Zobrazeno 1 - 10
of 11 168
pro vyhledávání: '"Tlr"'
Autor:
O. A. Svitich, O. Yu. Olisova, M. B. Potapova, E. A. Meremianina, N. D. Rasskazova, E. A. Belokopytova, A. A. Solodkova, A. A. Murzina, I. B. Semenova, A. G. Upatova
Publikováno v:
Медицинская иммунология, Vol 26, Iss 6, Pp 1249-1256 (2024)
Atopic dermatitis (AD) is a chronic recurrent inflammatory disease accompanied by severe itching. One of the leading mechanisms underlying the development of AD is an imbalance of the Th1/Th2 cells immune response, which leads to an increased product
Externí odkaz:
https://doaj.org/article/351184a1abf040d199e36e0f8afbef42
Autor:
Ava Hashempour, Nastaran Khodadad, Shokufeh Akbarinia, Farzane Ghasabi, Younes Ghasemi, Mohamad Matin Karbalaei Ali Nazar, Shahab Falahi
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-21 (2024)
Abstract Substantial advances have been made in the development of promising HIV vaccines to eliminate HIV-1 infection. For the first time, one hundred of the most submitted HIV subtypes and CRFs were retrieved from the LANL database, and the consens
Externí odkaz:
https://doaj.org/article/568d3dd8ab2541b1904b2f1ba88487b4
Publikováno v:
Forbes Tıp Dergisi, Vol 5, Iss 2, Pp 116-122 (2024)
Objective: Oral lichen planus (OLP) is a chronic oral mucosal disease of unknown etiology. Cellular immune response, basement membrane, and extracellular matrix (ECM) molecules are also noteworthy in the pathogenesis. We aimed to investigate the role
Externí odkaz:
https://doaj.org/article/d9ba0ce468f24ab9b55d05829eec89e1
Autor:
A. B. Pyatidesyatnikova, V. I. Dubrovina, O. V. Yurieva, K. M. Korytov, T. I. Ivanova, V. A. Potapov, M. V. Musalov, S. V. Balakhonov
Publikováno v:
Acta Biomedica Scientifica, Vol 9, Iss 3, Pp 249-255 (2024)
One of the important directions for increasing the immunogenic properties of vaccine strains against highly dangerous infections is the search for adjuvants that not only stimulate the immunological effectiveness of vaccination, but can also provide
Externí odkaz:
https://doaj.org/article/fbe730a5c8b64b8faaecb57c014eea27
Publikováno v:
Stresses, Vol 4, Iss 3, Pp 411-420 (2024)
Stress granules (SGs) are cytoplasmic membraneless compartments that can form in stressed cells. There is an intricate relationship between SGs and innate immune signaling pathways. A previous study reported that the innate immune signaling mediated
Externí odkaz:
https://doaj.org/article/d0569bc0618646e5a4cb8b15e5c38dee
Autor:
A. N. Narovlyansky, V. V. Poloskov, M. V. Mezentseva, I. A. Suetina, A. V. Tsvetnov, E. Yu. Bogdanov, I. T. Fedyakina, A. L. Kovalenko, F. I. Ershov
Publikováno v:
Медицинская иммунология, Vol 26, Iss 4, Pp 663-670 (2024)
Activation of Toll-like receptors (TLRs) is one of the earliest indicators of functional activation of the innate immune system. Therefore, the development of drugs that stimulate the transcription of TLR/RLR genes and at the same time are “multi-t
Externí odkaz:
https://doaj.org/article/5dc1636eb40f4efea9aa9fc6682a3bea
Autor:
Mohammadreza Kosari, Afsaneh Asgari Taei, Andis Klegeris, Sevim Soleimani, Arian Tavasol, Kimia Jazi, Kimia Eyvani, Ashkan Bahrami, Zahra Farrokhi, Farnoosh Vosough, Faraz Rahmani Khajeh, Saleh Behzadi, Zohreh Zamani
Publikováno v:
Caspian Journal of Neurological Sciences, Vol 10, Iss 3, Pp 151-168 (2024)
Background: Parkinson disease (PD) is a prevalent neurodegenerative disorder affecting dopaminergic neurons in the substantia nigra (SN). Neuroinflammation has a vital role in PD pathophysiology. Objectives: This study assesses whether the neuroinfla
Externí odkaz:
https://doaj.org/article/ee898c1994754acd8687184871d600e5
Autor:
Sandrine Juillard, Annie Karakeussian-Rimbaud, Marie-Hélène Normand, Julie Turgeon, Charlotte Veilleux-Trinh, Alexa C. Robitaille, Joyce Rauch, Andrzej Chruscinski, Nathalie Grandvaux, Éric Boilard, Marie-Josée Hébert, Mélanie Dieudé
Publikováno v:
Journal of Translational Autoimmunity, Vol 9, Iss , Pp 100250- (2024)
According to a central tenet of classical immune theory, a healthy immune system must avoid self-reactive lymphocyte clones but we now know that B cells repertoire exhibit some level of autoreactivity. These autoreactive B cells are thought to rely o
Externí odkaz:
https://doaj.org/article/3f413fb29e1b49bb99f06fa8ba30c686
Autor:
Francois Xavier Rwandamuriye, Tao Wang, Hanfu Zhang, Omar Elaskalani, Jorren Kuster, Xueting Ye, Breana Vitali, Juliët Schreurs, M. Lizeth Orozco Morales, Marck Norret, Cameron W. Evans, Rachael M. Zemek, K. Swaminathan Iyer, W. Joost Lesterhuis, Ben Wylie
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Toll-like receptor (TLR) agonists are being developed as anti-cancer therapeutics due to their potent immunostimulatory properties. However, clinical trials testing TLR agonists as monotherapy have often failed to demonstrate significant improvement
Externí odkaz:
https://doaj.org/article/2a3718095d18493b9813cd62cb6972ec