Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tiziana Spadafina"'
Autor:
Melita A Gordon, Ellis Owusu-Dabo, Florian Marks, Carsten Mantel, Andrew J Pollard, Brama Hanumunthadu, Rachel White, John A Crump, Hannah Robinson, Jan Jacobs, Samuel Kariuki, Bieke Tack, Stefano Malvolti, Nasir Kanji, Nelly Owino, Carla Ferreira Da Silva, Pietro Ferruzzi, Usman Nakakana, Rocio Canals, Maheshi Ramasamy, Francis Agyapong, Gianluca Breghi, Fabio Fiorino, Christian S. Marchello, Donata Medaglini, Esther M. Muthumbi, Chisomo L. Msefula, Tonney S. Nyirenda, Robert Onsare, Elena Pettini, Anthony G Scott J, Bassiahi Abdramane Soura, Tiziana Spadafina
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Introduction Invasive non-typhoidal Salmonellosis (iNTS) is mainly caused by Salmonella enterica serovars Typhimurium and Enteritidis and is estimated to result in 77 500 deaths per year, disproportionately affecting children under 5 years of age in
Externí odkaz:
https://doaj.org/article/7f29c2eaf5e042f4a8bfa23fb84777a2
Autor:
Sofia Orrskog, Samuli Rounioja, Tiziana Spadafina, Marilena Gallotta, Martin Norman, Karina Hentrich, Stefan Fälker, Sofia Ygberg-Eriksson, Mike Hasenberg, Björn Johansson, Liisa M. Uotila, Carl G. Gahmberg, Michèle Barocchi, Matthias Gunzer, Staffan Normark, Birgitta Henriques-Normark
Publikováno v:
mBio, Vol 4, Iss 1 (2013)
ABSTRACT Pneumococcal pili have been shown to influence pneumococcal colonization, disease development, and the inflammatory response in mice. The role of the pilus-associated RrgA adhesin in pneumococcal interactions with murine and human macrophage
Externí odkaz:
https://doaj.org/article/61bf47911139403a9c51ff45e75d9a80
PurposeThis study provides a systematic literature review and categorization of the costs reported in the literature for the introduction of new vaccines, focusing on sub-Saharan Africa within LMICs, where vaccines are highly needed, financial resour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d10759eb92d1dface0f1b77e5ccb447
https://hdl.handle.net/11365/1215094
https://hdl.handle.net/11365/1215094
Autor:
Bieke Tack, Bassiahi Abdramane Soura, Fabio Fiorino, Laura B. Martin, Rocío Canals, Robert S. Onsare, Ellis Owusu-Dabo, Stefano Malvolti, Melita A Gordon, John A. Crump, Christian S. Marchello, Elena Pettini, J. Anthony G. Scott, Samuel Kariuki, Brama Hanumunthadu, Jong-Hoon Kim, Jan Jacobs, Carsten Mantel, Gianluca Breghi, Florian Marks, M N Ramasamy, Vittal Mogasale, Donata Medaglini, Tonney Niyrenda, Michael Owusu, Tiziana Spadafina, Esther Muthumbi
Publikováno v:
The Journal of infection
SUMMARY Objectives : We sought to collate and summarize high-quality data on non-typhoidal Salmonella invasive disease (iNTS) incidence to provide contemporary incidence estimates by location and year. Methods : We systematically searched the databas
Autor:
Christian S Marchello, Megan Birkhold, John A Crump, Laura B. Martin, Michael O. Ansah, Gianluca Breghi, Rocio Canals, Fabio Fiorino, Melita A. Gordon, Jong-Hoon Kim, Mainga Hamaluba, Brama Hanumunthadu, Jan Jacobs, Samuel Kariuki, Stefano Malvolti, Carsten Mantel, Florian Marks, Donata Medaglini, Vittal Mogasale, Chisomo L. Msefula, Esther Muthumbi, Tonney S. Niyrenda, Robert Onsare, Ellis Owusu-Dabo, Elena Pettini, Maheshi N. Ramasamy, Bassiahi A. Soura, Tiziana Spadafina, Bieke Tack
Publikováno v:
The Lancet Infectious Diseases
BACKGROUND: Non-typhoidal salmonella can cause serious, life-threatening invasive infections involving the bloodstream and other normally sterile sites. We aimed to systematically review the prevalence of complications and case-fatality ratio (CFR) o
Autor:
Chiara Sammicheli, Sandra Nuti, Tiziana Spadafina, Silvia Maccari, Alessia Corrado, Donatello Laera, Paolo Donato, Fabio Bagnoli, Sylvie Bertholet, Bruno Galletti, Ennio De Gregorio, Emiliano Chiarot, Andrea G. O. Manetti, Letizia Arcidiacono, Anja Seubert, Raffaella Cecchi, Giuliano Bensi, Paolo Ruggiero, Simona Tavarini
Publikováno v:
Scientific Reports
Staphylococcus aureus is the major cause of human septic arthritis and osteomyelitis, which deserve special attention due to their rapid evolution and resistance to treatment. The progression of the disease depends on both bacterial presence in situ
Autor:
Birgitta Henriques-Normark, Jeanette Tångrot, Jessica Dagerhamn, Andreas Sandgren, Björn Andersson, Ilias Galanis, Karin Sjöström, Sarah Browall, Tiziana Spadafina, Oscar Franzén, Anuj Pathak, Martin Norman, Åke Örtqvist, Christel Hellberg, Staffan Normark, Patrick Bättig
Publikováno v:
The Journal of Infectious Diseases. 209:377-388
Background. Pneumococcal serotypes are represented by a varying number of clonal lineages with different genetic contents, potentially affecting invasiveness. However, genetic variation within the same genetic lineage may be larger than anticipated.
