Zobrazeno 1 - 10
of 1 139
pro vyhledávání: '"To-ichi Hirata"'
Autor:
Chihiro Ochiai, Sonoko Miyauchi, Yuta Kudo, Yuta Naruke, Syuji Yoneyama, Keisuke Tomita, Leng Dongze, Yusuke Chiba, To-Ichi Hirata, Toshihiro Ichijo, Kazuya Nagai, Sota Kobayashi, Shinji Yamada, Hirokazu Hikono, Kenji Murakami
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256588 (2021)
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis (EBL), a malignant B cell lymphoma. However, the mechanisms of BLV-associated lymphomagenesis remain poorly understood. Here, after deep sequencing, we performed comparati
Externí odkaz:
https://doaj.org/article/a240ec0b8aea426e801200ef46ebc662
Autor:
Takuya Iino, Manabu Nagao, Hidekazu Tanaka, Sachiko Yoshikawa, Junko Asakura, Makoto Nishimori, Masakazu Shinohara, Amane Harada, Shunsuke Watanabe, Tatsuro Ishida, Ken-ichi Hirata, Ryuji Toh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The pathophysiology of variant transthyretin (TTR) amyloidosis (ATTRv) is associated with destabilizing mutations in the TTR tetramer. However, why TTR with a wild-type genetic sequence misfolds and aggregates in wild-type transthyretin amyl
Externí odkaz:
https://doaj.org/article/0649b95f344746439c3c1bbcebaf3940
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 4, Pp 259-263 (2024)
This study aimed to develop a method to evaluate the quality of bovine in vitro fertilized (IVF) embryos based on gene expression profiling via whole-transcriptome amplification. The expression of 11 developmentally important genes in individual bovi
Externí odkaz:
https://doaj.org/article/708cc27355824d72beb2a895284db464
Autor:
Taishi Inoue, Takuo Emoto, Katsuhiro Yamanaka, Shunya Chomei, Shunsuke Miyahara, Hiroaki Takahashi, Ryohei Shinohara, Takeshi Kondo, Masayuki Taniguchi, Tomoyuki Furuyashiki, Tomoya Yamashita, Ken-ichi Hirata, Kenji Okada
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract There is no treatment for acute aortic dissection (AAD) targeting inflammatory cells. We aimed to identify the new therapeutic targets associated with inflammatory cells. We characterized the specific distribution of myeloid cells of both hu
Externí odkaz:
https://doaj.org/article/445c7263f743432e91bcebb0f2b4f1e1
Autor:
Susumu Odajima, Wataru Fujimoto, Misa Takegami, Kunihiro Nishimura, Masamichi Iwasaki, Masanori Okuda, Akihide Konishi, Masakazu Shinohara, Manabu Nagao, Ryuji Toh, Ken‐ichi Hirata, Hidekazu Tanaka
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 19 (2024)
Background Stage B heart failure (HF) refers to structural heart disease without signs or symptoms of HF, so that early intervention may delay or prevent the onset of overt HF. However, stage B HF is a very broad concept, and risk stratification of s
Externí odkaz:
https://doaj.org/article/0039c0bd0d924d0283f51dc018d9384a
Autor:
Masato Ogawa, PT, PhD, Seimi Satomi-Kobayashi, MD, PhD, Mari Hamaguchi, MD, Kodai Komaki, PT, Hifumi Kusu, PT, Kazuhiro P. Izawa, PT, PhD, Shunsuke Miyahara, MD, PhD, Yoshitada Sakai, MD, PhD, Ken-ichi Hirata, MD, PhD, Kenji Okada, MD, PhD
Publikováno v:
JTCVS Open, Vol 18, Iss , Pp 123-137 (2024)
Objective: The incidence of postoperative complications, including dysphagia, increases as the population undergoing cardiovascular surgery ages. This study aimed to explore the potential of maximum phonation time (MPT) as a simple tool for predictin
Externí odkaz:
https://doaj.org/article/992af03f02f647a1ada7ec843cd8c45d
Autor:
Makoto Nishimori, Naomi Hayasaka, Kazunori Otsui, Nobutaka Inoue, Junko Asakura, Manabu Nagao, Ryuji Toh, Tatsuro Ishida, Ken-ichi Hirata, Tomoyuki Furuyashiki, Masakazu Shinohara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Stress has garnered significant attention as a prominent risk factor for inflammation-related diseases, particularly cardiovascular diseases (CVDs). However, the precise mechanisms underlying stress-driven CVDs remain elusive, thereby impedi
Externí odkaz:
https://doaj.org/article/87b82116fc46422dbb4882fe053c3956
Autor:
Tetsuya Yamamoto, Hiroyuki Kawamori, Takayoshi Toba, Satoru Sasaki, Hiroyuki Fujii, Tomoyo Hamana, Yuto Osumi, Seigo Iwane, Shota Naniwa, Yuki Sakamoto, Koshi Matsuhama, Yuta Fukuishi, Ken‐ichi Hirata, Hiromasa Otake
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)
Background Perivascular inflammation contributes to the development of atherosclerosis and microcirculatory dysfunction. Pericoronary adipose tissue (PCAT) attenuation, measured by coronary computed tomography angiography, is a potential indicator of
Externí odkaz:
https://doaj.org/article/a05ca4e71efa4dafb9601cbab30d2b86
Autor:
Kenji Murakami, Towa Matsunaga, Takashi Matsuzaki, Yuta Naruke, Sonoko Miyauchi, Sota Kobayashi, Syuji Yoneyama, Yusuke Sakai, Toshihiro Ichijo, Toh-Ichi Hirata, Atsushi Kimura, Yuzumi Chiba, Kei-Ich Matsuda, Shinji Yamada, Hirokazu Hikono
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0302868 (2024)
To identify a biomarker for the early diagnosis of enzootic bovine leukosis (EBL) caused by bovine leukemia virus (BLV), we investigated the expression of a microRNA, bta-miR-375, in cattle serum. Using quantitative reverse-transcriptase PCR analysis
Externí odkaz:
https://doaj.org/article/4f6a1a50855d429eaf6d796926d5e71b
Autor:
Jun‐ichi Noiri, Yu Taniguchi, Yu Izawa, Nobuyuki Saga, Kaori Kusakabe, Yu‐ichiro Koma, Ken‐ichi Hirata
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare and critical malignancy‐related disease characterized by acute progressive pulmonary hypertension (PH). In most cases of PTTM, the cancer can be diagnosed in advance. Identificati
Externí odkaz:
https://doaj.org/article/ff97113a28fe40bd900fb19cdc15754c