Sickle cell anemia and pregnancy: Profile of hemodynamic changes in sickle cell pregnant women in Kinshasa

Autor: Tite Minga Mikobi, Nelly Ciombo Kamuanya, Emmanuelle Ketsia Bokashanga Mikobi, Thérèse Ilunga Kalela, Pierre Zalagile Akilimali, Prosper Tshilobo Lukusa

Publikováno v: eJHaem, Vol 4, Iss 4, Pp 977-983 (2023)

Abstract Pregnancy is accompanied by hormonal changes. These relate mainly to progesterone and placenate growth factor. Hemodynamic changes are also observed. in a sickle cell pregnant woman, all these changes have a direct effect on hypoxia. This is

Externí odkaz: https://doaj.org/article/816ec4bac0f6410dab214ec3d08eddb6

Clinical and biological profile of Sickle Cell Anemia children in a rural area in Central Africa

Autor: Gloire Mbayabo, Mamy Ngole, Paul Kabuyi Lumbala, Aimé Lumaka, Valerie Race, Gert Matthijs, Tite Minga Mikobi, Koenraad Devriendt, Chris Van Geet, Prosper Tshilobo Lukusa

Publikováno v: Hematology, Vol 28, Iss 1 (2023)

ABSTRACTBackground: Sickle Cell Anemia (SCA) is the most common genetic disease worldwide caused by a single mutation in the gene HBB. The disease severity is very variable and depends on many factors. We evaluated the clinical and biological profile

Externí odkaz: https://doaj.org/article/34f2e67d7afd4d9691ea584959c2579a

Sickle cell disease and pregnancy profile of complicated malaria in 982 pregnancies in Kinshasa

Autor: Tite Minga Mikobi, Nelly Ciombo Kamuanya, Pierre Zalagile Akilimali, Prosper Tshilobo Lukusa

Publikováno v: PLoS ONE, Vol 17, Iss 10 (2022)

Introduction Malaria is associated with high morbidity during pregnancy. Homozygous sickle cell pregnant women are even more exposed during complicated malaria. The objective of the study was to evaluate the maternal and fetal morbidity of homozygous

Externí odkaz: https://doaj.org/article/40e1bb4ec5c6479785872f5866881ccf

Correlation between the Lactate Dehydrogenase Levels with Laboratory Variables in the Clinical Severity of Sickle Cell Anemia in Congolese Patients.

Autor: Tite Minga Mikobi, Prosper Lukusa Tshilobo, Michel Ntetani Aloni, Georges Mvumbi Lelo, Pierre Zalagile Akilimali, Jean Jacques Muyembe-Tamfum, Valérie Race, Gert Matthijs, Jean Marie Mbuyi Mwamba

Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0123568 (2015)

BackgroundSickle cell anemia is an inflammatory disease and is characterized by chronic hemolysis. We sought to evaluate the association of lactate dehydrogenase levels with specific clinical phenotypes and laboratory variables in patients with sickl

Externí odkaz: https://doaj.org/article/3baf3175cee449f493cbded23cf7cf69

HOMOZYGOUS DELETION ALFA-THALASSEMIA AND HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN, TWO GENETIC FACTORS PREDICTIVE THE REDUCTION OF MORBIDITY AND MORTALITY DURING PREGNANCY IN SICKLE CELL PATIENTS . A REPORT FROM DEMOCRATIC REPUBLIC OF CONGO

Autor: Tozin Rhama, Tite Minga Mikobi, Jean-Marie Mbuyi Muamba, Prosper Lukusa

Publikováno v: Mediterranean Journal of Hematology and Infectious Diseases, Vol 11, Iss 1 (2019)
Mediterranean Journal of Hematology and Infectious Diseases

FHb and alpha-thal are two genetic factors that modulate the clinical expression of sickle cell disease. Objective: to determine the beneficial role of FHb and alpha-thal on fetal and maternal morbidity during pregnancy in sickle cell patients. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd12206c537306abdb040d3e6e97599
https://doi.org/10.4084/mjhid.2019.039