Zobrazeno 1 - 10
of 447
pro vyhledávání: '"Tn3 transposon"'
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Hypervirulent and carbapenem-resistant Klebsiella pneumoniae poses a severe threat to public health for its high pathogenicity, transmissibility, and drug resistance. This study aims to explore the evolutionary path and the role of Tn3 trans
Externí odkaz:
https://doaj.org/article/e7e83dc197ef4c06b66869129da2b91d
Akademický článek
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Publikováno v:
Nucleic Acids Research
Homologous recombination forms and resolves an entangled DNA Holliday Junction (HJ) crucial for achieving genetic reshuffling and genome repair. To maintain genomic integrity, specialized resolvase enzymes cleave the entangled DNA into two discrete D
Publikováno v:
Molecular Genetics and Genomics. 296:551-559
The genus Habenivirus which includes Ralstonia virus ϕRSM encodes a site-specific integrase of a small serine recombinase belonging to the resolvase/invertase family. Here we describe the integrative/excisive recombination reactions mediated by ϕRS
Publikováno v:
Molecular Microbiology. 114:952-965
The site-specific recombinase Tn3 resolvase initiates DNA strand exchange when two res recombination sites and six resolvase dimers interact to form a synapse. The detailed architecture of this intricate recombination machine remains unclear. We have
Publikováno v:
Genome Instability & Disease. 1:184-196
Homologous recombination (HR) repairs double-strand breaks (DSBs) occurring in sister chromatids using the intact sisters as the repair template. HR is initiated by DSB resection, which generates 3′ single-strand DNA (ssDNA). RAD51 recombinase poly
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications
Holliday junctions (HJs) are key DNA intermediates in genetic recombination and are eliminated by nuclease, termed resolvase, to ensure genome stability. HJ resolvases have been identified across all kingdoms of life, members of which exhibit sequenc
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Fowlpox virus resolvase (Fpr) is an endonuclease that cleaves a broad range of branched DNA structures, including the Holliday junction (HJ), with little sequence-specificity. To better understand the mechanisms underlying its relaxed substrate speci
Publikováno v:
Microorganisms, Vol 9, Iss 1926, p 1926 (2021)
Microorganisms
Volume 9
Issue 9
Microorganisms
Volume 9
Issue 9
Resistance of bacteria to 3rd generation cephalosporins mediated by beta-lactamases (ESBL, pAmpC) is a public health concern. In this study, 1517 phenotypically cephalosporin-resistant E. coli were screened for the presence of blaSHV genes. Respectiv
Autor:
Lukasz eDziewit, Adam ePyzik, Magdalena eSzuplewska, Renata eMatlakowska, Sebastian eMielnicki, Daniel eWibberg, Andreas eSchlüter, Alfred ePühler, Dariusz eBartosik
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
The Lubin underground mine, is one of three mining divisions in the Lubin-Glogow Copper District in Lower Silesia province (Poland). It is the source of polymetallic ore that is rich in copper, silver and several heavy metals. Black shale is also sig
Externí odkaz:
https://doaj.org/article/67498e52e80e445e84be4523d21088d5