Zobrazeno 1 - 10
of 11
pro vyhledávání: '"To Uyen T. Do"'
Autor:
Monica Binaschi, Andrea Pellacani, Stefano Manzini, Christian Rohlff, Keith E. Wilson, Jonathan Terrett, Carmel M. Lynch, Michael Trang, Dee Aud, Rahel Awdew, Phuoc Huy Pham, James E. Ackroyd, Rachel L. Dusek, San Lin Lou, Nickolas Attanasio, Sudha Swaminathan, Uyen T. Do, Robert Boyd, Angelo Kaplan, Arnima Bisht, Joaquin Arribas, Cristina Bernadó Morales, Rosanna Manno, Rossana Bugianesi, Massimiliano Salerno, Daniela Bellarosa, Corrado Carrisi, Alessandro Bressan, Mario Bigioni, Alessio Fiascarelli, Giuseppe Merlino
Supplementary Table S1. Commercial tumor TMAs representing different solid tumor types. Supplementary Table S2. Summary of CD205 expression in human solid tumor types.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21cf7101ed534f43774d52ecead68615
https://doi.org/10.1158/1535-7163.22506906
https://doi.org/10.1158/1535-7163.22506906
Autor:
Monica Binaschi, Andrea Pellacani, Stefano Manzini, Christian Rohlff, Keith E. Wilson, Jonathan Terrett, Carmel M. Lynch, Michael Trang, Dee Aud, Rahel Awdew, Phuoc Huy Pham, James E. Ackroyd, Rachel L. Dusek, San Lin Lou, Nickolas Attanasio, Sudha Swaminathan, Uyen T. Do, Robert Boyd, Angelo Kaplan, Arnima Bisht, Joaquin Arribas, Cristina Bernadó Morales, Rosanna Manno, Rossana Bugianesi, Massimiliano Salerno, Daniela Bellarosa, Corrado Carrisi, Alessandro Bressan, Mario Bigioni, Alessio Fiascarelli, Giuseppe Merlino
Supplementary Figure S1. Representative images of IHC staining for CD205 in different human and cynomolgus tissues, obtained with 2 μg/ml of MEN1309/OBT076 at 20X and 10X magnification. 1) Human donor spleen; moderate to strong membranous/granular c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7f557e3c0b13a225056116161e1ea2
https://doi.org/10.1158/1535-7163.22506924
https://doi.org/10.1158/1535-7163.22506924
Autor:
Monica Binaschi, Andrea Pellacani, Stefano Manzini, Christian Rohlff, Keith E. Wilson, Jonathan Terrett, Carmel M. Lynch, Michael Trang, Dee Aud, Rahel Awdew, Phuoc Huy Pham, James E. Ackroyd, Rachel L. Dusek, San Lin Lou, Nickolas Attanasio, Sudha Swaminathan, Uyen T. Do, Robert Boyd, Angelo Kaplan, Arnima Bisht, Joaquin Arribas, Cristina Bernadó Morales, Rosanna Manno, Rossana Bugianesi, Massimiliano Salerno, Daniela Bellarosa, Corrado Carrisi, Alessandro Bressan, Mario Bigioni, Alessio Fiascarelli, Giuseppe Merlino
Supplementary Table S5: Microscopic IHC staining for CD205 in different cynomolgus tissues after treatment with MEN1309/OBT076. Staining: 1, minimal (+, rare cells with low staining intensity); 2, slight/moderate (++, many cells with medium/high stai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d120dff76a7a69bed3c4755b84293b6
https://doi.org/10.1158/1535-7163.22506909.v1
https://doi.org/10.1158/1535-7163.22506909.v1
Autor:
Monica Binaschi, Andrea Pellacani, Stefano Manzini, Christian Rohlff, Keith E. Wilson, Jonathan Terrett, Carmel M. Lynch, Michael Trang, Dee Aud, Rahel Awdew, Phuoc Huy Pham, James E. Ackroyd, Rachel L. Dusek, San Lin Lou, Nickolas Attanasio, Sudha Swaminathan, Uyen T. Do, Robert Boyd, Angelo Kaplan, Arnima Bisht, Joaquin Arribas, Cristina Bernadó Morales, Rosanna Manno, Rossana Bugianesi, Massimiliano Salerno, Daniela Bellarosa, Corrado Carrisi, Alessandro Bressan, Mario Bigioni, Alessio Fiascarelli, Giuseppe Merlino
Supplementary Figure S3-A. Representative image of IHC staining for CD205 in a tumor mass from HCC-70 xenograft model, 16 days far from the initial treatment with 5 mg/kg of MEN1309/OBT076. The semiquantitative IHC analysis showed a score of 1+ in 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409b3e8ea4192c7e05c7ae7eb15f6146
https://doi.org/10.1158/1535-7163.22506918
https://doi.org/10.1158/1535-7163.22506918
Autor:
Monica Binaschi, Andrea Pellacani, Stefano Manzini, Christian Rohlff, Keith E. Wilson, Jonathan Terrett, Carmel M. Lynch, Michael Trang, Dee Aud, Rahel Awdew, Phuoc Huy Pham, James E. Ackroyd, Rachel L. Dusek, San Lin Lou, Nickolas Attanasio, Sudha Swaminathan, Uyen T. Do, Robert Boyd, Angelo Kaplan, Arnima Bisht, Joaquin Arribas, Cristina Bernadó Morales, Rosanna Manno, Rossana Bugianesi, Massimiliano Salerno, Daniela Bellarosa, Corrado Carrisi, Alessandro Bressan, Mario Bigioni, Alessio Fiascarelli, Giuseppe Merlino
Supplementary Figure S2. In vitro characterization of MEN1309/OBT076. A) ELISA assay showed that both the unconjugated and DM4-conjugated antibodies were able to bind FcγRIIIA with the same affinity (n=2). B) FACS binding experiment on THP-1 cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aefead13cb4ceb92f11fcd09e2c2c30
