Výsledky vyhledávání - "Tissue-Specific Progenitor and Stem Cells"

Role of extracellular vesicles from adipose tissue‐ and bone marrow‐mesenchymal stromal cells in endothelial proliferation and chondrogenesis

Autor: Cansu Gorgun, Daniele Reverberi, Roberta Tasso, Maria Elisabetta Federica Palamà, Katia Cortese, Maria Cristina Gagliani, Chiara Gentili

Publikováno v: Stem Cells Translational Medicine, Vol 10, Iss 12, Pp 1680-1695 (2021)
Stem Cells Translational Medicine
STEM CELLS Transl Med

The secretome of mesenchymal stromal cells (MSCs) derived from different tissue sources is considered an innovative therapeutic tool for regenerative medicine. Although adipose tissue‐and bone marrow‐derived MSCs (ADSCs and BMSCs, respectively) s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6141afe074d75e679a942c50cbe85b5
https://doaj.org/article/bd560bce184d4dddbc45f57b68cac4a9

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Repeated Injury Promotes Tracheobronchial Tissue Stem Cell Attrition

Autor: Saranga Wijeratne, Don Hayes, Moumita Ghosh, Alfahdah Alsudayri, Susan D. Reynolds, Barry R. Stripp, Zhang Hong Tan, Cynthia L Hill, Tendy Chiang, Gianni Carraro, John Mahoney, Scott W. Lallier

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 12, Pp 1696-1713 (2021)

Chronic lung disease has been attributed to stem cell aging and/or exhaustion. We investigated these mechanisms using mouse and human tracheobronchial tissue‐specific stem cells (TSC). In mouse, chromatin labeling and flow cytometry demonstrated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8823b91f5178d66d0051a8722b992919
https://doi.org/10.1002/sctm.21-0032

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Ferulic acid promotes bone defect repair after radiation by maintaining the stemness of skeletal stem cells

Autor: Song Liao, Wei Hu, Zhi-Ling Li, Zhi-Dong Zhao, Qian Wang, Jia-Wu Liang, Pei-Lin Li, Bo-Feng Yin, Li Ding, Ning Mao, Heng Zhu

Publikováno v: Stem Cells Translational Medicine, Vol 10, Iss 8, Pp 1217-1231 (2021)
Stem Cells Translational Medicine

The reconstruction of irradiated bone defects after settlement of skeletal tumors remains a significant challenge in clinical applications. In this study, we explored radiation‐induced skeletal stem cell (SSC) stemness impairments and rescuing effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcf85a2e1343a436958ad68bf9627dc
https://doaj.org/article/34bc7f5a1d7a47c096bc0f73aae0cabb

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Type II collagen‐positive embryonic progenitors are the major contributors to spine and intervertebral disc development and repair

Autor: Shuying Yang, Shuting Yang, Xinhua Li, Ling Qin

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 10, Pp 1419-1432 (2021)

Basic mechanism of spine development is poorly understood. Type II collagen positive (Col2+) cells have been reported to encompass early mesenchymal progenitors that continue to become chondrocytes, osteoblasts, stromal cells, and adipocytes in long

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a411f3e784ba5a3c92125791bf06ca5
http://europepmc.org/articles/PMC8459639

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The secretome of liver X receptor agonist‐treated early outgrowth cells decreases atherosclerosis in Ldlr−/− mice

Autor: Adil Rasheed, Katey J. Rayner, Benjamin Hibbert, Trevor Simard, Sarah A. Shawky, Ricky Tsai, Richard G. Jung, Carolyn L. Cummins, Michael F. Saikali

Publikováno v: Stem Cells Translational Medicine, Vol 10, Iss 3, Pp 479-491 (2021)
Stem Cells Translational Medicine

Endothelial progenitor cells (EPCs) promote the maintenance of the endothelium by secreting vasoreparative factors. A population of EPCs known as early outgrowth cells (EOCs) is being investigated as novel cell‐based therapies for the treatment of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e000667c769a32f9368bf863b77e4a99
https://doaj.org/article/3046695fb43846b1836880d2cf1f986b

