Combined Transcriptome Sequencing of Mycoplasma hyopneumoniae and Infected Pig Lung Tissue Reveals Up-Regulation of Bacterial F1-Like ATPase and Down-Regulation of the P102 Cilium Adhesin in vivo

Autor: Tjerko Kamminga, Nirupama Benis, Vitor Martins dos Santos, Jetta J. E. Bijlsma, Peter J. Schaap

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

Mycoplasma hyopneumoniae (M. hyopneumoniae) causes enzootic pneumonia in pigs but it is still largely unknown which host-pathogen interactions enable persistent infection and cause disease. In this study, we analyzed the host and bacterial transcript

Externí odkaz: https://doaj.org/article/1858d115d0cb445f8e9e9fb5600cb100

Risk-Based Bioengineering Strategies for Reliable Bacterial Vaccine Production

Autor: Peter J. Schaap, Vitor A. P. Martins dos Santos, Jetta J. E. Bijlsma, Tjerko Kamminga, Simen Jan Slagman

Publikováno v: Trends in Biotechnology, 37(8), 805-816
Trends in Biotechnology 37 (2019) 8
Trends in Biotechnology

Design of a reliable process for bacterial antigen production requires understanding of and control over critical process parameters. Current methods for process design use extensive screening experiments for determining ranges of critical process pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ab8762f95672fe4647eee94f18bd01
https://research.wur.nl/en/publications/risk-based-bioengineering-strategies-for-reliable-bacterial-vacci

Bacterial antisense RNAs are mainly the product of transcriptional noise

Autor: Amparo Latorre, Luis Serrano, John I. Glass, Verónica Lloréns-Rico, Maria Lluch-Senar, Tjerko Kamminga, Jaime González Cano, Wei-Hua Chen, Rosario Gil, Peer Bork

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Science Advances
Science advances
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Science Advances 2 (2016) 3
r-FISABIO. Repositorio Institucional de Producción Científica
Science Advances, 2(3)

Most of the antisense transcripts in bacteria are the product of transcriptional noise derived from spurious promoters.
cis-Encoded antisense RNAs (asRNAs) are widespread along bacterial transcriptomes. However, the role of most of these RNAs re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b26b89f3e3f0a3b05661028878819d2