Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tobechukwu K. Ukah"'
Autor:
Christine M. Hoeman, Tobechukwu K. Ukah, Mindy M. Miller, Alexis N. Cattin-Roy, Subhasis Barik, Habib Zaghouani
Publikováno v:
J Immunol
Early life immune responses are deficient in Th1 lymphocytes that compromise neonatal vaccination. We found that IL-4 and IL-13 engage a developmentally expressed IL-4Rα/IL-13Rα1 heteroreceptor to endow IFN regulatory factor 1 (IRF-1) with apoptoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3284cf92c9ae01505e91feb8f7ee34d
https://doi.org/10.4049/jimmunol.1800943
https://doi.org/10.4049/jimmunol.1800943
Autor:
Tobechukwu K. Ukah, Subhasis Barik, Emma Teixeiro, Habib Zaghouani, Mindy M. Miller, Alexis N. Cattin-Roy
Publikováno v:
J Immunol
Early thymic progenitors (ETPs) are bone marrow–derived hematopoietic stem cells that remain multipotent and give rise to a variety of lineage-specific cells. Recently, we discovered a subset of murine ETPs that expresses the IL-4Rα/IL-13Rα1 hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac799284c46b555a6d18f285a6ec4bc
https://pubmed.ncbi.nlm.nih.gov/32917785
https://pubmed.ncbi.nlm.nih.gov/32917785
Publikováno v:
Cell Immunol
Ig-GAD2, an antigen-specific immune modulator, requires bone marrow (BM) cell transfer in order to restore beta (β)-cell formation and induce recovery from established type 1 diabetes (T1D). The BM cells provide endothelial precursor cells (EPCs) th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1a774bd013c27dcb5f924e89fcc563
https://doi.org/10.1016/j.cellimm.2021.104360
https://doi.org/10.1016/j.cellimm.2021.104360
Autor:
Subhasis Barik, Weirong Chen, Mindy M. Miller, Tobechukwu K. Ukah, Alexis N. Cattin-Roy, Habib Zaghouani
Publikováno v:
The Journal of Immunology. 199:2767-2776
Early thymic progenitors (ETPs) are endowed with diverse potencies and can give rise to myeloid and lymphoid lineage progenitors. How the thymic environment guides ETP commitment and maturation toward a specific lineage remains obscure. We have previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b25b3751b7a250eed224b2f697f066e
https://doi.org/10.4049/jimmunol.1700498
https://doi.org/10.4049/jimmunol.1700498
Autor:
Alexis N. Cattin-Roy, Weirong Chen, Habib Zaghouani, Xiaoxiao Wan, Subhasis Barik, Tobechukwu K. Ukah, Mindy M. Miller
Publikováno v:
The Journal of Immunology. 197:3554-3565
To contain autoimmunity, pathogenic T cells must be eliminated or diverted from reaching the target organ. Recently, we defined a novel form of T cell tolerance whereby treatment with Ag downregulates expression of the chemokine receptor CXCR3 and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc6b24f6737db924f652829c73dc8bd
https://doi.org/10.4049/jimmunol.1601032
https://doi.org/10.4049/jimmunol.1601032
Publikováno v:
Cellular immunology. 331
IL-13 receptor alpha 1 (IL-13Rα1) associates with IL-4Rα to form a functional IL-4Rα/IL-13Rα1 heteroreceptor (HR) through which both IL-4 and IL-13 signal. Recently, HR expression was associated with the development of M2 type macrophages which f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8266a3d4ed7929664468500d2f57df
https://pubmed.ncbi.nlm.nih.gov/29929727
https://pubmed.ncbi.nlm.nih.gov/29929727
Autor:
Cuong Q. Diep, Zhenzhen Peng, Alan J. Davidson, Tobechukwu K. Ukah, Renee V. Daigle, Paul M. Kelly
Publikováno v:
genesis. 53:257-269
The vertebrate kidney plays an essential role in removing metabolic waste and balancing water and salt. This is carried out by nephrons, which comprise a blood filter attached to an epithelial tubule with proximal and distal segments. In zebrafish, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::217105036a55c5f434ab1608bc1cae4f
https://doi.org/10.1002/dvg.22846
https://doi.org/10.1002/dvg.22846
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(10)
Recently we reported that IL-4 and IL-13 signaling in murine early thymic progenitors (ETPs) expressing the heteroreceptor (HR) comprising IL-4 receptor α (IL-4Rα) and IL-13 receptor α 1 (IL-13Rα1) activate STAT6 and inhibit ETP maturation potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6016f361dfb20257ddea35b8d30e6fc
https://pubmed.ncbi.nlm.nih.gov/30291166
https://pubmed.ncbi.nlm.nih.gov/30291166
Autor:
Habib Zaghouani, Alexis N. Cattin-Roy, Subhasis Barik, Jason S. Ellis, Jason A. Cascio, Tobechukwu K. Ukah, Mindy M. Miller
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(7)
IL-4 and IL-13 have been defined as anti-inflammatory cytokines that can counter myelin-reactive T cells and modulate experimental allergic encephalomyelitis. However, it is not known whether endogenous IL-4 and IL-13 contribute to the maintenance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d943e9485d86ff6d50e2b5e55933f78
https://pubmed.ncbi.nlm.nih.gov/28801358
https://pubmed.ncbi.nlm.nih.gov/28801358