://doaj.org/article/fb6284ab7fac4a1d86c729a732971fab
Autor:
Lars Masanneck, Jan Voth, Niklas Huntemann, Menekse Öztürk, Christina B. Schroeter, Tobias Ruck, Sven G. Meuth, Marc Pawlitzki
Publikováno v:
Neurological Research and Practice, Vol 5, Iss 1, Pp 1-7 (2023)
Abstract Introduction Chronic inflammatory demyelinating polyneuropathy (CIDP) is one of the most common immune neuropathies leading to severe impairments in daily life. Current treatment options include intravenous immunoglobulins (IVIG), which are
Externí odkaz:
https://doaj.org/article/e2a8ca5a1952457eb18e62335e1064e3
Autor:
Julian Alexander Schreiber, Anastasia Derksen, Gunnar Goerges, Sven Schütte, Jasmin Sörgel, Aytug K. Kiper, Nathalie Strutz-Seebohm, Tobias Ruck, Sven G. Meuth, Niels Decher, Guiscard Seebohm
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract The TWIK-related spinal cord K + channel (TRESK, K2P18.1) is a K2P channel contributing to the maintenance of membrane potentials in various cells. Recently, physiological TRESK function was identified as a key player in T-cell differentiati
Externí odkaz:
https://doaj.org/article/cd1204a78c1b47188a3f54d455330200
Autor:
Hruy Menghesha, Michael Schroeter, Christopher Nelke, Tobias Ruck, Georg Schlachtenberger, Clara Welskop, Amina Camo, Matthias Heldwein, Gerardus Bennink, Thorsten Wahlers, Servet Bölükbas, Fabian Doerr, Khosro Hekmat
Publikováno v:
Neurological Research and Practice, Vol 5, Iss 1, Pp 1-10 (2023)
Abstract Background Myasthenia gravis (MG) is a rare neuromuscular disorder. Symptoms can range from ptosis only to life threatening myasthenic crisis. Thymectomy is recommended for anti-acetylcholine receptor-antibody positive patients with early-on
Externí odkaz:
https://doaj.org/article/e6ea4e184ca3454a8640ced0950ef832
Autor:
Lukas Theissen, Christina B. Schroeter, Niklas Huntemann, Saskia Räuber, Vera Dobelmann, Derya Cengiz, Alexander Herrmann, Kathrin Koch-Hölsken, Norbert Gerdes, Hao Hu, Philipp Mourikis, Amin Polzin, Malte Kelm, Hans-Peter Hartung, Sven G. Meuth, Christopher Nelke, Tobias Ruck
Publikováno v:
Cells, Vol 13, Iss 6, p 508 (2024)
Myasthenia gravis (MG) is a prototypical autoimmune disease of the neuromuscular junction (NMJ). The study of the underlying pathophysiology has provided novel insights into the interplay of autoantibodies and complement-mediated tissue damage. Exper
Externí odkaz:
https://doaj.org/article/f4973adcbfe1453db7ec94a458ee2aec
Autor:
Mustafa Sindi, Christina Hecker, Andrea Issberner, Tobias Ruck, Sven G. Meuth, Philipp Albrecht, Michael Dietrich
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn multiple sclerosis (MS), chronic disability primarily stems from axonal and neuronal degeneration, a condition resistant to conventional immunosuppressive or immunomodulatory treatments. Recent research has indicated that selective sph
Externí odkaz:
https://doaj.org/article/953fbe3b51dc4d16831d9fa78a3c884c
Autor:
Saskia Räuber, Christopher Nelke, Christina B. Schroeter, Sumanta Barman, Marc Pawlitzki, Jens Ingwersen, Katja Akgün, Rene Günther, Alejandra P. Garza, Michaela Marggraf, Ildiko Rita Dunay, Stefanie Schreiber, Stefan Vielhaber, Tjalf Ziemssen, Nico Melzer, Tobias Ruck, Sven G. Meuth, Michael Herty
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionGiven its wide availability and cost-effectiveness, multidimensional flow cytometry (mFC) became a core method in the field of immunology allowing for the analysis of a broad range of individual cells providing insights into cell subset c
Externí odkaz:
https://doaj.org/article/78b006fa17b54fda8cd7b21145d6c1ab
Autor:
Marc Pawlitzki, Laura Acar, Lars Masanneck, Alice Willison, Liesa Regner-Nelke, Christopher Nelke, Helmut L’hoest, Ursula Marschall, Jens Schmidt, Sven G. Meuth, Tobias Ruck
Publikováno v:
Neurological Research and Practice, Vol 4, Iss 1, Pp 1-11 (2022)
Abstract Background The medical care of patients with myositis is a great challenge in clinical practice. This is due to the rarity of these disease, the complexity of diagnosis and management as well as the lack of systematic analyses. Objectives Th
Externí odkaz:
https://doaj.org/article/d35dd452430440b08d7dcc282b5fb5e0
Real-world evidence on siponimod treatment in patients with secondary progressive multiple sclerosis
Autor:
Liesa Regner-Nelke, Marc Pawlitzki, Alice Willison, Leoni Rolfes, Sinem-Hilal Oezalp, Christopher Nelke, Tristan Kölsche, Melanie Korsen, Matthias Grothe, Sergiu Groppa, Felix Luessi, Sinah Engel, Gereon Nelles, Eckhard Bonmann, Holger Roick, Anke Friedrich, Philipp Knorn, Harald Landefeld, Zoltan Biro, Michael Ernst, Antonios Bayas, Martina Menacher, Katja Akgün, Christoph Kleinschnitz, Tobias Ruck, Tjalf Ziemssen, Refik Pul, Sven G. Meuth
Publikováno v:
Neurological Research and Practice, Vol 4, Iss 1, Pp 1-11 (2022)
Abstract Background Therapeutic options targeting inflammation in multiple sclerosis (MS) have evolved rapidly for relapsing–remitting MS, whereas few therapies are available for progressive forms of MS, in particular secondary progressive MS (SPMS
Externí odkaz:
https://doaj.org/article/ae53dbd9ba474b64ab5dcb39c73e00f6