Development of NR0B2 as a therapeutic target for the re-education of tumor associated myeloid cells.

Autor: Vidana Gamage HE; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Albright ST; Department of Chemistry, University of Illinois at Urbana-Champaign, Illinois, USA., Smith AJ; Department of Chemistry, University of Illinois at Urbana-Champaign, Illinois, USA., Farmer R; Department of Chemistry, University of Illinois at Urbana-Champaign, Illinois, USA., Shahoei SH; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Wang Y; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Fink EC; Department of Cancer Biology, Loyola University Chicago Health Sciences Campus, Illinois, USA., Jacquin E; INSERM, U1231, Dijon, France., Weisser E; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Bautista RO; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Henn MA; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Schane CP; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Nelczyk AT; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Ma L; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Das Gupta A; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Bendre SV; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Nguyen T; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Tiwari S; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Krawczynska N; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Illinois, USA., He S; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Tjoanda E; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Chen H; Food Science & Human Nutrition, University of Illinois at Urbana-Champaign, Illinois, USA., Sverdlov M; Research Histology and Tissue Imaging Core, University of Illinois at Chicago, Illinois, USA., Gann PH; Research Histology and Tissue Imaging Core, University of Illinois at Chicago, Illinois, USA; Department of Pathology, University of Illinois at Chicago, Illinois, USA., Boidot R; Unit of Molecular Biology, Department of Biology and Pathology of Tumors, Georges-Francois Leclerc Cancer Center, Dijon, France; ICMUB UMR CNRS 6302, Dijon, France., Vegran F; INSERM, U1231, Dijon, France., Fanning SW; Department of Cancer Biology, Loyola University Chicago Health Sciences Campus, Illinois, USA., Apetoh L; INSERM, U1231, Dijon, France., Hergenrother PJ; Department of Chemistry, University of Illinois at Urbana-Champaign, Illinois, USA; Carl R. Woese Institute for Genomic Biology- Anticancer Discovery from Pets to People, University of Illinois at Urbana-Champaign, Illinois, USA; Cancer Center at Illinois, University of Illinois Urbana-Champaign, University of Illinois at Urbana-Champaign, Illinois, USA., Nelson ER; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Illinois, USA; Carl R. Woese Institute for Genomic Biology- Anticancer Discovery from Pets to People, University of Illinois at Urbana-Champaign, Illinois, USA; Cancer Center at Illinois, University of Illinois Urbana-Champaign, University of Illinois at Urbana-Champaign, Illinois, USA; Division of Nutritional Sciences, University of Illinois Urbana-Champaign, University of Illinois at Urbana-Champaign, Illinois, USA. Electronic address: enels@illinois.edu.

Publikováno v: Cancer letters [Cancer Lett] 2024 Aug 10; Vol. 597, pp. 217086. Date of Electronic Publication: 2024 Jun 27.

Re-education of myeloid immune cells to reduce regulatory T cell expansion and impede breast cancer progression.

Autor: Gamage HEV; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Shahoei SH; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Albright ST; Department of Chemistry, University of Illinois at Urbana-Champaign, Illinois, USA., Wang Y; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Smith AJ; Department of Chemistry, University of Illinois at Urbana-Champaign, Illinois, USA., Farmer R; Department of Chemistry, University of Illinois at Urbana-Champaign, Illinois, USA., Fink EC; Department of Cancer Biology, Loyola University Chicago Health Sciences Campus, Illinois, USA., Jacquin E; INSERM, U1231, Dijon, France., Weisser E; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Bautista RO; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Henn MA; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Schane CP; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Nelczyk AT; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Ma L; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Gupta AD; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Bendre SV; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Nguyen T; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Tiwari S; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Krawczynska N; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA.; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Illinois, USA., He S; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Tjoanda E; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA., Chen H; Food Science & Human Nutrition, University of Illinois at Urbana-Champaign, Illinois, USA., Sverdlov M; Research Histology and Tissue Imaging Core, University of Illinois at Chicago, Illinois, USA., Gann PH; Research Histology and Tissue Imaging Core, University of Illinois at Chicago, Illinois, USA.; Department of Pathology, University of Illinois at Chicago, Illinois, USA., Boidot R; Unit of Molecular Biology, Department of Biology and Pathology of Tumors, Georges-Francois Leclerc cancer Center, Dijon, France, and ICMUB UMR CNRS 6302, Dijon, France., Vegran F; INSERM, U1231, Dijon, France., Fanning SW; Department of Cancer Biology, Loyola University Chicago Health Sciences Campus, Illinois, USA., Apetoh L; INSERM, U1231, Dijon, France., Hergenrother PJ; Department of Chemistry, University of Illinois at Urbana-Champaign, Illinois, USA.; Carl R. Woese Institute for Genomic Biology- Anticancer Discovery from Pets to People, University of Illinois at Urbana-Champaign, Illinois, USA.; Cancer Center at Illinois, University of Illinois Urbana-Champaign, University of Illinois at Urbana-Champaign, Illinois, USA., Nelson ER; Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Illinois, USA.; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Illinois, USA.; Carl R. Woese Institute for Genomic Biology- Anticancer Discovery from Pets to People, University of Illinois at Urbana-Champaign, Illinois, USA.; Cancer Center at Illinois, University of Illinois Urbana-Champaign, University of Illinois at Urbana-Champaign, Illinois, USA.; Division of Nutritional Sciences, University of Illinois Urbana-Champaign, University of Illinois at Urbana-Champaign, Illinois, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Aug 14. Date of Electronic Publication: 2023 Aug 14.