Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tithi Ghosh Halder"'
Autor:
Juhina Das, Saurav Bera, Nilanjan Ganguly, Ipsita Guha, Tithi Ghosh Halder, Avishek Bhuniya, Partha Nandi, Mohona Chakravarti, Sukanya Dhar, Anirban Sarkar, Tapasi Das, Saptak Banerjee, Sandip Ghose, Anamika Bose, Rathindranath Baral
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMurine tumor growth restriction by neem leaf glycoprotein (NLGP) was established in various transplanted models of murine sarcoma, melanoma and carcinoma. However, the role of NLGP in the sequential carcinogenic steps has not been explore
Externí odkaz:
https://doaj.org/article/135df3f8dc1c4a1a8b7e8e4a38eabc10
Autor:
Raffaella Soldi, Tithi Ghosh Halder, Alexis Weston, Trason Thode, Kevin Drenner, Rhonda Lewis, Mohan R Kaadige, Shreyesi Srivastava, Sherin Daniel Ampanattu, Ryan Rodriguez Del Villar, Jessica Lang, Hariprasad Vankayalapati, Bernard Weissman, Jeffrey M Trent, William P D Hendricks, Sunil Sharma
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235705 (2020)
Mutations of the SWI/SNF chromatin remodeling complex occur in 20% of all human cancers, including ovarian cancer. Approximately half of ovarian clear cell carcinomas (OCCC) carry mutations in the SWI/SNF subunit ARID1A, while small cell carcinoma of
Externí odkaz:
https://doaj.org/article/1c9aae36c158461f9a747a08ebf0de0f
Autor:
Sunil Sharma, Monil Shah, Alexis Weston, Trason Thode, Serina Ng, Tithi Ghosh-Halder, Katelyn Gutowsky, Brian Durbin, Raffaella Soldi, Jonathan Northrup, Srinivas Kasibhatla, Mohan Kaadige
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/1e826d4302c24616afdbd6ca82d5d3d8
Autor:
Stephen K. Horrigan, Trason Thode, Serina Ng, Sunil Sharma, Ravi Salgia, Hariprasad Vankayalapati, Kevin Drenner, Raffaella Soldi, Mohan R. Kaadige, Samuel Sampson, Ryan Rodriguez del Villar, Surinder K. Batra, Alexis Weston, Tithi Ghosh Halder, Kapil N. Bhalla
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 378:77-86
The central role of β-catenin in the Wnt pathway makes it an attractive therapeutic target for cancers driven by aberrant Wnt signaling. We recently developed a small-molecule inhibitor, BC-2059, that promotes apoptosis by disrupting the β-catenin/
Autor:
Alexis S. Weston, Trason Thode, Serina Ng, Tithi Ghosh-Halder, Shelby Rheinschmidt, Sydney Adamson, Katelyn Gutowsky, Brian Durbin, Raffaella Soldi, Srinivas Kasibhatla, Mohan Kaadige, Sunil Sharma
Publikováno v:
Cancer Research. 83:LB323-LB323
Purpose: It has become increasingly clear that the activation of both the innate and adaptive immune systems is vital to provide the best outcomes with immunotherapies. As part of the adaptive immune response, checkpoint inhibitors (CIs) have shown p
Autor:
Trason Thode, Alexis Weston, Serina Ng, Shelby Rheinschmidt, Tithi Ghosh Halder, Sydney Adamson, Kate Gutowsky, Brian Durbin, Raffaella Soldi, Mohan Kaadige, Srinivas Kasibhatla, Haiyong Han, Justin Moser, Vincent Chung, Joseph Chao, Victoria Villaflor, Daniel D. Von Hoff, Sunil Sharma
Publikováno v:
Cancer Research. 83:2688-2688
Purpose: Head and Neck Squamous Cell Carcinoma (HNSCC) is the 6th most prevalent type of cancer in the world with incidence rates projected to increase 30% by 2030. This increase is generally associated with cultural and environmental risk factors su
Autor:
Tithi Ghosh Halder, Shelby Rheinschmidt, Sydney Adamson, Anna Larson, Taylor Bargenquast, Ryan Rodriguez del Villar, Serina Ng, Kate Gutowsky, Alexis Weston, Trason Thode, Mohan Kaadige, Erin Kelley, Jorge Soria-Bustos, Jorge Giron, John Altin, Raffaella Soldi, Sunil Sharma
Publikováno v:
Cancer Research. 83:4060-4060
Background: Immunotherapies using autologous tumor infiltrating lymphocytes (TILs) have become effective treatment modalities for several patients with solid tumors, yielding a response rate of around 49% in patients with metastatic melanoma. Most cl
Autor:
Anna Larson, Taylor Bargenquast, Sara Byron, Anish Raju, Avijit Podder, Shelby Rheinschmidt, Tithi Ghosh Halder, Samuel Sampson, Sydney Adamson, Serina Ng, Kate Gutowsky, Alexis Weston, Trason Thode, Justin Moser, Erkut Borazanci, Mohan Kaadige, Nicholas Schork, Raffaella Soldi, Sunil Sharma
Publikováno v:
Cancer Research. 83:1069-1069
Background: Cancer therapy has witnessed great progress over the last 50 years with advancements in diagnostic tools to enable more precise treatment. With the development of next-generation sequencing, the field of precision oncology has been expand
Publikováno v:
Current opinion in oncology. 33(5)
Purpose of review Bromodomain and extraterminal domain (BET) proteins are evolutionarily conserved, multifunctional super-regulators that specifically recognize acetyl-lysine on histones and other proteins controlling gene transcription. Several stud
Autor:
Alexis Weston, Trason Thode, Ryan Rodriguez del Villar, Serina Ng, Samuel Sampson, Shelby Rheinschmidt, Tithi Ghosh Halder, Raffaella Soldi, Mohan Kaadige, Srinivas Kasibhatla, Haiyong Han, Justin Moser, Vincent Chung, Joseph Chao, Victoria Villaflor, Daniel Von Hoff, Sunil Sharma
Publikováno v:
Cancer Research. 82:3931-3931
Purpose: Overexpression of Cyclin-Dependent Kinase 7 (CDK7) is linked to poor clinical outcomes in a variety of cancer types including AML, breast, ovarian, pancreatic, and lung cancers. CDK7 plays a dual role in tumor progression by regulating the c