Immunochemical detection of group I and group II phospholipases A2 in human serum

Autor: Tj, Nevalainen, Pt, Kortesuo, Esa Rintala, Märki F

Publikováno v: Europe PubMed Central

Time-resolved fluoroimmunoassay was developed for the detection of synovial-type phospholipase A2 (s-PLA2) in human serum. This solid-phase, sandwich assay uses a polyclonal rabbit antibody raised against synovial-type group II PLA2 produced in Esche

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::64a41b2eac6d20b90220a81f7e75f82f
https://pubmed.ncbi.nlm.nih.gov/1526020

CB 2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells.

Autor: Hytti M; School of Pharmacy, University of Eastern Finland, Kuopio, Finland. maria.hytti@uef.fi.; Department of Ophthalmology, School of Medicine, University of Eastern Finland, Kuopio, Finland. maria.hytti@uef.fi., Andjelic S; Eye Hospital, University Medical Centre, Ljubljana, Slovenia., Josifovska N; Stem Cells and Eye Research Laboratory, Department of Ophthalmology, Faculty of Medicine, University of Szeged, Szeged, Hungary., Piippo N; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.; Department of Ophthalmology, School of Medicine, University of Eastern Finland, Kuopio, Finland., Korhonen E; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.; Department of Ophthalmology, School of Medicine, University of Eastern Finland, Kuopio, Finland., Hawlina M; Eye Hospital, University Medical Centre, Ljubljana, Slovenia., Kaarniranta K; Department of Ophthalmology, School of Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Ophthalmology, Kuopio University Hospital, Kuopio, Finland., Nevalainen TJ; School of Pharmacy, University of Eastern Finland, Kuopio, Finland., Petrovski G; Stem Cells and Eye Research Laboratory, Department of Ophthalmology, Faculty of Medicine, University of Szeged, Szeged, Hungary.; Centre of Eye Research, Department of Ophthalmology and the Norwegian Center for Stem Cell Research, Oslo University Hospital, University of Oslo, Oslo, Norway., Parkkari T; School of Pharmacy, University of Eastern Finland, Kuopio, Finland., Kauppinen A; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.

Publikováno v: Scientific reports [Sci Rep] 2017 Nov 23; Vol. 7 (1), pp. 16169. Date of Electronic Publication: 2017 Nov 23.

Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human α/β-hydrolase domain containing 11 (ABHD11).

Autor: Navia-Paldanius D; School of Medicine, Institute of Biomedicine, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland. Electronic address: dina.navia-paldanius@uef.fi., Patel JZ; School of Pharmacy, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland., López Navarro M; School of Medicine, Institute of Biomedicine, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland., Jakupović H; School of Medicine, Institute of Biomedicine, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland., Goffart S; Department of Biology, University of Eastern Finland, P.O Box 111, 80101 Joensuu, Finland., Pasonen-Seppänen S; School of Medicine, Institute of Biomedicine, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland., Nevalainen TJ; School of Pharmacy, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland., Jääskeläinen T; School of Medicine, Institute of Biomedicine, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland; Institute of Dentistry, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland., Laitinen T; School of Pharmacy, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland., Laitinen JT; School of Medicine, Institute of Biomedicine, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland., Savinainen JR; School of Medicine, Institute of Biomedicine, University of Eastern Finland, P.O Box 1627, 70211 Kuopio, Finland.

Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2016 Oct 10; Vol. 93, pp. 253-63. Date of Electronic Publication: 2016 Aug 17.

Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists.

Autor: Yrjölä S; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland. Electronic address: sari.yrjola@uef.fi., Parkkari T; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland; Institute of Biomedicine, School of Medicine, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland., Navia-Paldanius D; Institute of Biomedicine, School of Medicine, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland., Laitinen T; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland., Kaczor AA; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Lab, Faculty of Pharmacy with Division of Medical Analytics, Medical University of Lublin, 4A Chodzki St., PL-20093 Lublin, Poland., Kokkola T; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland., Adusei-Mensah F; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland., Savinainen JR; Institute of Biomedicine, School of Medicine, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland., Laitinen JT; Institute of Biomedicine, School of Medicine, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland., Poso A; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland; Division of Translational Gastrointestinal Oncology, Dept. of Internal Medicine I, University Hospital Tübingen, Otfried-Mueller-Strasse 10, 72076 Tübingen, Germany., Alexander A; Division of Neuroscience, Medical Research Institute, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, UK., Penman J; Division of Neuroscience, Medical Research Institute, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, UK., Stott L; Division of Neuroscience, Medical Research Institute, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, UK., Anskat M; Division of Neuroscience, Medical Research Institute, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, UK., Irving AJ; Division of Neuroscience, Medical Research Institute, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, UK; School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin D4, Ireland., Nevalainen TJ; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, PO Box 1627, FI-70211 Kuopio, Finland.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2016 Jan 01; Vol. 107, pp. 119-32. Date of Electronic Publication: 2015 Nov 02.

Comparative molecular field analysis and molecular dynamics studies of α/β hydrolase domain containing 6 (ABHD6) inhibitors.

Autor: Kaczor AA; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Molecular Modeling Laboratory, Faculty of Pharmacy with Division of Medical Analytics, Medical University of Lublin, 4a Chodźki St., 20059, Lublin, Poland, agnieszka.kaczor@umlub.pl., Targowska-Duda KM, Patel JZ, Laitinen T, Parkkari T, Adams Y, Nevalainen TJ, Poso A

Publikováno v: Journal of molecular modeling [J Mol Model] 2015 Oct; Vol. 21 (10), pp. 250. Date of Electronic Publication: 2015 Sep 08.