Výsledky vyhledávání - "Titus K Kwambai"

Akademický článek

Policy uptake and implementation of the RTS,S/AS01 malaria vaccine in sub-Saharan African countries: status 2 years following the WHO recommendation

Autor: Feiko O ter Kuile, Simon Kariuki, Jenny Hill, Eleanor Ochodo, Caleb Kimutai Sagam, Caroline Bonareri Osoro, Titus K Kwambai, Jenifer Akoth Otieno, Lisa Were, Eddy Johnson Owino

Publikováno v: BMJ Global Health, Vol 9, Iss 4 (2024)

In October 2021, the WHO recommended the world’s first malaria vaccine—RTS,S/AS01—to prevent malaria in children living in areas with moderate-to-high transmission in sub-Saharan Africa (SSA). A second malaria vaccine, R21/Matrix-M, was recomme

Externí odkaz: https://doaj.org/article/62d3319011fe4d888e36fd39d2a00d3f

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Akademický článek

Post-discharge malaria chemoprevention in children admitted with severe anaemia in malaria-endemic settings in Africa: a systematic review and individual patient data meta-analysis of randomised controlled trials

Autor: Kamija S Phiri, ProfMD PhD, Carole Khairallah, MSc, Titus K Kwambai, MD PhD, Kalifa Bojang, MD PhD, Aggrey Dhabangi, MD PhD, Robert Opoka, MD PhD, Richard Idro, MD PhD, Kasia Stepniewska, PhD, Michael Boele van Hensbroek, ProfPhD, Chandy C John, ProfPhD, Bjarne Robberstad, ProfPhD, Brian Greenwood, ProfMD, Feiko O ter Kuile, ProfMD PhD

Publikováno v: The Lancet Global Health, Vol 12, Iss 1, Pp e33-e44 (2024)

Summary: Background: Severe anaemia is associated with high in-hospital mortality among young children. In malaria-endemic areas, surviving children also have an increased risk of mortality or readmission after hospital discharge. We conducted a syst

Externí odkaz: https://doaj.org/article/39c3c2661e774079a10a953b77bd73e5

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Akademický článek

Malaria chemoprevention with monthly dihydroartemisinin-piperaquine for the post-discharge management of severe anaemia in children aged less than 5 years in Uganda and Kenya: study protocol for a multi-centre, two-arm, randomised, placebo-controlled, superiority trial

Autor: Titus K. Kwambai, Aggrey Dhabangi, Richard Idro, Robert Opoka, Simon Kariuki, Aaron M. Samuels, Meghna Desai, Michael Boele van Hensbroek, Chandy C. John, Bjarne Robberstad, Duolao Wang, Kamija Phiri, Feiko O. ter Kuile

Publikováno v: Trials, Vol 19, Iss 1, Pp 1-12 (2018)

Abstract Background Children hospitalised with severe anaemia in malaria endemic areas in Africa are at high risk of readmission or death within 6 months post-discharge. Currently, no strategy specifically addresses this period. In Malawi, 3 months o

Externí odkaz: https://doaj.org/article/c76ee9c3abe14e80815ee16338ffec5e

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Economic evaluation of postdischarge malaria chemoprevention in preschool children treated for severe anaemia in Malawi, Kenya, and Uganda: A cost-effectiveness analysis

Autor: Melf-Jakob Kühl, Thandile Gondwe, Aggrey Dhabangi, Titus K. Kwambai, Amani T. Mori, Robert Opoka, C. Chandy John, Richard Idro, Feiko O. ter Kuile, Kamija S. Phiri, Bjarne Robberstad

Publikováno v: EClinicalMedicine

Background Children hospitalised with severe anaemia in malaria-endemic areas are at a high risk of dying or being readmitted within six months of discharge. A trial in Kenya and Uganda showed that three months of postdischarge malaria chemopreventio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce92d2985da1ec8dfb8150a155c0e835
https://pubmed.ncbi.nlm.nih.gov/36313146

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Post-discharge morbidity and mortality in children admitted with severe anaemia and other health conditions in malaria-endemic settings in Africa: a systematic review and meta-analysis

Autor: Titus K Kwambai, Amani T Mori, Sarah Nevitt, Anna Maria van Eijk, Aaron M Samuels, Bjarne Robberstad, Kamija S Phiri, Feiko O ter Kuile

BACKGROUND\ud \ud Severe anaemia is associated with high in-hospital mortality among young children. In malaria-endemic areas, surviving children also remain at increased risk of mortality for several months after hospital discharge. We aimed to comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33d80f96b77e1abb5f971bbb322fe9d

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Efficacy of Single-Dose Primaquine With Artemisinin Combination Therapy on Plasmodium falciparum Gametocytes and Transmission: An Individual Patient Meta-Analysis

Publikováno v: The Journal of infectious diseases. Oxford University Press
Journal of infectious diseases, 225(7), 1215-1226. Oxford University Press
The Journal of Infectious Diseases, 225, 1215-1226
The Journal of Infectious Diseases, 225, 7, pp. 1215-1226

Background Since the World Health Organization recommended single low-dose (0.25 mg/kg) primaquine (PQ) in combination with artemisinin-based combination therapies (ACTs) in areas of low transmission or artemisinin-resistant Plasmodium falciparum, se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2d659354a7dc60e75b4f80261d44e6
https://doi.org/10.1093/infdis/jiaa498

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Diagnostic Performance of Loop-Mediated Isothermal Amplification and Ultrasensitive Rapid Diagnostic Tests for Malaria Screening Among Pregnant Women in Kenya

Autor: Aaron M Samuels, Oliver Towett, Brian Seda, Ryan E Wiegand, Kephas Otieno, Miriam Chomba, Naomi Lucchi, Dragan Ljolje, Kammerle Schneider, Patrick G T Walker, Titus K Kwambai, Laurence Slutsker, Feiko O ter Kuile, Simon K Kariuki

Publikováno v: The Journal of infectious diseases. 226(4)

Background Screen-and-treat strategies with sensitive diagnostic tests may reduce malaria-associated adverse pregnancy outcomes. We conducted a diagnostic accuracy study to evaluate new point-of-care tests to screen pregnant women for malaria at thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fdb8c265118e2fe10fbccd5258f5060
https://pubmed.ncbi.nlm.nih.gov/35811308

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