Zobrazeno 1 - 10
of 18 394
pro vyhledávání: '"Tissue microarray"'
Autor:
Alexandre deNonneville, Elsa Kalbacher, Francesco Cannone, Arnaud Guille, José Adelaïde, Pascal Finetti, Maria Cappiello, Eric Lambaudie, Giuseppe Ettore, Emmanuelle Charafe, Emilie Mamessier, Magali Provansal, François Bertucci, Renaud Sabatier
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2586-2600 (2024)
Endometrioid ovarian cancers (EOvC) are usually managed as serous tumors. In this study, we conducted a comprehensive molecular investigation to uncover the distinct biological characteristics of EOvC. This retrospective multicenter study involved pa
Externí odkaz:
https://doaj.org/article/7e6216ea4f234271b8862b530fe72449
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Blacks/African American (BAA) patients diagnosed with head and neck squamous cell carcinoma (HNSCC) have worse survival outcomes than White patients. However, the mechanisms underlying racial disparities in HNSCC have not been tho
Externí odkaz:
https://doaj.org/article/2cd138a31c8d40ac99820dee8f89fef9
Autor:
Renan Gomes do Nascimento, Mércia Patrícia Ferreira da Conceição, Daniel Rodrigues de Bastos, Cynthia Aparecida Bueno de Toledo Osorio, Rossana Verónica Mendoza López, Eduardo Moraes Reis, Otto Luiz Dutra Cerqueira
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The search for prognostic markers in breast cancer has bumped into a typical feature of these tumors, intra and intertumoral heterogeneity. Changes in the expression profile, localization of these proteins or shedding to the surrounding stro
Externí odkaz:
https://doaj.org/article/6328f6277bc949a4b097a3f377ad88bf
Autor:
Simon Kind, Carolina Palacios Castillo, Ria Schlichter, Natalia Gorbokon, Maximilian Lennartz, Lisa S. Hornsteiner, Sebastian Dwertmann Rico, Viktor Reiswich, Florian Viehweger, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Franziska Büscheck, Till S. Clauditz, Christoph Fraune, Andrea Hinsch, Till Krech, Patrick Lebok, Stefan Steurer, Eike Burandt, Sarah Minner, Andreas H. Marx, Ronald Simon, Waldemar Wilczak, Guido Sauter, Anne Menz, Frank Jacobsen
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and thus plays a pivotal role in maintaining skin homeostasis. In cancer, KLK7 overexpression was
Externí odkaz:
https://doaj.org/article/5ac61efaf1d649688eb409482a34a7c5
Autor:
Henning Plage, Kira Furlano, Jörg Neymeyer, Sarah Weinberger, Benedikt Gerdes, Mandy Hubatsch, Bernhard Ralla, Antonia Franz, Annika Fendler, Michela deMartino, Florian Roßner, Simon Schallenberg, Sefer Elezkurtaj, Martina Kluth, Maximilian Lennartz, Niclas C. Blessin, Andreas H. Marx, Henrik Samtleben, Margit Fisch, Michael Rink, Krystian Kaczmarek, Thorsten Ecke, Steffen Hallmann, Stefan Koch, Nico Adamini, Sarah Minner, Ronald Simon, Guido Sauter, Joachim Weischenfeldt, Tobias Klatte, Thorsten Schlomm, David Horst, Henrik Zecha, Marcin Slojewski
Publikováno v:
BJUI Compass, Vol 5, Iss 6, Pp 585-592 (2024)
Abstract Objectives Carcinoembryonic antigen (CEA) is a cell surface glycoprotein that represents a promising therapeutic target. Serum measurement of shedded CEA can be utilized for monitoring of cancer patients. Material and Methods To evaluate the
Externí odkaz:
https://doaj.org/article/81a61db9b6264355b1ed85e97fb6d1fe
Autor:
Lore De Cock, Flavia Paternostro, Ulla Vanleeuw, Karo Wyns, Annouschka Laenen, Che-Jui Lee, Raf Sciot, Agnieszka Wozniak, Patrick Schöffski
Publikováno v:
Translational Oncology, Vol 48, Iss , Pp 102057- (2024)
Background: Synovial sarcoma (SynSa) is one of the most common translocation-related soft tissue sarcomas. Patients with metastatic SynSa have limited treatment options and a very poor prognosis. Several novel experimental therapies are currently bei
Externí odkaz:
https://doaj.org/article/1849db8fb1904ffe95310ec132df2b55
Autor:
Asaf Dan, Ozan Aricak, Konstantinos Rounis, M. Angeles Montero-Fernandez, Ricardo Guijarro, Simon Ekman, Cristian Ortiz-Villalón, Luigi De Petris
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionProgrammed death ligand – 1 (PD-L1) expression is a well-established predictive biomarker for immunotherapy in non-small cell lung cancer (NSCLC). Programmed death – 1 (PD-1) serves as the target protein to PD-L1 and their interaction
Externí odkaz:
https://doaj.org/article/6bc2bad02c314212b6aa290293416a85
Autor:
Henning Plage, Kira Furlano, Sebastian Hofbauer, Sarah Weinberger, Bernhard Ralla, Antonia Franz, Annika Fendler, Michela de Martino, Florian Roßner, Sefer Elezkurtaj, Martina Kluth, Maximilian Lennartz, Niclas C. Blessin, Andreas H. Marx, Henrik Samtleben, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek, Thorsten Ecke, Steffen Hallmann, Stefan Koch, Nico Adamini, Henrik Zecha, Sarah Minner, Ronald Simon, Guido Sauter, Joachim Weischenfeldt, Tobias Klatte, Thorsten Schlomm, David Horst, Simon Schallenberg
Publikováno v:
BMC Urology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background A high level of PD-L1 expression is the most relevant predictive parameter for response to immune checkpoint inhibitor (CPI) therapy in urinary bladder cancer. Existing data on the relationship between PD-L1 expression and the nat
Externí odkaz:
https://doaj.org/article/2e11c11592e44f26b250abef630710aa
Autor:
Jiakuan Peng, Ziang Xu, Hongxia Dan, Jing Li, Jiongke Wang, Xiaobo Luo, Hao Xu, Xin Zeng, Qianming Chen
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background The grading of oral epithelial dysplasia is often time-consuming for oral pathologists and the results are poorly reproducible between observers. In this study, we aimed to establish an objective, accurate and useful detection and
Externí odkaz:
https://doaj.org/article/54f30781695940e098dc699ed0ca4d8a
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 04, Pp 01-06 (2024)
Introduction: Tissue Microarray (TMA) is a novel technique that is now integral in pre-clinical and translational research. In resource-limited settings, automated microarrayers and molds are out of reach, and manual TMA construction may be done inst
Externí odkaz:
https://doaj.org/article/afb8a8c686014281bebbbcfad091876b