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Neural crest-derived mesenchymal progenitor cells enhance cranial allograft integration

Autor: Zulma Gazit, Wafa Tawackoli, Robert H. Baloh, Melodie F. Metzger, Angela Papalamprou, Juliane D. Glaeser, Samuel Eberlein, Tina Stefanovic, Trevor J. Nelson, Doron Cohn‐Schwartz, Shiran Ben-David, Dmitriy Sheyn, Khosrowdad Salehi, Robert K. Ryu, Kevin J. Kim, Hyun W. Bae, Yasaman Arabi, Phillip H. Behrens

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 797-809 (2021)

Replacement of lost cranial bone (partly mesodermal and partly neural crest‐derived) is challenging and includes the use of nonviable allografts. To revitalize allografts, bone marrow‐derived mesenchymal stromal cells (mesoderm‐derived BM‐MSC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c283eaec32281621329a270fefe6036
https://doi.org/10.1002/sctm.20-0364

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A replicating stem‐like cell that contributes to bone morphogenetic protein 2‐induced heterotopic bone formation

Autor: Zbigniew Gugala, Elizabeth A. Olmsted-Davis, Alan R. Davis, Julio Mejia, Elizabeth Salisbury, Corinne Sonnet

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 4, Pp 623-635 (2021)

Bone morphogenetic protein 2 (BMP2)‐induced heterotopic bone formation (HBF) starts synchronously from zero upon BMP2 induction, which is advantageous for lineage tracking. The studies reported here in GLAST‐CreErt2:tdTomato red (TR)floxSTOPflox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5acb9d235dfe9b8306686dcd9133af95
http://europepmc.org/articles/PMC7980206

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Conjunctival reconstruction via enrichment of human conjunctival epithelial stem cells by p75 through the NGF‐p75‐SALL2 signaling axis

Autor: Junzhao Chen, Fei Yu, Qinke Yao, Hao Sun, Chenxi Yan, Nianxuan Wu, Yao Fu, Yang Lu

Publikováno v: Stem Cells Translational Medicine, Vol 9, Iss 11, Pp 1448-1461 (2020)
Stem Cells Translational Medicine

Severe conjunctival diseases can cause significant conjunctival scarring, which seriously limits eye movement and affects patients' vision. Conjunctival reconstruction remains challenging due to the lack of efficient methods for stem cells enrichment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b0d062b14b9d24cf7af1eb271556d3
https://doaj.org/article/de4b25dd56334ffd822cdccd51698d96

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Advances in preclinical hematopoietic stem cell models and possible implications for improving therapeutic transplantation

Autor: Maria Feliz Norberto, Kathryn S. Potts, Teresa V. Bowman, Bianca A. Ulloa, Ellen Fraint

Publikováno v: Stem Cells Translational Medicine, Vol 10, Iss 3, Pp 337-345 (2021)
Stem Cells Translational Medicine

Hematopoietic stem cell transplantation (HSCT) is a treatment for many malignant, congenital, and acquired hematologic diseases. Some outstanding challenges in the HSCT field include the paucity of immunologically‐matched donors, our inability to e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4bb1fba537a76234762bccc9f77b62
https://doi.org/10.1002/sctm.20-0294

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Sensory nerves in the spotlight of the stem cell niche

Autor: Alexander Birbrair, Thiago M. Cunha, Rodrigo R. Resende, Pedro H.D.M. Prazeres, Beatriz G S Rocha, Anderson Oropeza, Pedro A C Costa, Vasco Azevedo, Akiva Mintz, Walison N. Silva, Gabryella S P Santos, Caroline C. Picoli, Rodrigo A. da Silva, Alinne C. Costa

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 3, Pp 346-356 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Niches are specialized tissue microenvironments that control stem cells functioning. The bone marrow mesenchymal stem cell niche defines a location within the marrow in which mesenchymal stem cells are retained and produce new cells throughout life.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cbca69a3d5dbadd99f09aab09bb106
http://europepmc.org/articles/PMC7900586

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