Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Tityustoxin"'
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 37, Iss 3, Pp 385-390 (2004)
The pharmacokinetics of scorpion venom and its toxins has been investigated in experimental models using adult animals, although, severe scorpion accidents are associated more frequently with children. We compared the effect of age on the pharmacokin
Externí odkaz:
https://doaj.org/article/8ff92497adcd4dca874a1643afbd6d48
Autor:
Maria Elena de Lima, Robson A.S. Santos, Cibele Rocha-Resende, Thiago Verano-Braga, Nádia Miricéia Leão, Adriano Monteiro de Castro Pimenta
Publikováno v:
Peptides. 98:70-77
Cryptome is as a subset of a given proteome containing bioactive cryptides embedded in larger peptides or proteins. We pinpointed a striking sequence similarity between two peptides from the Tityus serrulatus venom: Ts10 (KKDGYPVEYDRAY) and the N-ter
Autor:
Natalia L. S. Machado, R.C. de Menezes, Deoclécio A. Chianca, Patrícia Alves Maia Guidine, Tasso Moraes-Santos, Fernanda Cacilda dos Santos Silva, Carlos Henrique Xavier, Márcio Flávio Moraes
Publikováno v:
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
The scorpion envenoming syndrome is an important worldwide public health problem due to its high incidence and potential severity of symptoms. Some studies address the high sensitivity of the central nervous system to this toxin action. It is known t
Autor:
Ricardo Nascimento Araújo, Patrícia Alves Maia Guidine, Rosa Maria Esteves Arantes, Iva Tereza Van Fraga, Tasso Moraes-Santos, André R. Massensini, Marcelo Limborço-Filho, Juliana Carvalho-Tavares, Márcio Flávio Dutra Moraes, Onésia Cristina Oliveira Lima, Norinne Lacerda-Queiroz
Publikováno v:
Neuroscience Letters. 588:24-28
Accidents caused by scorpion stings, mainly affecting children, are considered an important cause of morbidity and mortality in tropical countries. Clinical studies demonstrate the relevant role of systemic inflammatory events in scorpion envenoming.
Akademický článek
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Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Neural Plasticity
Neural Plasticity
In the last years it has been increasingly clear thatKV-channel activity modulates neurotransmitter release. The subcellular localization and composition of potassium channels are crucial to understanding its influence on neurotransmitter release. To
Publikováno v:
Protein Science. 11:390-400
Ion channels are involved in diverse biological processes and play essential roles in the physiology of all cells. An increasing number of human and animal diseases have been identified as relating to the defective function of ion channels. Scorpion
Autor:
Michel Mesquita, Patrícia Alves Maia Guidine, André R. Massensini, Tasso Moraes-Santos, Márcio Flávio Dutra Moraes
Publikováno v:
NeuroToxicology. 30:90-96
Scorpion envenomation is a public health problem in Brazil, with most severe cases occuring in children under the age of 5 years (0.6% lethality). In fact, the toxic fractions of the Tityus serrulatus scorpion venom (TSSV) have greater permeability a
Autor:
Márcio Flávio Dutra Moraes, André R. Massensini, Patrícia Alves Maia Guidine, Tasso Moraes-Santos
Publikováno v:
Brain Research. 1239:256-260
The scorpion-envenoming syndrome has an incidence of approximately 8000 accidents/year in Brazil; with most severe cases occurring during childhood and elderly. Previous results from our laboratory suggest that the effects of scorpion toxins on the c
Autor:
Wangcai Gao, Kenneth C. Reinert, Gang Chen, Claudia M. Hendrix, Timothy J. Ebner, Laurentiu S. Popa, M. Elizabeth Ross
Publikováno v:
Journal of Neurophysiology. 94:1287-1298
Spreading acidification and depression (SAD) is a form of propagated activity in the cerebellar cortex characterized by acidification and a transient depression in excitability. This study investigated the role of Kv1 potassium channels in SAD using