P325: APPLICATIONS OF HIGH-THROUGHPUT DRUG SCREENING AS DRUG REPURPOSING STRATEGY FOR POOR OUTCOME SUBGROUPS OF PEDIATRIC B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA

Autor: Athanasios Oikonomou, Luigia Valsecchi, Manuel Quadri, Titus Watrin, Katerina Scharov, Jia-Wey Tu, Sanil Bhatia, Michela Bardini, Grazia Fazio, Arndt Borkhardt, Chiara Palmi, Giovanni Cazzaniga

Publikováno v: HemaSphere, Vol 7, p e76470de (2023)

Externí odkaz: https://doaj.org/article/3dbb592d72934b529e00874360085253

The RNA Binding Protein Musashi-2 (MSI2) Sustains the Growth and the Leukemogenic Potential of MLL-Rearranged Acute Lymphoblastic Leukemia, and It Is Involved in Glucocorticoid Resistance

Autor: Luigia Valsecchi, Simone Naso, Simona Procopio, Mario Mauri, Rocco Piazza, Titus Watrin, Sanil Bhatia, Valentina Pasquale, Elena Sacco, Chiara Palmi, Grazia Fazio, Luca Trentin, Silvia Bresolin, Andrea Biondi, Giovanni Cazzaniga, Michela Bardini

Publikováno v: Blood. 140:8827-8828

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec53d69ff78d7075c7bf510268a9abdf
https://doi.org/10.1182/blood-2022-166313

3081 – LCK DRUG TARGETING IN PAX5 REARRANGED CASES IN POOR RISK CHILDHOOD B-CELL PRECURSORS ACUTE LYMPHOBLASTIC LEUKAEMIA

Autor: Grazia Fazio, Manuel Quadri, Silvia Bresolin, Chiara Palmi, Michela Bardini, Athanasios Oikonomou, Alberto Peloso, Titus Watrin, Jia-Wey Tu, Katerina Scharov, Sanil Bhatia, Arndt Borkhardt, Andrea Biondi, Giovanni Cazzaniga

Publikováno v: Experimental Hematology. 111:S85

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8c1b786c9e12c35ce6bf56e7ac7e387
https://doi.org/10.1016/j.exphem.2022.07.137

Recurrent Germline Variant in RAD21 Predisposes Children to Lymphoblastic Leukemia or Lymphoma.

Autor: Schedel, Anne¹ (AUTHOR) anne.schedel@uniklinikum-dresden.de, Friedrich, Ulrike Anne¹ (AUTHOR) ulrikeanne.friedrich@uniklinikum-dresden.de, Morcos, Mina N. F.² (AUTHOR) mina.morcos@tum.de, Wagener, Rabea³ (AUTHOR) rabea.wagener@med.uni-duesseldorf.de, Mehtonen, Juha⁴ (AUTHOR) juha.mehtonen@uef.fi, Watrin, Titus³ (AUTHOR) titus.watrin@med.uni-duesseldorf.de, Saitta, Claudia⁵ (AUTHOR) c.saitta2@campus.unimib.it, Brozou, Triantafyllia³ (AUTHOR) triantafyllia.brozou@med.uni-duesseldorf.de, Michler, Pia¹ (AUTHOR) pia.michler@uniklinikum-dresden.de, Walter, Carolin⁶ (AUTHOR) carolin.walter@uni-muenster.de, Försti, Asta^7,8 (AUTHOR) a.foersti@kitz-heidelberg.de, Baksi, Arka⁹ (AUTHOR) arka.baksi@tu-dresden.de, Menzel, Maria¹ (AUTHOR) maria.menzel@uniklinikum-dresden.de, Horak, Peter¹⁰ (AUTHOR) peter.horak@nct-heidelberg.de, Paramasivam, Nagarajan¹¹ (AUTHOR) n.paramasivam@dkfz-heidelberg.de, Fazio, Grazia⁵ (AUTHOR) g.fazio@hsgerardo.org, Autry, Robert J^7,8 (AUTHOR) robert.autry@kitz-heidelberg.de, Fröhling, Stefan¹⁰ (AUTHOR) stefan.froehling@nct-heidelberg.de, Suttorp, Meinolf¹ (AUTHOR) meinolf.suttorp@uniklinikum-dresden.de, Gertzen, Christoph¹² (AUTHOR) christoph.gertzen@hhu.de

Publikováno v: International Journal of Molecular Sciences. May2022, Vol. 23 Issue 9, p5174-5174. 15p.

P325: APPLICATIONS OF HIGH-THROUGHPUT DRUG SCREENING AS DRUG REPURPOSING STRATEGY FOR POOR OUTCOME SUBGROUPS OF PEDIATRIC B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA.

Autor: Oikonomou, Athanasios, Valsecchi, Luigia, Quadri, Manuel, Watrin, Titus, Scharov, Katerina, Tu, Jia-Wey, Bhatia, Sanil, Bardini, Michela, Fazio, Grazia, Borkhardt, Arndt, Palmi, Chiara, Cazzaniga, Giovanni

Publikováno v: HemaSphere; 2023 Supplement 3, Vol. 7, pe76470de-e76470de, 1p