https://doi.org/10.1158/1535-7163.22506921.v1
https://doi.org/10.1158/1535-7163.22506921.v1
Autor:
Monica Binaschi, Andrea Pellacani, Stefano Manzini, Christian Rohlff, Keith E. Wilson, Jonathan Terrett, Carmel M. Lynch, Michael Trang, Dee Aud, Rahel Awdew, Phuoc Huy Pham, James E. Ackroyd, Rachel L. Dusek, San Lin Lou, Nickolas Attanasio, Sudha Swaminathan, Uyen T. Do, Robert Boyd, Angelo Kaplan, Arnima Bisht, Joaquin Arribas, Cristina Bernadó Morales, Rosanna Manno, Rossana Bugianesi, Massimiliano Salerno, Daniela Bellarosa, Corrado Carrisi, Alessandro Bressan, Mario Bigioni, Alessio Fiascarelli, Giuseppe Merlino
CD205 is a type I transmembrane glycoprotein and is a member of the C-type lectin receptor family. Analysis by mass spectrometry revealed that CD205 was robustly expressed and highly prevalent in a variety of solid malignancies from different histoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15a43cd253373afbccb5590a5dc6f77f
https://doi.org/10.1158/1535-7163.c.6538521.v1
https://doi.org/10.1158/1535-7163.c.6538521.v1
Autor:
Monica Binaschi, Andrea Pellacani, Stefano Manzini, Christian Rohlff, Keith E. Wilson, Jonathan Terrett, Carmel M. Lynch, Michael Trang, Dee Aud, Rahel Awdew, Phuoc Huy Pham, James E. Ackroyd, Rachel L. Dusek, San Lin Lou, Nickolas Attanasio, Sudha Swaminathan, Uyen T. Do, Robert Boyd, Angelo Kaplan, Arnima Bisht, Joaquin Arribas, Cristina Bernadó Morales, Rosanna Manno, Rossana Bugianesi, Massimiliano Salerno, Daniela Bellarosa, Corrado Carrisi, Alessandro Bressan, Mario Bigioni, Alessio Fiascarelli, Giuseppe Merlino
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eec59be317dbf0230532db78f737319
https://doi.org/10.1158/1535-7163.22506927
https://doi.org/10.1158/1535-7163.22506927
Autor:
Monica Binaschi, Andrea Pellacani, Stefano Manzini, Christian Rohlff, Keith E. Wilson, Jonathan Terrett, Carmel M. Lynch, Michael Trang, Dee Aud, Rahel Awdew, Phuoc Huy Pham, James E. Ackroyd, Rachel L. Dusek, San Lin Lou, Nickolas Attanasio, Sudha Swaminathan, Uyen T. Do, Robert Boyd, Angelo Kaplan, Arnima Bisht, Joaquin Arribas, Cristina Bernadó Morales, Rosanna Manno, Rossana Bugianesi, Massimiliano Salerno, Daniela Bellarosa, Corrado Carrisi, Alessandro Bressan, Mario Bigioni, Alessio Fiascarelli, Giuseppe Merlino
Supplementary Table S4: Antitumor activity of MEN1309/OBT076 on xenograft and PDX models with different CD205 antigen expression. a) PDX models.b) Score indicate the staining intensity. HE = heterogeneous. HO = homogeneous. c) TVI%, tumor volume inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357e39fb6df543e8129da435d88ab95d
https://doi.org/10.1158/1535-7163.22506912.v1
https://doi.org/10.1158/1535-7163.22506912.v1
Autor:
Giuseppe Merlino, Alessio Fiascarelli, Mario Bigioni, Alessandro Bressan, Corrado Carrisi, Daniela Bellarosa, Massimiliano Salerno, Rossana Bugianesi, Rosanna Manno, Cristina Bernadó Morales, Joaquin Arribas, Arnima Bisht, Angelo Kaplan, Robert Boyd, Uyen T. Do, Sudha Swaminathan, Nickolas Attanasio, San Lin Lou, Rachel L. Dusek, James E. Ackroyd, Phuoc Huy Pham, Rahel Awdew, Dee Aud, Michael Trang, Carmel M. Lynch, Jonathan Terrett, Keith E. Wilson, Christian Rohlff, Stefano Manzini, Andrea Pellacani, Monica Binaschi
Publikováno v:
Molecular Cancer Therapeutics. 18:1533-1543
CD205 is a type I transmembrane glycoprotein and is a member of the C-type lectin receptor family. Analysis by mass spectrometry revealed that CD205 was robustly expressed and highly prevalent in a variety of solid malignancies from different histoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c2ad62495f674c64e1af852341e07f
https://doi.org/10.1158/1535-7163.mct-18-0624
https://doi.org/10.1158/1535-7163.mct-18-0624
Autor:
To Uyen T. Do, Arnima Bisht, Nickolas Attanasio, San Lin Lou, Rachel L. Dusek, Robert Boyd, Gleb Feldman, Sudha Swaminathan, Christian Rohlff, Angelo Kaplan, Jason D. Allen, James Edward Ackroyd
Publikováno v:
Cancer Research. 78:2772-2772
The promise of immunotherapy for cancer is underscored by the recent efficacy of checkpoint inhibitors, which hinder the ability of tumors to escape attack by the immune system. Patients most likely to benefit from such therapy include those whose tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a74366426ac25baea1f131bdae01e44f
https://doi.org/10.1158/1538-7445.am2018-2772
https://doi.org/10.1158/1538-7445.am2018-2772