Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Tiziana Pascucci"'
Autor:
Dario Esposito, Gianluca Cruciani, Laura Zaccaro, Emanuele Di Carlo, Grazia Fernanda Spitoni, Filippo Manti, Claudia Carducci, Elena Fiori, Vincenzo Leuzzi, Tiziana Pascucci
Publikováno v:
Brain Sciences, Vol 14, Iss 5, p 481 (2024)
Hyperserotonemia is one of the most studied endophenotypes in autism spectrum disorder (ASD), but there are still no unequivocal results about its causes or biological and behavioral outcomes. This systematic review summarizes the studies investigati
Externí odkaz:
https://doaj.org/article/daeed5283e24473a830ae2baca0c72f1
Autor:
Alessandro Bregalda, Claudia Carducci, Maria Teresa Viscomi, Francesca Pierigè, Sara Biagiotti, Michele Menotta, Federica Biancucci, Tiziana Pascucci, Vincenzo Leuzzi, Mauro Magnani, Luigia Rossi
Publikováno v:
Neurobiology of Disease, Vol 180, Iss , Pp 106093- (2023)
Untreated phenylketonuria (PKU) patients and PKU animal models show hypomyelination in the central nervous system and white matter damages, which are accompanied by myelin basic protein (MBP) impairment. Despite many assumptions, the primary explanat
Externí odkaz:
https://doaj.org/article/ea2f98d722914820afd10ddc5e353fa0
Autor:
Marzia Bianchi, Luigia Rossi, Francesca Pierigè, Pietro De Angeli, Mattia Paolo Aliano, Claudia Carducci, Emanuele Di Carlo, Tiziana Pascucci, Francesca Nardecchia, Vincenzo Leuzzi, Mauro Magnani
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 26-40 (2022)
Here we report, for the first time, the engineering of human red blood cells (RBCs) with an entire metabolic pathway as a potential strategy to treat patients with guanidinoacetate methyltransferase (GAMT) deficiency, capable of reducing the high tox
Externí odkaz:
https://doaj.org/article/072330cee6434a5fa288ce93803cac8c
Autor:
Micaela Di Consiglio, Sheila Merola, Chiara Satta, Tiziana Pascucci, Cristiano Violani, Alessandro Couyoumdjian
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
University students’ mental health has become a public health issue since increasingly students report high levels of psychological distress. Mental health difficulties influence students’ lives, such as academic performance, relationships satisf
Externí odkaz:
https://doaj.org/article/82c75c2da99b4879a1fffa614db99da0
Autor:
Luisa Lo Iacono, Camilla Mancini, Lucy Babicola, Marco Pietrosanto, Matteo Di Segni, Sebastian Luca D'Addario, Diana Municchi, Donald Ielpo, Tiziana Pascucci, Simona Cabib, Fabio Ferlazzo, Francesca R. D'Amato, Diego Andolina, Manuela Helmer-Citterich, Carlo Cifani, Rossella Ventura
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100406- (2021)
Early life experiences that affect the attachment bond formation can alter developmental trajectories and result in pathological outcomes in a sex-related manner. However, the molecular basis of sex differences is quite unknown. The dopaminergic syst
Externí odkaz:
https://doaj.org/article/55d0c1a428dd4d86a0a923946663c45b
Autor:
Tiziana Pascucci, Marco Colamartino, Elena Fiori, Roberto Sacco, Annalisa Coviello, Rossella Ventura, Stefano Puglisi-Allegra, Laura Turriziani, Antonio M. Persico
Publikováno v:
Brain Sciences, Vol 10, Iss 4, p 233 (2020)
Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction/communication, stereotypic behaviors, restricted interests, and abnormal sensory-processing. Several studies have reported sig
Externí odkaz:
https://doaj.org/article/3e27b6efe7314fdea31113feb96dff6a
Autor:
Francesca Nardecchia, Rosamaria Orlando, Luisa Iacovelli, Marco Colamartino, Elena Fiori, Vincenzo Leuzzi, Sonia Piccinin, Robert Nistico, Stefano Puglisi-Allegra, Luisa Di Menna, Giuseppe Battaglia, Ferdinando Nicoletti, Tiziana Pascucci
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
We studied group-I metabotropic glutamate (mGlu) receptors in Pahenu2 (ENU2) mice, which mimic the genetics and neurobiology of human phenylketonuria (PKU), a metabolic disorder characterized, if untreated, by autism, and intellectual disability (ID)
Externí odkaz:
https://doaj.org/article/5901536695d54d86a5d0f31543b2b298
Autor:
Elena Fiori, Diego Oddi, Rossella Ventura, Marco Colamartino, Alessandro Valzania, Francesca Romana D'Amato, Vibeke Bruinenberg, Eddy van der Zee, Stefano Puglisi-Allegra, Tiziana Pascucci
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183430 (2017)
Phenylketonuria (PKU) is one of the most common human inborn errors of metabolism, caused by phenylalanine hydroxylase deficiency, leading to high phenylalanine and low tyrosine levels in blood and brain causing profound cognitive disability, if untr
Externí odkaz:
https://doaj.org/article/9092d6542d454a30bd2dc3601df17bb2
Autor:
Tiziana Pascucci, Giacomo Giacovazzo, Diego Andolina, Alessandra Accoto, Elena Fiori, Rossella Ventura, Cristina Orsini, David Conversi, Claudia Carducci, Vincenzo Leuzzi, Stefano Puglisi-Allegra
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84697 (2013)
Hyperphenylalaninemia (HPA) refers to all clinical conditions characterized by increased amounts of phenylalanine (PHE) in blood and other tissues. According to their blood PHE concentrations under a free diet, hyperphenylalaninemic patients are comm
Externí odkaz:
https://doaj.org/article/196aa9ef15e14892ba96011e366856e9
Autor:
Francesca R D'Amato, Claudio Zanettini, Valentina Lampis, Roberto Coccurello, Tiziana Pascucci, Rossella Ventura, Stefano Puglisi-Allegra, Chiara A M Spatola, Paola Pesenti-Gritti, Diego Oddi, Anna Moles, Marco Battaglia
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18637 (2011)
In man, many different events implying childhood separation from caregivers/unstable parental environment are associated with heightened risk for panic disorder in adulthood. Twin data show that the occurrence of such events in childhood contributes
Externí odkaz:
https://doaj.org/article/06a5674e647341f48560abef6b1d9155