Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Titilola D. Kalejaiye"'
Autor:
Titilola D. Kalejaiye, Rohan Bhattacharya, Morgan A. Burt, Tatianna Travieso, Arinze E. Okafor, Xingrui Mou, Maria Blasi, Samira Musah
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the Coronavirus disease 2019 (COVID-19), which has resulted in over 5.9 million deaths worldwide. While cells in the respiratory system are the initial target of SARS-CoV-2, there is
Externí odkaz:
https://doaj.org/article/0968fc8e2ad0450e90532e79651e7919
Autor:
Xingrui Mou, Jessica Shah, Rohan Bhattacharya, Titilola D. Kalejaiye, Bowen Sun, Po-Chun Hsu, Samira Musah
Publikováno v:
Bioengineering, Vol 9, Iss 5, p 188 (2022)
Podocytes derived from human induced pluripotent stem (hiPS) cells are enabling studies of kidney development and disease. However, many of these studies are carried out in traditional tissue culture plates that do not accurately recapitulate the mol
Externí odkaz:
https://doaj.org/article/4b446be92716453a9c7b3b4be2b53703
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Kinetoplastids are unicellular, eukaryotic, flagellated protozoans containing the eponymous kinetoplast. Within this order, the family of trypanosomatids are responsible for some of the most serious human diseases, including Chagas disease (Trypanoso
Externí odkaz:
https://doaj.org/article/6dd1e5d3579e4c638e69fb1f2e0dd1bf
Autor:
Morgan A. Burt, Titilola D. Kalejaiye, Rohan Bhattacharya, Nikolaos Dimitrakakis, Samira Musah
Publikováno v:
ACS Chemical Biology. 17:3341-3351
The most severe forms of kidney diseases are often associated with irreversible damage to the glomerular podocytes, the highly specialized epithelial cells that encase glomerular capillaries and regulate the removal of toxins and waste from the blood
Autor:
Guy Caljon, Louis Maes, Geert Jan Sterk, Maria de Nazaré Correia Soeiro, Raiza Brandão Peres, Titilola D. Kalejaiye, Julianna Siciliano de Araújo, Rob Leurs, Patrícia Bernardino da Silva, Marcos Meuser Batista, Harry P. de Koning
Publikováno v:
De Araújo, J S, Peres, R B, Da Silva, P B, Batista, M M, Sterk, G J, Maes, L, Caljon, G, Leurs, R, De Koning, H P, Kalejaiye, T D & De Nazaré Correia Soeiro, M 2021, ' Tetrahydrophthalazinone inhibitor of phosphodiesterase with in vitro activity against intracellular trypanosomatids ', Antimicrobial agents and chemotherapy, vol. 65, no. 3, e00960-20, pp. 1-5 . https://doi.org/10.1128/AAC.00960-20
Antimicrob Agents Chemother
Antimicrobial agents and chemotherapy, 65(3):e00960-20, 1-5. American Society for Microbiology
Antimicrobial agents and chemotherapy
Antimicrob Agents Chemother
Antimicrobial agents and chemotherapy, 65(3):e00960-20, 1-5. American Society for Microbiology
Antimicrobial agents and chemotherapy
The phosphodiesterase inhibitor tetrahydrophthalazinone NPD-008 was explored by phenotypic in vitro screening, target validation, and ultrastructural approaches against Trypanosoma cruzi . NPD-008 displayed activity against different forms and strain
Podocytes play an important role in maintaining the function of the glomerulus, and their loss or dysfunction contribute to the initiation and progression of kidney disease. The tissue interface consisting of podocytes and fenestrated endothelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b6dc0d496338880bc6e1e77cf4a0641
https://doi.org/10.1016/b978-0-12-823318-4.00007-x
https://doi.org/10.1016/b978-0-12-823318-4.00007-x
Autor:
