Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tobias, Lohmeyer"'
Autor:
Josef S Smolen, Tobias Lohmeyer, Julia S. Brunner, Emine Sahin, Kurt Redlich, Martin Friedrich, Victoria Saferding, Birgit Niederreiter, Antonia Puchner, Gernot Schabbauer, Stephan Blüml, Peter Mandl
Publikováno v:
Annals of the Rheumatic Diseases; Vol 74
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases
ObjectiveLocal bone destruction in rheumatic diseases, which often leads to disability and severely reduced quality of life, is almost exclusively mediated by osteoclasts. Therefore, it is important to understand pathways regulating the generation of
Autor:
Stephan, Blüml, Emine, Sahin, Victoria, Saferding, Eliana, Goncalves-Alves, Eva, Hainzl, Birgit, Niederreiter, Anastasia, Hladik, Tobias, Lohmeyer, Julia S, Brunner, Michael, Bonelli, Marije I, Koenders, Wim B, van den Berg, Giulio, Superti-Furga, Josef S, Smolen, Gernot, Schabbauer, Kurt, Redlich
Publikováno v:
Arthritis Research & Therapy
Introduction Autoreactive T cells are a central element in many systemic autoimmune diseases. The generation of these pathogenic T cells is instructed by antigen-presenting cells (APCs). However, signaling pathways in APCs that drive autoimmune disea
Autor:
Gernot Schabbauer, Birgit Niederreiter, Mario Kuttke, Hannes Datler, Julia B. Kral, Emine Sahin, Alexander M. Dohnal, Thomas Haider, Victoria Saferding, Nick Neuwinger, Eva Hainzl, Leslie Hanzl, Angela Halfmann, Stephan Blüml, Gerhard Krönke, Elisabeth Zinser, Klara Soukup, Tobias Lohmeyer, Hannah Paar, Julia S. Brunner
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 195(6)
The PI3K signaling cascade in APCs has been recognized as an essential pathway to initiate, maintain, and resolve immune responses. In this study, we demonstrate that a cell type–specific loss of the PI3K antagonist phosphatase and tensin homolog (
Autor:
Gernot Schabbauer, Antonia Puchner, Stephan Blüml, Kurt Redlich, Emine Sahin, Josef S Smolen, Birgit Niederreiter, Martin Friedrich, Tobias Lohmeyer, Victoria Saferding
Publikováno v:
Annals of the Rheumatic Diseases. 72:A66.3-A67
Background Local bone destruction in rheumatoid arthritis, psoriasis arthritis or ankylosing spondylitis is a serious health burden and the major cause of disability and severely reduced quality of life in these diseases. This damage to the bony stru
Autor:
Martin Friedrich, Antonia Puchner, George Kollias, Josef S. Smolen, Stephan Blüml, Kurt Redlich, Tobias Lohmeyer, Gernot Schabbauer, Birgit Niederreiter
Publikováno v:
Annals of the Rheumatic Diseases. 71:A67.1-A67
Systemic bone loss in diseases such as osteoporosis or local bone destruction in rheumatoid arthritis, proriasis arthritis or ankylosing spondylitis often leads to disability and severely reduced quality of life. This damage to the bony structures is