Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Tiziana, Ottone"'
Autor:
Francesca Liccardo, Martyna Śniegocka, Claudia Tito, Alessia Iaiza, Tiziana Ottone, Mariadomenica Divona, Serena Travaglini, Maurizio Mattei, Rosella Cicconi, Selenia Miglietta, Giuseppe Familiari, Stefania Annarita Nottola, Vincenzo Petrozza, Luca Tamagnone, Maria Teresa Voso, Silvia Masciarelli, Francesco Fazi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-15 (2023)
Abstract Background Acute myeloid leukemia (AML) patients bearing the ITD mutation in the tyrosine kinase receptor FLT3 (FLT3-ITD) present a poor prognosis and a high risk of relapse. FLT3-ITD is retained in the endoplasmic reticulum (ER) and generat
Externí odkaz:
https://doaj.org/article/ce760a3147f546ac978dda45ec44dbda
Autor:
Giorgia Silvestrini, Tiziana Ottone, Rocco Giovanni Piazza, Serena Travaglini, Carmelo Gurnari, Francesco Marchesi, Anna Maria Nardozza, Emiliano Fabiani, Enrico Attardi, Mariadomenica Divona, Paola Ricci, Maria Antonietta Irno Consalvo, Sara Ienzi, Roberto Arcese, Annalisa Biagi, Luciano Fiori, Mariangela Novello, Alessandro Mauriello, Adriano Venditti, Lucia Anemona, Maria Teresa Voso
Publikováno v:
HemaSphere, Vol 7, p e9215641 (2023)
Externí odkaz:
https://doaj.org/article/14c13fc8705943cfbc151cd0ca6ed9e6
Autor:
Enrico Attardi, Arianna Savi, Beatrice Borsellino, Alfonso Piciocchi, Marta Cipriani, Tiziana Ottone, Emiliano Fabiani, Mariadomenica Divona, Serena Travaglini, Maria Rosaria Pascale, Arda Durmaz, Valeria Visconte, Matteo Giovanni Della Porta, Adriano Venditti, Jaroslaw P Maciejewski, Carmelo Gurnari, Maria Teresa Voso
Publikováno v:
HemaSphere, Vol 7, p e5402602 (2023)
Externí odkaz:
https://doaj.org/article/663c2cc6678c48ea8de850efcc49e394
Autor:
Gabriele Lo Iudice, Eleonora De Bellis, Arianna Savi, Luca Guarnera, Alice Massacci, Francesca De Nicola, Frauke Goeman, Tiziana Ottone, Mariadomenica Divona, Matteo Pallocca, Maurizio Fanciulli, Maria Teresa Voso, Gennaro Ciliberto
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-6 (2022)
Abstract Acute Myeloid Leukaemia (AML) is a haematological malignancy showing a hypervariable landscape of clinical outcomes and phenotypic differences, explainable by heterogeneity at the cellular and molecular level. Among the most common genomic a
Externí odkaz:
https://doaj.org/article/24f573e564454ba498dab8ec0e97e9d6
Autor:
Zaira Ianniello, Melissa Sorci, Lavinia Ceci Ginistrelli, Alessia Iaiza, Marcella Marchioni, Claudia Tito, Ernestina Capuano, Silvia Masciarelli, Tiziana Ottone, Cristina Attrotto, Manuela Rizzo, Luca Franceschini, Stefano de Pretis, Maria Teresa Voso, Mattia Pelizzola, Francesco Fazi, Alessandro Fatica
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Abstract Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by the presence of tyrosine kinase BCR-ABL1 fusion protein, which deregulate transcription and mRNA translation. Tyrosine kinase inhibitors (TKIs) are the first-choice tr
Externí odkaz:
https://doaj.org/article/0405da38b446423ba4b125b9e7a9c8a5
Autor:
Emiliano Fabiani, Laura Cicconi, Anna Maria Nardozza, Antonio Cristiano, Marianna Rossi, Tiziana Ottone, Giulia Falconi, Mariadomenica Divona, Anna Maria Testi, Ombretta Annibali, Roberto Castelli, Vladimir Lazarevic, Eduardo Rego, Pau Montesinos, Jordi Esteve, Adriano Venditti, Matteo Della Porta, William Arcese, Francesco Lo‐Coco, Maria Teresa Voso
Publikováno v:
Cancer Medicine, Vol 10, Iss 12, Pp 3839-3847 (2021)
Abstract Background The ZBTB16‐RARA fusion gene, resulting from the reciprocal translocation between ZBTB16 on chromosome 11 and RARA genes on chromosome 17 [t(11;17)(q23;q21)], is rarely observed in acute myeloid leukemia (AML), and accounts for a
Externí odkaz:
https://doaj.org/article/65f7159aca3f488c9a7bad0da0d53eea
Autor:
Tiziana Ottone, Isabella Faraoni, Giorgio Fucci, Mariadomenica Divona, Serena Travaglini, Eleonora De Bellis, Francesco Marchesi, Daniela Francesca Angelini, Raffaele Palmieri, Carmelo Gurnari, Manuela Giansanti, Anna Maria Nardozza, Federica Montesano, Emiliano Fabiani, Elisa Linnea Lindfors Rossi, Raffaella Cerretti, Laura Cicconi, Marco De Bardi, Maria Luisa Catanoso, Luca Battistini, Renato Massoud, Adriano Venditti, Maria Teresa Voso
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Vitamin C has been shown to play a significant role in suppressing progression of leukemia through epigenetic mechanisms. We aimed to study the role of vitamin C in acute myeloid leukemia (AML) biology and clinical course. To this purpose, the plasma
Externí odkaz:
https://doaj.org/article/3addc2e8b97f4c029ccc1a66b6cbd388
Autor:
Beatrice Borsellino, Arianna Savi, Maria Rosaria Pascale, Elisa Meddi, Antonio Cristiano, TIZIANA OTTONE, Maria Cristina Rapanotti, Mariadomenica Divona, SERENA TRAVAGLINI, Enrico Attardi, Elisa Buzzatti, Francesco Buccisano, Maria Teresa Voso
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 14, Iss 1 (2022)
Evolution of myeloproliferative neoplasms (MPN) to acute myeloid leukemia (AML) occurs in 2-10% of patients, whereas the reverse path from AML to MPN has been rarely reported. We herein present a 75-year-old woman with AML, in whom a JAK2-V617F po
Externí odkaz:
https://doaj.org/article/7a7d0f8680b4420fb3fa57fb24b6a186
Autor:
Antonio Cristiano, Raffaele Palmieri, Emiliano Fabiani, Tiziana Ottone, Mariadomenica Divona, Arianna Savi, Francesco Buccisano, Luca Maurillo, Corrado Tarella, William Arcese, Maria Teresa Voso
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 14, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/5d7661ee23d74c37974762e63adf7133
Autor:
Luca Guarnera, Tiziana Ottone, Emiliano Fabiani, Mariadomenica Divona, Arianna Savi, Serena Travaglini, Giulia Falconi, Paola Panetta, Maria Cristina Rapanotti, Maria Teresa Voso
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Acute promyelocytic leukemia (APL) accounts for 10–15% of newly diagnosed acute myeloid leukemias (AML) and is typically caused by the fusion of promyelocytic leukemia with retinoic acid receptor α (RARA) gene. The prognosis is excellent, thanks t
Externí odkaz:
https://doaj.org/article/b120b3adb1fd47f6a671e5df02f96124