Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Titilope A. Ishola"'
Autor:
B. Mark Evers, Titilope A. Ishola, Jingbo Qiao, Junghee Kang, Dai H. Chung, Piotr G. Rychahou
Publikováno v:
Proceedings of the National Academy of Sciences. 105:12891-12896
Neuroblastoma accounts for nearly 15% of all pediatric cancer-related deaths. We have previously shown that gastrin-releasing peptide (GRP) stimulates neuroblastoma growth, and that its cell surface receptor, GRP-R, is overexpressed in advanced-stage
Autor:
Dai H. Chung, Joshua M. Mourot, Titilope A. Ishola, Junghee Kang, B. M. Evers, Piotr G. Rychahou
Publikováno v:
Oncogene. 27:3999-4007
Angiogenesis in neuroblastoma (NB) correlates with increased expression of vascular endothelial growth factor (VEGF) and a worse clinical outcome. Other cellular markers, such as Akt activation and MYCN amplification, are also associated with poor pr
Autor:
B. Mark Evers, Jingbo Qiao, Titilope A. Ishola, Dai H. Chung, Piotr G. Rychahou, Jung Hee Kang
Publikováno v:
Biochemical and Biophysical Research Communications. 351:192-197
MYCN amplification strongly correlates with unfavorable outcomes in patients with neuroblastoma. The aim of this study was to investigate the role of MYCN in neuroblastoma cell differentiation and apoptosis. We used the technique of RNA interference
Publikováno v:
Current pediatric reviews. 5(2)
Neuroblastoma is the third most common pediatric cancer in the United States and is responsible for 15% of pediatric cancer-related deaths. Despite major advances in multimodal therapy, the clinical outcome for several patients remains poor. Due to t
Autor:
Hita Adwanikar, Cara Ramsey, Yu Fu, Jeong Han, Volker Neugebauer, Titilope A. Ishola, Michelle Scerbo
Publikováno v:
Molecular Pain
Molecular Pain, Vol 4, Iss 1, p 26 (2008)
Molecular Pain, Vol 4, Iss 1, p 26 (2008)
The laterocapsular division of the central nucleus of the amygdala (CeLC) has emerged as an important site of pain-related plasticity and pain modulation. Glutamate and neuropeptide receptors in the CeLC contribute to synaptic and behavioral changes
Autor:
Titilope A. Ishola, Dai H. Chung
Publikováno v:
Surgical oncology. 16(3)
Neuroblastomas continue to remain a clinical challenge, despite advances in multimodal therapy. Currently, studies are aimed at novel targets for neuroblastoma directed toward poor prognostic indicators such as the MYCN oncogene and marked angiogenes
Autor:
Piotr G. Rychahou, Joshua M. Mourot, Jung Hee Kang, Dai H. Chung, B. Mark Evers, Titilope A. Ishola, Naira Baregamian
Publikováno v:
Cancer letters. 253(2)
Gastrin-releasing peptide (GRP), the mammalian equivalent of bombesin (BBS), is a trophic factor for highly vascular neuroblastomas; its mechanisms of action in vivo are unknown. We sought to determine the effects of BBS on the growth of neuroblastom
Publikováno v:
Biochimica et biophysica acta. 1770(6)
Gastrin-releasing peptide (GRP), the mammalian equivalent of bombesin (BBS), is an autocrine growth factor for neuroblastoma; its receptor is up-regulated in undifferentiated neuroblastomas. Phosphatidylinositol 3-kinase (PI3K) is a critical cell sur