Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tiziano Zanelli"'
Autor:
Gianfranco Caselli, Albino Bonazzi, Marco Lanza, Flora Ferrari, Daniele Maggioni, Cristian Ferioli, Roberto Giambelli, Eleonora Comi, Silvia Zerbi, Marco Perrella, Ornella Letari, Elena Di Luccio, Milena Colovic, Stefano Persiani, Tiziano Zanelli, Laura Mennuni, Tiziana Piepoli, Lucio Claudio Rovati
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-19 (2018)
Abstract Background Prostaglandin E2 (PGE2) acts via its EP4 receptor as a cytokine amplifier (e.g., interleukin [IL]-6) and induces the differentiation and expansion of inflammatory T-helper (Th) lymphocytes. These mechanisms play a key role in the
Externí odkaz:
https://doaj.org/article/22fc8ca4e2234150b60717587ab81196
Autor:
Riccardo Chiusaroli, Tiziana Piepoli, Tiziano Zanelli, Paola Ballanti, Marco Lanza, Lucio C. Rovati, Gianfranco Caselli
Publikováno v:
International Journal of Rheumatology, Vol 2011 (2011)
Several clinical studies demonstrated that glucosamine sulfate (GS) is effective in controlling osteoarthritis (OA), showing a structure-modifying action. However, little is known about the molecular mechanism(s) by which GS exerts such action and ab
Externí odkaz:
https://doaj.org/article/dc6e8535e88f49f38fb464382503d6c4
Autor:
Kanji Bhimani, Gianfranco Caselli, Sabrina Pucci, Luca Canciani, Cristian Ferioli, Tiziana Piepoli, Mehul Kaswala, Silvia Zerbi, Manuela Borriello, Tiziano Zanelli, Laura Mennuni, Luigi Piero Stasi, Matteo Salvi, Fabrizio Colace, Vikas Shirsath
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:6336-6340
The construction of a EP(4) antagonists pharmacophore model and the discovery of a highly potent oxepinic series of EP(4) antagonists is discussed. Compound 1a exhibits an excellent selectivity profile toward EP(2) receptor subtype and low cytochrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9e44d8000dd6e21652d2b3d1ec880c
https://doi.org/10.1016/j.bmcl.2011.08.102
https://doi.org/10.1016/j.bmcl.2011.08.102
Publikováno v:
European Journal of Pharmacology. 504:223-233
CR3465 (L-Tyrosine, N-[(2-quinolinyl)carbonyl]-O-(7-fluoro-2-quinolinylmethyl) sodium salt) is a potent antagonist of [3H]leukotriene D4 ([3H]LTD4) binding to guinea pig lung preparations, its Ki (4.7+/-0.7 nM) being comparable with that of monteluka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c0cb878415dbebdda1176d6b06a659
https://doi.org/10.1016/j.ejphar.2004.10.010
https://doi.org/10.1016/j.ejphar.2004.10.010
Publikováno v:
Scopus-Elsevier
Abstract —Oxidized low density lipoproteins (OxLDLs) are believed to play a central role in atherogenesis and to possess a wide variety of biological properties; among them, OxLDLs are cytotoxic to cultured vascular cells in that they induce necros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f9b70faef51efe9a1a093c6868578e
https://doi.org/10.1161/01.atv.21.3.348
https://doi.org/10.1161/01.atv.21.3.348
Publikováno v:
Biochemical and Biophysical Research Communications. 212:602-608
A full-length cDNA clone for human thyroid peroxidase inserted into the mammalian cell expression vector pECE was stably transfected into the rat thyroid cell line FRTL5. Clones expressed immunologically and enzymatically assessed human thyroid perox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a95ad1550e7cd769331b04f0a473f5
https://doi.org/10.1006/bbrc.1995.2012
https://doi.org/10.1006/bbrc.1995.2012
Autor:
Tiziano Zanelli, Tiziana Piepoli, Gianfranco Caselli, Lucio C. Rovati, R. Chiusaroli, Paola Ballanti, Marco Lanza
Publikováno v:
International Journal of Rheumatology, Vol 2011 (2011)
International Journal of Rheumatology
International Journal of Rheumatology
Several clinical studies demonstrated that glucosamine sulfate (GS) is effective in controlling osteoarthritis (OA), showing a structure-modifying action. However, little is known about the molecular mechanism(s) by which GS exerts such action and ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26fea28de854bffe02447dfddd1ea82e
Autor:
Francesca Ragogna, Alberico L. Catapano, Cristina Tettamanti, F. Viganò, Giacomo Ruotolo, M. Parlavecchia, Tiziano Zanelli
Publikováno v:
Atherosclerosis. 137(1)
Familial hypobetalipoproteinemia is an autosomal codominant trait that can be caused by mutations in the apo B gene. Here we report a novel apo B gene mutation causing hypobetalipoproteinemia, that is associated with the synthesis of a truncated apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c05d84b45dc3775b35e132d54d4a8c
https://pubmed.ncbi.nlm.nih.gov/9568744
https://pubmed.ncbi.nlm.nih.gov/9568744
Publikováno v:
Atherosclerosis. 130(1-2)
Control of apolipoprotein B (apo B) secretion in hepatocytes occurs partly at the post-translational level. The key step in this process appears to be intracellular degradation of newly synthesized apo B. The aim of this paper was to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc3a716308d211b0287b8e1085a125a
https://pubmed.ncbi.nlm.nih.gov/9126658
https://pubmed.ncbi.nlm.nih.gov/9126658
Autor:
Alberto Notarbartolo, Alberico L. Catapano, Carlo M. Barbagallo, Maurizio Averna, Fabio C. Giardina, Tiziano Zanelli, Andrea Liotta
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 224(2)
The apo C-II gene from a patient with apo C-II deficiency has been sequenced after amplification by the polymerase chain reaction (PCR). The sequence analysis revealed a substitution of adenosine for cytosine at position 3,002 in exon 3, leading to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881f2b9ee7f58356135e8c4a5332c91b
https://pubmed.ncbi.nlm.nih.gov/8004780
https://pubmed.ncbi.nlm.nih.gov/8004780