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Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism

Autor: Hasel, Philip, Dando, Owen, Jiwaji, Zoeb, Baxter, Paul, Todd, Alison C., Heron, Samuel, Márkus, Nóra M., Mcqueen, Jamie, Hampton, David W., Torvell, Megan, Tiwari, Sachin S., Mckay, Sean, Eraso-pichot, Abel, Zorzano, Antonio, Masgrau, Roser, Galea, Elena, Chandran, Siddharthan, Wyllie, David J. A., Simpson, T. Ian, Hardingham, Giles E.

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Hasel, P, Dando, O, Jiwaji, Z, Baxter, P, Todd, A C, Heron, S, Márkus, N M, Mcqueen, J, Hampton, D W, Torvell, M, Tiwari, S S, Mckay, S, Eraso-pichot, A, Zorzano, A, Masgrau, R, Galea, E, Chandran, S, Wyllie, D J A, Simpson, T I & Hardingham, G E 2017, ' Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism ', Nature Communications, vol. 8, 15132, pp. 1-17 . https://doi.org/10.1038/ncomms15132

The influence that neurons exert on astrocytic function is poorly understood. To investigate this, we first developed a system combining cortical neurons and astrocytes from closely related species, followed by RNA-seq and in silico species separatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::48fa24451ec7b8e7b6cde7b7349ee372
https://doaj.org/article/f17cb8505a5e4abe82484929859194ff

Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer's disease.

Autor: Tiwari, Sachin S.¹, d'Orange, Marie¹, Troakes, Claire², Shurovi, Badrun N.¹, Engmann, Olivia¹, Noble, Wendy³, Hortobágyi, Tibor^2,4, Giese, Karl P.^1,5 Karl.Giese@kcl.ac.uk

Publikováno v: Molecular Brain. 2015, Vol. 8 Issue 1, p1-12. 12p.

Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer's disease

Autor: Tiwari, Sachin S, d’Orange, Marie, Troakes, Claire, Shurovi, Badrun N, Engmann, Olivia, Noble, Wendy, Hortobágyi, Tibor, Giese, Karl P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f630eccdfd20bb29f96781a3c892fcef

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