Loss of the extracellular matrix glycoprotein EMILIN1 accelerates Δ16HER2-driven breast cancer initiation in mice

Autor: Andrea Favero, Ilenia Segatto, Alessandra Capuano, Maria Chiara Mattevi, Gian Luca Rampioni Vinciguerra, Lorena Musco, Sara D’Andrea, Alessandra Dall’Acqua, Chiara Gava, Tiziana Perin, Samuele Massarut, Cristina Marchini, Gustavo Baldassarre, Paola Spessotto, Barbara Belletti

Publikováno v: npj Breast Cancer, Vol 10, Iss 1, Pp 1-13 (2024)

Abstract The extracellular matrix (ECM) is an important component of the tumor microenvironment and undergoes extensive remodeling during both initiation and progression of breast cancer (BC). EMILIN1 is an ECM glycoprotein, whose function has been l

Externí odkaz: https://doaj.org/article/94c039bc73e742b7b2fce23bcd66a259

Clinical validation of full HR-HPV genotyping HPV Selfy assay according to the international guidelines for HPV test requirements for cervical cancer screening on clinician-collected and self-collected samples

Autor: Alice Avian, Nicolò Clemente, Elisabetta Mauro, Erica Isidoro, Michela Di Napoli, Sandra Dudine, Anna Del Fabro, Stefano Morini, Tiziana Perin, Fabiola Giudici, Tamara Cammisuli, Nicola Foschi, Marco Mocenigo, Michele Montrone, Chiara Modena, Martina Polenghi, Luca Puzzi, Vjekoslav Tomaic, Giulio Valenti, Riccardo Sola, Shivani Zanolla, Enea Vogrig, Elisabetta Riva, Silvia Angeletti, Massimo Ciccozzi, Santina Castriciano, Maria Pachetti, Matteo Petti, Sandro Centonze, Daniela Gerin, Lawrence Banks, Bruna Marini, Vincenzo Canzonieri, Francesco Sopracordevole, Fabrizio Zanconati, Rudy Ippodrino

Publikováno v: Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-12 (2022)

Abstract Background According to international guidelines, Human Papillomavirus (HPV) DNA tests represent a valid alternative to Pap Test for primary cervical cancer screening, provided that they guarantee balanced clinical sensitivity and specificit

Externí odkaz: https://doaj.org/article/b3f76b8b76204f669082533c149742bd

Machine learning using the extreme gradient boosting (XGBoost) algorithm predicts 5-day delta of SOFA score at ICU admission in COVID-19 patients

