Proof-of-Concept Study of the NOTI Chelating Platform: Preclinical Evaluation of 64Cu-Labeled Mono- and Trimeric c(RGDfK) Conjugates

Autor: Sebastian Martin, Stephan Maus, Samer Ezziddin, Fadi Khreish, Jason P. Holland, Tobias Stemler, Mark Bartholomä, Florian Rosar

Publikováno v: Molecular imaging and biology, vol. 23, no. 1, pp. 95-108

Purpose We recently developed a chelating platform based on the macrocycle 1,4,7-triazacyclononane with up to three five-membered azaheterocyclic arms for the preparation of 68Ga- and 64Cu-based radiopharmaceuticals. Based on this platform, the chela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0760ce1713c78e833f691ed39b2dc9e
https://serval.unil.ch/notice/serval:BIB_6D412B0B99D5

Development and validation of HPLC method with fluorometric detection for quantification of bisnaphthalimidopropyldiaminooctane in animal tissues following administration in polymeric nanoparticles

Autor: Sofia A. Costa Lima, Vera L.R.G. Abreu, Anabela Cordeiro-da-Silva, Sónia Nogueira, Paul Kong Thoo Lin, Marcela A. Segundo, Marcelo V. Osório

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

A simple, sensitive and specific high-performance liquid chromatography method for the quantification of bisnaphthalimidopropyldiaminooctane (BNIPDaoct), a potent anti-Leishmania compound, incorporated into poly(D,L-lactide-co-glycolic acid) (PLGA) n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563fcb5da5e1f3a99b98323a2eb4374d
https://repositorio-aberto.up.pt/handle/10216/118197

Stretch-induced inhibition of Wnt/beta-catenin signaling in mineralizing osteoblasts

Autor: Jansen, Justus H W, Eijken, Marco, Jahr, Holger, Chiba, Hideki, Verhaar, Jan A N, van Leeuwen, Johannes P T M, Weinans, Harrie

Publikováno v: Jansen, J H W, Eijken, M, Jahr, H, Chiba, H, Verhaar, J A N, van Leeuwen, J P T M & Weinans, H 2010, ' Stretch-induced inhibition of Wnt/beta-catenin signaling in mineralizing osteoblasts ', Journal of Orthopaedic Research, vol. 28, no. 3, pp. 390-6 . https://doi.org/10.1002/jor.20991

Wnt signaling is important for bone formation and osteoblastic differentiation. Recent findings indicate a stimulating role of Wnt signaling in bone mechanotransduction. However, negative effects of Wnt signaling on osteoblast differentiation and min

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::146772e100c150097a40c592dfc1b6a0
https://pure.au.dk/portal/da/publications/stretchinduced-inhibition-of-wntbetacatenin-signaling-in-mineralizing-osteoblasts(19b44743-284b-4524-9d05-29762dcf27e3).html

Effect of atorvastatin on the concentration, relative distribution, and chemical composition of lipoprotein subfractions in patients with dyslipidemias of type IIA and IIB

Autor: Moses Elisaf, Sonia-Athena P. Karabina, Eleni Bairaktari, Apostolos Achimastos, Vasilis Tsimihodimos, Afroditi P. Tambaki, Alexandros D. Tselepis

Publikováno v: Journal of cardiovascular pharmacology. 42(2)

The authors investigated the effect of atorvastatin (40 mg qd) on low-density lipoprotein (LDL) particle distribution in patients with dyslipidemias of type IIA (n = 55) and IIB (n = 21). Atorvastatin therapy induced a significant decrease in total a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e021d528fc3954db6cf133631afddf
https://pubmed.ncbi.nlm.nih.gov/12883336