Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tissue Plasminogen Activator/metabolism"'
Autor:
Michael S. Pepper, Lelio Orci, Roberto Montesano, Jean-Dominique Vassalli, Stefano J. Mandriota
Publikováno v:
Enzyme Protein, Vol. 49, No 1-3 (1996) pp. 138-162
Extracellular proteolysis is required for matrix degradation and the regulation of cytokine activity during angiogenesis, and this is dependent on a cohort of proteases and protease inhibitors produced by endothelial and nonendothelial cells. The pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11e8a4a101ddae18a87eeea19c31baa
https://doi.org/10.1159/000468622
https://doi.org/10.1159/000468622
Autor:
Eric Maubert, Richard Macrez, Jérôme Parcq, Fabian Docagne, Yannick Hommet, Maxime Gauberti, Carine Ali, Axel Montagne, Miriam Hernangómez, Carmen Guaza, Pauline Obiang, Géraldine Liot, Denis Vivien, Fernando Correa
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
The Journal of experimental medicine, 208 (6
The Journal of Experimental Medicine
instname
The Journal of experimental medicine, 208 (6
The Journal of Experimental Medicine
Tissue plasminogen activator (tPA) is the only available treatment for acute stroke. In addition to its vascular fibrinolytic action, tPA exerts various effects within the brain, ranging from synaptic plasticity to control of cell fate. To date, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2cef9d22e30360f840cf0f8a2d0b24
http://hdl.handle.net/10261/73294
http://hdl.handle.net/10261/73294
Autor:
Sanda Jelisavac Ćosić, Zdenko Kovač
Publikováno v:
Liječnički vjesnik
Volume 133
Issue 1-2
Volume 133
Issue 1-2
Pericelularna proteoliza složen je kaskadni proces razgradnje međustanične tvari, koji sudjeluje u fiziološkim i etiopatogenetskim procesima. Osim razgradnje tkivne strome i slabljenja međustaničnih sveza u tkivu, tom se proteolizom stvaraju bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______951::70bd4da044ca12ada9de2eee8cfb5325
https://hrcak.srce.hr/171655
https://hrcak.srce.hr/171655
Publikováno v:
Trends in Molecular Medicine, Vol. 9, No 5 (2003) pp. 183-5
Activity-dependent remodeling of neural connections might require localized extracellular proteolysis. The tissue-type plasminogen activator (tPA)-plasmin proteolytic system is expressed in different regions of the central nervous system, in the cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04cb386a2b88a275014e8a5fd8582dd
https://pubmed.ncbi.nlm.nih.gov/12763521
https://pubmed.ncbi.nlm.nih.gov/12763521
Autor:
Scherrer, Anne Paule Marie, Wohlwend, Annelise Isabelle, Kruithof, Egbert, Vassalli, Jean-Dominique, Sappino, Pascal
Publikováno v:
British Journal of Haematology, Vol. 105, No 4 (1999) pp. 920-7
Plasminogen activation is implicated in solid tumour growth, invasion and metatastic spread. However, little is known about its role in leukaemia. We investigated the production by leukaemic cells of plasminogen activators [urokinase (uPA) and tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::07b66b707211c32d9215f7e3f301ffe5
https://pubmed.ncbi.nlm.nih.gov/10554801
https://pubmed.ncbi.nlm.nih.gov/10554801
Autor:
C. Trân-Thang, Gian Dorta, P. Chaubert, E. Saraga, P. Protiva, I. Sordat, A. L. Blum, Bernard Sordat
Publikováno v:
British Journal of Cancer
British journal of cancer, vol. 77, no. 2, pp. 297-304
British journal of cancer, vol. 77, no. 2, pp. 297-304
Proteases are important for neoplastic invasion but a specific role for the plasminogen activator system in the progression of colorectal epithelial dysplasia to adenomatous lesions remains unclear. Consecutive tissue cryosections of 51 adenomas, 49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db368288ed723c24c70a6bf03bac7a46
https://pubmed.ncbi.nlm.nih.gov/9461001
https://pubmed.ncbi.nlm.nih.gov/9461001
Publikováno v:
Developmental Biology, Vol. 187, No 1 (1997) pp. 43-54
Full-grown mouse oocytes spontaneously resume meiosis in vitro when released from their follicular environment. By contrast, growing oocytes are not competent to resume meiosis; the molecular basis of meiotic competence is not known. Entry into M pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd8e7e48146751ce11ccd5021410da0
https://pubmed.ncbi.nlm.nih.gov/9224673
https://pubmed.ncbi.nlm.nih.gov/9224673
Publikováno v:
Cancer Research, Vol. 55, No 20 (1995) pp. 4688-4695
The expression of different components of the plasminogen activator (PA)/plasmin system was explored in a series of colorectal neoplasia. We have found that urokinase (uPA) and urokinase receptor (uPA-R) gene expression is upregulated in adenomas and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::baff67f4147b7e10c2186fab1ac22226
https://pubmed.ncbi.nlm.nih.gov/7553650
https://pubmed.ncbi.nlm.nih.gov/7553650
Autor:
Delbaldo, Catherine Suzanne, Masouyé, Isabelle, Saurat, Jean-Hilaire, Vassalli, Jean-Dominique, Sappino, Pascal
Publikováno v:
Cancer Research, Vol. 54, No 16 (1994) pp. 4547-4552
A large body of experimental evidence suggests that plasminogen activators provide tumoral cells with efficient means to degrade extracellular matrix constituents and thereby facilitate their dissemination to distant sites. Melanocytic neoplasia enco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b4ea7938a17f117664b6ffe776d86e98
https://pubmed.ncbi.nlm.nih.gov/8044805
https://pubmed.ncbi.nlm.nih.gov/8044805
Publikováno v:
Developmental Biology, Vol. 157, No 2 (1993) pp. 539-546
At the time of fertilization both murine gametes express plasminogen-dependent proteolytic activity: unfertilized eggs secrete tissue-type plasminogen activator and ejaculated spermatozoa have urokinase-type plasminogen activator bound to their surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1988fad0402bbbf1c2a29d7bb66a9785
https://pubmed.ncbi.nlm.nih.gov/8388818
https://pubmed.ncbi.nlm.nih.gov/8388818