Autor: Jonathan Montomoli, Luca Romeo, Sara Moccia, Michele Bernardini, Lucia Migliorelli, Daniele Berardini, Abele Donati, Andrea Carsetti, Maria Grazia Bocci, Pedro David Wendel Garcia, Thierry Fumeaux, Philippe Guerci, Reto Andreas Schüpbach, Can Ince, Emanuele Frontoni, Matthias Peter Hilty, Mario Alfaro-Farias, MD, Gerardo Vizmanos-Lamotte, MD, PhD, Thomas Tschoellitsch, MD, Jens Meier, MD, Hernán Aguirre-Bermeo, MD, PhD, Janina Apolo, BSc, Alberto Martínez, MD, Geoffrey Jurkolow, MD, Gauthier Delahaye, MD, Emmanuel Novy, MD, Marie-Reine Losser, MD, PhD, Tobias Wengenmayer, MD, Jonathan Rilinger, MD, Dawid L. Staudacher, MD, Sascha David, MD, Tobias Welte, MD, Klaus Stahl, MD, “Agios Pavlos”, Theodoros Aslanidis, MD, PhD, Anita Korsos, MD, Barna Babik, MD, PhD, Reza Nikandish, MD, Emanuele Rezoagli, MD, PhD, Matteo Giacomini, MD, Alice Nova, MD, Alberto Fogagnolo, MD, Savino Spadaro, MD, PhD, Roberto Ceriani, MD, Martina Murrone, MD, Maddalena A. Wu, MD, Chiara Cogliati, MD, Riccardo Colombo, MD, Emanuele Catena, MD, Fabrizio Turrini, MD, MSc, Maria Sole Simonini, MD, Silvia Fabbri, MD, Antonella Potalivo, MD, Francesca Facondini, MD, Gianfilippo Gangitano, MD, Tiziana Perin, MD, Maria Grazia Bocci, MD, Massimo Antonelli, MD, Diederik Gommers, MD, PhD, Raquel Rodríguez-García, MD, Jorge Gámez-Zapata, MD, Xiana Taboada-Fraga, MD, Pedro Castro, MD, Adrian Tellez, MD, Arantxa Lander-Azcona, MD, Jesús Escós-Orta, MD, Maria C. Martín-Delgado, MD, Angela Algaba-Calderon, MD, Diego Franch-Llasat, MD, Ferran Roche-Campo, MD, PhD, Herminia Lozano-Gómez, MD, Begoña Zalba-Etayo, MD, PhD, Marc P. Michot, MD, Alexander Klarer, Rolf Ensner, MD, Peter Schott, MD, Severin Urech, MD, Nuria Zellweger, Lukas Merki, MD, Adriana Lambert, MD, Marcus Laube, MD, Marie M. Jeitziner, RN, PhD, Beatrice Jenni-Moser, RN, MSc, Jan Wiegand, MD, Bernd Yuen, MD, Barbara Lienhardt-Nobbe, Andrea Westphalen, MD, Petra Salomon, MD, Iris Drvaric, MD, Frank Hillgaertner, MD, Marianne Sieber, Alexander Dullenkopf, MD, Lina Petersen, MD, Ivan Chau, MD, Hatem Ksouri, MD, PhD, Govind Oliver Sridharan, MD, Sara Cereghetti, MD, Filippo Boroli, MD, Jerome Pugin, MD, PhD, Serge Grazioli, MD, Peter C. Rimensberger, MD, Christian Bürkle, MD, Julien Marrel, MD, Mirko Brenni, MD, Isabelle Fleisch, MD, Jerome Lavanchy, MD, Marie-Helene Perez, MD, Anne-Sylvie Ramelet, MD, Anja Baltussen Weber, MD, Peter Gerecke, MD, Andreas Christ, MD, Samuele Ceruti, MD, Andrea Glotta, MD, Katharina Marquardt, MD, Karim Shaikh, MD, Tobias Hübner, MD, Thomas Neff, MD, Hermann Redecker, MD, Mallory Moret-Bochatay, MD, FriederikeMeyer zu Bentrup, MD, MBA, Michael Studhalter, MD, Michael Stephan, MD, Jan Brem, MD, Nadine Gehring, MD, Daniela Selz, MD, Didier Naon, MD, Gian-Reto Kleger, MD, Urs Pietsch, MD, Miodrag Filipovic, MD, Anette Ristic, MD, Michael Sepulcri, MD, Antje Heise, MD, Marilene Franchitti Laurent, MD, Jean-Christophe Laurent, MD, Pedro D. Wendel Garcia, MSc, Reto Schuepbach, MD, Dorothea Heuberger, PhD, Philipp Bühler, MD, Silvio Brugger, MD, PhD, Patricia Fodor, MD, Pascal Locher, MD, Giovanni Camen, MD, Tomislav Gaspert, MD, Marija Jovic, MD, Christoph Haberthuer, MD, Roger F. Lussman, MD, Elif Colak, MD

Publikováno v: Journal of Intensive Medicine, Vol 1, Iss 2, Pp 110-116 (2021)

Background: Accurate risk stratification of critically ill patients with coronavirus disease 2019 (COVID-19) is essential for optimizing resource allocation, delivering targeted interventions, and maximizing patient survival probability. Machine lear

Externí odkaz: https://doaj.org/article/7e7afa9d7e874b589c9f3eb1b5df67cb

Lung ultrasound monitoring of CPAP effectiveness on SARS-CoV-2 pneumonia: A case report

Autor: Marco Montanari, Pierpaolo De Ciantis, Andrea Boccatonda, Marta Venturi, Giuseppe d'Antuono, Gianfilippo Gangitano, Giulio Cocco, Damiano D'Ardes, Cosima Schiavone, Fabrizio Giostra, Tiziana Perin

Publikováno v: Emergency Care Journal, Vol 16, Iss 3 (2020)

SARS-CoV-2 infection is characterized by extremely heterogeneous features, going from cases with few symptoms to severe respiratory failures. Chest Computed Tomography (CT) is currently the gold-standard imaging method, although burdened by the risk

Externí odkaz: https://doaj.org/article/c6b55716516a4309bd0dd7e7fe503bb5

Extramammary Paget disease of the vulva: immunohistochemical analysis of neoangiogenesis and epithelial-mesenchymal transition markers expression

Autor: Lara Alessandrini, Nicolò Clemente, Tiziana Perin, Giorgio Giorda, Vincenzo Canzonieri, Francesco Sopracordevole

Publikováno v: Diagnostic Pathology, Vol 13, Iss 1, Pp 1-8 (2018)

Abstract Background Extra-mammary Paget’s disease of the vulva (EMPDV) is an infrequent chronic disease that often recurs. The aim of the study was to assess the presence of neoangiogenesis and the expression of epithelial-mesenchymal transition (E

Externí odkaz: https://doaj.org/article/30d80a0994e847c7b32d16df78303855