Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Tobias, Baumgart"'
Autor:
Samsuzzoha Mondal, Karthik Narayan, Samuel Botterbusch, Imania Powers, Jason Zheng, Honey Priya James, Rui Jin, Tobias Baumgart
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Here the authors show that protein phase separation is a key mechanism in cellular receptor internalization via fast endophilin mediated endocytosis (FEME). Phase separation facilitates multivalent FEME-protein assembly in this clathrin-independent p
Externí odkaz:
https://doaj.org/article/eb88be9e379b4997bb94720b21511499
Publikováno v:
Bio-Protocol, Vol 13, Iss 12 (2023)
Bin/Amphiphysin/Rvs (BAR) proteins are known as classical membrane curvature generators during endocytosis. Amphiphysin, a member of the N-BAR sub-family of proteins that contain a characteristic amphipathic sequence at the N-terminus of the BAR doma
Externí odkaz:
https://doaj.org/article/b31f0dd281244ee2b8e9e79666c890ac
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract BAR (Bin/Amphiphysin/Rvs) domain containing proteins function as lipid bilayer benders and curvature sensors, and they contribute to membrane shaping involved in cell signaling and metabolism. The mechanism for their membrane shape sensing h
Externí odkaz:
https://doaj.org/article/0877ef93f64049be80f3a0f3b9799073
Publikováno v:
ACS Omega, Vol 6, Iss 32, Pp 20790-20803 (2021)
Externí odkaz:
https://doaj.org/article/1bb705742bcd4ad8b8ef849259e14096
Autor:
Mehdi Molaei, Sreeja Kutti Kandy, Zachary T. Graber, Tobias Baumgart, Ravi Radhakrishnan, John C. Crocker
Publikováno v:
Physical Review Research, Vol 4, Iss 1, p L012027 (2022)
Lipid bilayer membranes undergo rapid bending undulations with wavelengths from tens of nanometers to tens of microns due to thermal fluctuations. Here, we probe such undulations and the membranes' mechanics by measuring the time-varying orientation
Externí odkaz:
https://doaj.org/article/874e0f0683984ea9ad927196826f6717
Autor:
Samuel Botterbusch, Tobias Baumgart
Publikováno v:
Applied Sciences, Vol 11, Iss 3, p 1288 (2021)
Liquid-liquid phase separation has recently emerged as an important fundamental organizational phenomenon in biological settings. Most studies of biological phase separation have focused on droplets that “condense” from solution above a critical
Externí odkaz:
https://doaj.org/article/ff455175a4fb4a9cada3f2f55fa52137
Publikováno v:
ACS Omega, Vol 6, Iss 32, Pp 20790-20803 (2021)
ACS Omega
ACS Omega
Endophilin, which is a member of the Bin-amphiphysin-Rvs (BAR) domain protein superfamily, contains a homodimeric N-BAR domain of a characteristic crescent shape. The N-BAR domain comprises a six-helix bundle and is known to sense and generate membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73a1201fc0614a66364734839dc112d
https://doaj.org/article/1bb705742bcd4ad8b8ef849259e14096
https://doaj.org/article/1bb705742bcd4ad8b8ef849259e14096
Integrins Modulate T Cell Receptor Signaling by Constraining Actin Flow at the Immunological Synapse
Autor:
Katarzyna I. Jankowska, Edward K. Williamson, Nathan H. Roy, Daniel Blumenthal, Vidhi Chandra, Tobias Baumgart, Janis K. Burkhardt
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Full T cell activation requires coordination of signals from multiple receptor–ligand pairs that interact in parallel at a specialized cell–cell contact site termed the immunological synapse (IS). Signaling at the IS is intimately associated with
Externí odkaz:
https://doaj.org/article/712751ae11394136ba488f040e6af057
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192667 (2018)
Phosphatidylinositides play important roles in cellular signaling and migration. Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) is an important phosphatidylinositide because it acts as a secondary messenger to trigger cell movement and prolif
Externí odkaz:
https://doaj.org/article/7623f720a22944aea4453d70b0cdcc0e
Autor:
Tobias Baumgart, Rui Jin
Publikováno v:
Soft Matter
Lipid oxidation, detected in metabolic processes, is induced in excess when the cellular membrane suffers extra oxidative stress. Lipid oxidation can compromise biomembrane function in part through perturbations of lipid packing, membrane permeabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b50236016a39131977ddb57dbd0a452
https://doi.org/10.1039/d1sm00652e
https://doi.org/10.1039/d1sm00652e