Single cell RNA sequencing of the native human liver and its spatial resolution reveal new subpopulations of non-parenchymal cells

Autor: Payen, Valéry, Lavergne, A., Charloteaux, B, Alevra Sarika, Niki, Karim, L., Deckers, M., Najimi, Mustapha, Smets, Françoise, Jazouli, Nawal, Coppieters, W., Georges, M., Sokal, Etienne, El Taghdouini, Adil, Keystone Symposia : Fibrosis and tissue repair from molecules and mechanics to therapeutic approaches.

Background: The liver’s multitude of vital functions are tightly linked to its complex assembly of highly specialized parenchymal and non-parenchymal cells in collaborative sinusoidal units. In the present study we aimed at providing the first high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1493::6346e8d26950cb929ead147f7fc2dab3
https://hdl.handle.net/2078.1/227452

A cell-type-specific role for murine Commd1 in liver inflammation

Autor: Bartuzi, Paulina, Wijshake, Tobias, Dekker, Daphne C, Fedoseienko, Alina, Kloosterhuis, Niels J, Youssef, Sameh A, Li, Haiying, Shiri-Sverdlov, Ronit, Kuivenhoven, Jan-Albert, de Bruin, Alain, Burstein, Ezra, Hofker, Marten H, van de Sluis, Bart, LS Pathobiologie, Tissue Repair, PB TR

Publikováno v: Biochimica et Biophysica Acta, 1842(11), 2257
Biochimica et biophysica acta-Molecular basis of disease, 1842(11), 2257-2265. ELSEVIER SCIENCE BV
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1842(11), 2257-2265. Elsevier Science

The transcription factor NF-kappa B plays a critical role in the inflammatory response and it has been implicated in various diseases, including non-alcoholic fatty liver disease (NAFLD). Although transient NF-kappa B activation may protect tissues f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd2e67475f61ab54b589037e78df498
https://doi.org/10.1016/j.bbadis.2014.06.035

Ethical implications of regenerative medicine in orthopedics: an empirical study with surgeons and scientists in the field

Autor: Niemansburg, Sophie L, van Delden, Johannes J M, Oner, F Cumhur, Dhert, Wouter J A, Bredenoord, Annelien L, Faculteit Diergeneeskunde, LS Equine Muscoskeletal Biology, Onderzoek, Tissue Repair, CSCA TR1

Publikováno v: The Spine Journal, 14(6), 1029. Elsevier

Background context Regenerative medicine (RM) interventions, such as (stem) cell transplantation, scaffolds, gene transfer, and tissue engineering, are likely to change the field of orthopedics considerably. These strategies will significantly differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470c92c28a8a8fffd3d04affb72f2107
https://doi.org/10.1016/j.spinee.2013.10.016

Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease

Autor: Sheedfar, Fareeba, Sung, Miranda My, Aparicio-Vergara, Marcela, Kloosterhuis, Niels J, Miquilena-Colina, Maria Eugenia, Vargas-Castrillón, Javier, Febbraio, Maria, Jacobs, René L, de Bruin, Alain, Vinciguerra, Manlio, García-Monzón, Carmelo, Hofker, Marten H, Dyck, Jason Rb, Koonen, Debby P Y, LS Pathobiologie, PB TR, Tissue Repair

Publikováno v: Aging-Us, 6(4), 281-295. Impact Journals LLC
Aging (Albany, N.Y.), 6, 281-95
Aging (Albany NY)
Aging (Albany, N.Y.), 6, 4, pp. 281-95
Aging, 6(4), 281. US Administration on Aging
Scopus-Elsevier

Item does not contain fulltext CD36 has been associated with obesity and diabetes in human liver diseases, however, its role in age-associated nonalcoholic fatty liver disease (NAFLD) is unknown. Therefore, liver biopsies were collected from individu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c12d6676b91a757b5fe77cdede5962
https://doi.org/10.18632/aging.100652

Identification of a novel kisspeptin with high gonadotrophin stimulatory activity in the dog

Autor: Albers-Wolthers, Karin H J, de Gier, Jeffrey, Kooistra, Hans S, Rutten, Victor P M G, van Kooten, Peter J S, de Graaf, Janneke J, Leegwater, Peter A J, Millar, Robert P, Schaefers-Okkens, Auke C, CSCA AVM, Advances in Veterinary Medicine, I&I RATIA-SIB, Sub Voortplanting, Sub Endocrinologie, LS Immunologie, Onderzoek, Tissue Repair, CSCA TR1

Publikováno v: Neuroendocrinology
Neuroendocrinology, 99(3-4), 178. S. Karger AG

Kisspeptin (KISS1) and its receptor (KISS1r) are essential for normal reproductive function in many species, but the role of kiss1/kiss1r signalling in the dog has not yet been elucidated. The aims of this study were to identify the canine kiss1 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060cb3e462d8b78f604da6ae223842c7
http://www.ncbi.nlm.nih.gov/pubmed/24902774