Anupam Agarwal, Sophie L. Ashley, Amish Asthana, Anthony Atala, Janka Babickova, David P. Baird, David P. Basile, Ira Bedzow, Rohan Bhattacharya, Ulrich Blank, Joseph V. Bonventre, Nica M. Borradaile, Selin Celikoyar, Nicolas Charles, Matthew D. Cheung, Hoon Young Choi, Amanda E. Crunk, Eric Daugas, Benjamin Dekel, Marco Demaria, Danielle Diegisser, Feng Ding, Ercument Dirice, Ross Doyle, Thomas Ebert, Elise N. Erman, David A. Ferenbach, Agnes B. Fogo, Maria Giovanna Francipane, James F. George, Catherine Godson, Ladan Golestaneh, Michael S. Goligorsky, Dylan Haber, John Cijiang He, Daniel A. Heller, Jordan A. Holmes, Neil A. Hukriede, Joshua Hunsberger, Juan Carlos Izpisua Belmonte, Edgar A. Jaimes, Jing Ji, Sevim Kahraman, Titilola D. Kalejaiye, Chintan Kapadia, Matthias Kretzler, Catherine La Pointe, Laura Lasagni, Jason J. Lee, Kyung Lee, Lilach O. Lerman, Li Li, Xuezhu Li, Gretchen J. Mahler, Domenica Ida Marino, Benedetta Mazzinghi, A. Melk, Sean Muir, Samira Musah, Meryl C. Nath, Jamil Nehme, Joel Neugarten, Paola Nicolas, Mark D. Okusa, Giuseppe Orlando, Kenji Osafune, Hyeong Cheon Park, J. Geoffrey Pickering, Oren Pleniceanu, Aneta Przepiorski, May M. Rabadi, Brian B. Ratliff, Paola Romagnani, Jennifer A. Schaub, R. Schmitt, Sita Somara, Peter Stenvinkel, Marta Varela-Eirin, Ryan M. Williams, Rachel B. Wilson, Adrian S. Woolf, Yun Xia, Hai-Chun Yang, Li Yang, Mervin C. Yoder, Stephanie Zhang, Yuanyuan Zhang, Xiang Yang Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::248a93a75fed308b899898d38eebfdd8
https://doi.org/10.1016/b978-0-12-823318-4.09989-3
https://doi.org/10.1016/b978-0-12-823318-4.09989-3
Autor:
T. Travieso, Xingrui Mou, Samira Musah, Arinze E. Okafor, Maria Blasi, Rohan Bhattacharya, Titilola D. Kalejaiye, Morgan A. Burt
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the Coronavirus disease 2019 (COVID-19), which was declared a pandemic by the World Health Organization (WHO) in March 2020. The disease has caused more than 5.1 million de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d960ccdb19c38040dbbeb10635db189
https://doi.org/10.1101/2021.11.16.468893
https://doi.org/10.1101/2021.11.16.468893
Autor:
Erik de Heuvel, Abhimanyu K. Singh, Ewald Edink, Tiffany van der Meer, Melanie van der Woude, Payman Sadek, Mikkel P. Krell-Jørgensen, Toine van den Bergh, Johan Veerman, Guy Caljon, Titilola D. Kalejaiye, Maikel Wijtmans, Louis Maes, Harry P. de Koning, Geert Jan Sterk, Marco Siderius, Iwan J.P. de Esch, David G. Brown, Rob Leurs
Publikováno v:
Bioorganic and Medicinal Chemistry, 27(18), 3998-4012. Elsevier Limited
de Heuvel, E, Singh, A K, Edink, E, van der Meer, T, van der Woude, M, Sadek, P, Krell-Jørgensen, M P, van den Bergh, T, Veerman, J, Caljon, G, Kalejaiye, T D, Wijtmans, M, Maes, L, de Koning, H P, Jan Sterk, G, Siderius, M, de Esch, I J P, Brown, D G & Leurs, R 2019, ' Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors ', Bioorganic and Medicinal Chemistry, vol. 27, no. 18, pp. 3998-4012 . https://doi.org/10.1016/j.bmc.2019.06.027
de Heuvel, E, Singh, A K, Edink, E, van der Meer, T, van der Woude, M, Sadek, P, Krell-Jørgensen, M P, van den Bergh, T, Veerman, J, Caljon, G, Kalejaiye, T D, Wijtmans, M, Maes, L, de Koning, H P, Jan Sterk, G, Siderius, M, de Esch, I J P, Brown, D G & Leurs, R 2019, ' Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors ', Bioorganic and Medicinal Chemistry, vol. 27, no. 18, pp. 3998-4012 . https://doi.org/10.1016/j.bmc.2019.06.027
Several 3',5'-cyclic nucleotide phosphodiesterases (PDEs) have been validated as good drug targets for a large variety of diseases. Trypanosoma brucei PDEB1 (TbrPDEB1) has been designated as a promising drug target for the treatment of human African
Autor:
Rohan Bhattacharya, Xingrui Mou, Titilola D. Kalejaiye, Samira Musah, Arinze E. Okafor, Tatiana Travieso, Morgan A. Burt, Maria Blasi
Publikováno v:
SSRN Electronic Journal.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the Coronavirus disease 2019 (COVID-19), which was declared a pandemic by the World Health Organization (WHO) in March 2020. The disease has killed more than 3.8 million people world