Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Tobias, Moll"'
Autor:
Wan-Ping Huang, Brittany C.S. Ellis, Rachel E. Hodgson, Anna Sanchez Avila, Vedanth Kumar, Jessica Rayment, Tobias Moll, Tatyana A. Shelkovnikova
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114421- (2024)
Summary: TDP-43 protein is dysregulated in several neurodegenerative diseases, which often have a multifactorial nature and may have extrinsic stressors as a “second hit.” TDP-43 undergoes reversible nuclear condensation in stressed cells includi
Externí odkaz:
https://doaj.org/article/04538c47df7d47c29b8b037208cea959
Autor:
Calum Harvey, Marcel Weinreich, James A.K. Lee, Allan C. Shaw, Laura Ferraiuolo, Heather Mortiboys, Sai Zhang, Paul J. Hop, Ramona A.J. Zwamborn, Kristel van Eijk, Thomas H. Julian, Tobias Moll, Alfredo Iacoangeli, Ahmad Al Khleifat, John P. Quinn, Abigail L. Pfaff, Sulev Kõks, Joanna Poulton, Stephanie L. Battle, Dan E. Arking, Michael P. Snyder, Jan H. Veldink, Kevin P. Kenna, Pamela J. Shaw, Johnathan Cooper-Knock
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e24975- (2024)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving selective vulnerability of energy-intensive motor neurons (MNs). It has been unclear whether mitochondrial function is an upstream driver or a downstream modifier of n
Externí odkaz:
https://doaj.org/article/3a074f5bc5b844fb908962fcae463ee2
Autor:
Thomas H Julian, Nicholas Glascow, A Dylan Fisher Barry, Tobias Moll, Calum Harvey, Yann C Klimentidis, Michelle Newell, Sai Zhang, Michael P Snyder, Johnathan Cooper-Knock, Pamela J Shaw
Publikováno v:
EBioMedicine, Vol 68, Iss , Pp 103397- (2021)
Background: Amyotrophic lateral sclerosis (ALS) is a universally fatal neurodegenerative disease. ALS is determined by gene-environment interactions and improved understanding of these interactions may lead to effective personalised medicine. The rol
Externí odkaz:
https://doaj.org/article/b14f3c3d161c4cbdb4b00a743b2e8d20
Autor:
Johnathan Cooper-Knock, Sai Zhang, Kevin P. Kenna, Tobias Moll, John P. Franklin, Samantha Allen, Helia Ghahremani Nezhad, Alfredo Iacoangeli, Nancy Y. Yacovzada, Chen Eitan, Eran Hornstein, Eran Ehilak, Petra Celadova, Daniel Bose, Sali Farhan, Simon Fishilevich, Doron Lancet, Karen E. Morrison, Christopher E. Shaw, Ammar Al-Chalabi, Jan H. Veldink, Janine Kirby, Michael P. Snyder, Pamela J. Shaw, Ian Blair, Naomi Wray, Matthew Kiernan, Miguel Mitne Neto, Adriano Chio, Ruben Cauchi, Wim Robberecht, Philip van Damme, Phillippe Corcia, Phillipe Couratier, Orla Hardiman, Russel McLaughlin, Marc Gotkine, Vivan Drory, Nicola Ticozzi, Vincenzo Silani, Jan Veldink, Leonard van den Berg, Mamede de Carvalho, Jesus Mora Pardina, Monica Povedano, Peter Andersen, Markus Wber, Nazli Başak, Christopher Shaw, Pamela Shaw, Karen Morrison, John Landers, Jonathan Glass
Publikováno v:
Cell Reports, Vol 33, Iss 9, Pp 108456- (2020)
Summary: Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease. CAV1 and CAV2 organize membrane lipid rafts (MLRs) important for cell signaling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vi
Externí odkaz:
https://doaj.org/article/7fac5ebf332545088de18b27ea1f88df
Autor:
Tobias Moll
Publikováno v:
Spiritual Care. 11:203-211
The topic spirituality at work is becoming increasingly important in the scientific management research, while various concepts of and approaches to new work are attracting more and more attention regarding for instance the trend toward a knowledge s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ddd05a40ee93dcf5d36ab2880852c99
https://doi.org/10.1515/spircare-2021-0017
https://doi.org/10.1515/spircare-2021-0017
Publikováno v:
Journal of Management, Spirituality & Religion. 19:21-44
Although research has established a positive link between spirituality or religiousness and job satisfaction, this influence's pathways remain a 'black box'. Whether it is an effect of a trait- relationship or of a need-satisfaction- relationship rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f8911d3a26dbb57ba0c9f58aee62c70
https://doi.org/10.51327/tkjm6011
https://doi.org/10.51327/tkjm6011
Autor:
Pamela J. Shaw, Nikita Soni, Tobias Moll, Jack N G Marshall, Sai Zhang, Johnathan Cooper-Knock
Publikováno v:
Essays in Biochemistry
Age-associated neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD) and Alzheimer's disease (AD) are an unmet health need, with significant economic and societal implications, and an ever-increasing prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49361db2d358a3bd30db78085a64e0a
https://doi.org/10.1042/ebc20210026
https://doi.org/10.1042/ebc20210026
Autor:
Michael Snyder, Johnathan Cooper-Knock, Pamela J. Shaw, Sarah L Boddy, Sai Zhang, Calum Harvey, Christopher J McDermott, Mahjabin Islam, Katherine J Whittaker, Julian M. Kurz, Tobias Moll, Thomas Julian
Publikováno v:
Brain
Amyotrophic lateral sclerosis is a relatively common and rapidly progressive neurodegenerative disease that, in the majority of cases, is thought to be determined by a complex gene–environment interaction. Exponential growth in the number of perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818e72f6fe89e8f9bfd0df0c930f6b0e
https://doi.org/10.1093/brain/awab420
https://doi.org/10.1093/brain/awab420
Spirituality as Buffer between Negative Effects of the Corona Pandemic and Life and Job Satisfaction
Publikováno v:
Academy of Management Proceedings. 2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b0400d7583db5be37232f20cf412afe
https://doi.org/10.5465/ambpp.2022.13220abstract
https://doi.org/10.5465/ambpp.2022.13220abstract
Autor:
Tobias Moll, Emily Graves, Agnieszka Urbanek, Nikita Soni, Ramya Ranganathan, Adrian Higginbottom, Shanshan Wang, Brian P Head, Johnathan Cooper-Knock, Pamela J Shaw
Mutations within GLT8D1 contribute to familial amyotrophic lateral sclerosis. Pathogenic mutations impair GLT8D1 glycosyltransferase enzymatic function via a dominant negative mechanism, yet the downstream mechanism leading to neurotoxicity is unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fea1c2f59ecf6a55afc5567944ec8f
https://doi.org/10.1101/2022.06.28.497990
https://doi.org/10.1101/2022.06.28.497990