Autor:
Anna Rita Taddei, Davide Serruto, Mariagrazia Pizza, Beatrice Aricò, Rino Rappuoli, Marco R. Oggioni, Sonja Höhle, Stefania Bambini, Esteban Veiga, Maria Scarselli, Tiziana Spadafina, Ilaria Ferlenghi, Vega Masignani, Pascale Cossart, Mogens Kilian, Silvana Savino, Maurizio Comanducci
Publikováno v:
Serruto, D, Spadafina, T, Scarselli, M, Bambini, S, Comanducci, M, Höhle, S, Kilian, M, Veiga, E, Cossart, P, Oggioni, M R, Savino, S, Ferlenghi, I, Taddei, A R, Rappuoli, R, Pizza, M, Masignani, V & Aricò, B 2009, ' HadA is an atypical new multifunctional trimeric coiled-coil adhesin of Haemophilus influenzae biogroup aegyptius, which promotes entry into host cells ', Cellular Microbiology, vol. 11, pp. 1044-1063 . https://doi.org/10.1111/j.1462-5822.2009.01306.x
Summary The Oca (Oligomeric coiled-coil adhesin) family is a subgroup of the bacterial trimeric autotrans- porter adhesins, which includes structurally related proteins, such as YadA of Yersinia entero- colitica and NadA of Neisseria meningitidis. In
Autor:
Sofia Ygberg-Eriksson, Martin Norman, Sofia Orrskog, Staffan Normark, Marilena Gallotta, Carl G. Gahmberg, Michèle A. Barocchi, Björn Johansson, Karina Hentrich, Liisa M. Uotila, Birgitta Henriques-Normark, Matthias Gunzer, Stefan Fälker, Samuli Rounioja, Mike Hasenberg, Tiziana Spadafina
Publikováno v:
Scopus-Elsevier
mBio, Vol 4, Iss 1 (2013)
mBio
mBio, Vol 4, Iss 1 (2013)
mBio
Pneumococcal pili have been shown to influence pneumococcal colonization, disease development, and the inflammatory response in mice. The role of the pilus-associated RrgA adhesin in pneumococcal interactions with murine and human macrophages was inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b061de9ab23c5a05ac276c7ac6ee81
http://hdl.handle.net/10138/166984
http://hdl.handle.net/10138/166984
Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans
Autor:
Lisa A. Lewis, Andrew G. Plaut, J. Simon Kroll, Maria Scarselli, Clíona A. O'Dwyer, Tiziana Spadafina, John J. Donnelly, Mariagrazia Pizza, Alessia Biolchi, Paolo Costantino, Rino Rappuoli, Laura Santini, Laura Ciucchi, Beatrice Aricò, Marta Tontini, Francesco Berti, Silvana Savino, Jiazhou Qiu, Sanjay Ram, Davide Serruto, Marzia Monica Giuliani, Kate L. Seib, Richard Moxon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(8)
GNA2132 is a Neisseria meningitidis antigen of unknown function, discovered by reverse vaccinology, which has been shown to induce bactericidal antibodies in animal models. Here we show that this antigen induces protective immunity in humans and it i