Zobrazeno 1 - 10
of 131 395
pro vyhledávání: '"Tnf-a"'
Autor:
Paul Stammer, Inka Terhorst, Jiangang Guo, Abdulhakim Ibrahim, Alexander Oberhuber, Thorsten Eierhoff
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract VE-cadherin (VEC) is a major endothelial adhesion protein, which controls vascular homeostasis. During vascular diseases, VEC can be shed from the endothelial surface by proteases like ADAM10/17, which cleave the extracellular domain of VEC
Externí odkaz:
https://doaj.org/article/a01d9cc32e6b4bad9fe0298f81526ee7
Autor:
Valentina Salvi, Carolina Gaudenzi, Barbara Mariotti, Gaia Giongrandi, Silvia Alacqua, Veronica Gianello, Tiziana Schioppa, Laura Tiberio, Angela Ceribelli, Carlo Selmi, Paolo Bergese, Stefano Calza, Annalisa Del Prete, Silvano Sozzani, Flavia Bazzoni, Daniela Bosisio
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background The physiological relevance of cell-to-cell communication mediated by small extracellular vesicle-encapsulated microRNAs (sEV-miRNAs) remains debated because of the limiting representativity of specific miRNAs within the extracell
Externí odkaz:
https://doaj.org/article/314b902687d6416e8812b09c4914d5db
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 12, Iss 6, Pp 1178-1186 (2024)
Context: Doxorubicin is an anticancer drug that can adversely affect the liver. Therefore, seeking medical attention to manage pain and minimize side effects is crucial. Aims: To evaluate the hepatoprotective potential of Vitis gracilis Wall. nano
Externí odkaz:
https://doaj.org/article/a845524c45d2467b99a99ebd1396c622
Publikováno v:
BioResources, Vol 19, Iss 4, Pp 9220-9233 (2024)
Wound repair is the practice of repairing the skin and other soft tissues after an injury. An inflammatory response is activated after an injury, and cells below the dermis (deepest skin layer) begin to produce more collagen (connective tissue). A sc
Externí odkaz:
https://doaj.org/article/ec7a0fff20514371b6b8bf025f1837db
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Pyroptosis is a gasdermin-mediated pro-inflammatory form of programmed cell death (PCD). Tumor necrosis factor-ɑ (TNF-ɑ) is an inflammatory cytokine, and some studies have shown that TNF-ɑ can cause pyroptosis of cells and exert anti-tumo
Externí odkaz:
https://doaj.org/article/726ec2d2f8ba406e998d642707c28710
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-12 (2024)
Abstract Objective Accumulation of extracellular matrix (ECM) proteins in the glomerular mesangial region is a typical hallmark of diabetic nephropathy (DN). However, the molecular mechanism underlying ECM accumulation in the mesangium of DN patients
Externí odkaz:
https://doaj.org/article/b7de771b463746229504589422e7b003
Autor:
Faustina Adu, Ebenezer Aniakwaa-Bonsu, Samuel Badu Nyarko, Aikins Sarpong Obeng, Richmond Owusu Ateko, Akwasi Anyanful, Nicholas Ekow Thomford
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Hepatitis B virus (HBV) infection is a public health concern in resource limited settings like Ghana. Over the past decades, it is noted that the natural course of HBV in persons infected are taking a worse turn leading to liver c
Externí odkaz:
https://doaj.org/article/aac4b8181da14e938ec159826c689868
Autor:
Huiqian Yuan, Yingying Li, Xianlin Liu, Langjun Su, Qiping Li, Chunhong Yang, Chao Chen, Chunyang Li
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Olfactory function is closely related to mood and the endocrine system. However, the role of olfactory function in bipolar disorder combined with metabolic syndrome remains unclear. The purpose of this study was to explore the ass
Externí odkaz:
https://doaj.org/article/1de6ddc1ffc2448f94f9fe618d6f00db
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 10, Pp 916-925 (2024)
Abstract This study aims to investigate the effects of the Galectin‐3 (Gal‐3) inhibitor TD139 on inflammation and the extracellular signal‐regulated kinase (ERK)/c‐Jun N‐terminal kinase (JNK)/p38 pathway in gestational diabetes mellitus (GD
Externí odkaz:
https://doaj.org/article/88cb4030263f4b4e9532d24708230ad7
Autor:
Maja Pantovic-Stefanovic, Milica Velimirovic, Vladimir Jurisic, Marija Puric, Marta Gostiljac, Sara Dodic, Ivana Minic, Milica Nesic, Tatjana Nikolic, Natasa Petronijevic, Maja Ivkovic, Bojana Dunjic-Kostic
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Psychotic and mood disorders are discussed as part of the same continuum. The potential role of immune dysregulation in defining their clinical presentations, however, remains unclear. Differences in TNF-α, IL-6 and TGF-β levels were inves
Externí odkaz:
https://doaj.org/article/312bfe48f3914c25b23b45a62b53c8c1