ANO4 (Anoctamin 4) is a novel marker of zona glomerulosa that regulates stimulated aldosterone secretion

Autor: Morris J. Brown, Luis J. V. Galietta, Paolo Scudieri, Lalarukh Haris Shaikh, Wanfeng Zhao, Mark Gurnell, Carmela Maniero

Publikováno v: Hypertension (Dallas, Tex. : 1979)

Supplemental Digital Content is available in the text.
Microarray comparison of the transcriptomes of human adrenal zona glomerulosa (ZG) and zona fasciculata found several ZG-specific genes that negatively regulate aldosterone secretion. The th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d927d42032c8fbb69f665b342ec7aff6
http://hdl.handle.net/11567/1021651

Blocking Tumor-Educated MSC Paracrine Activity Halts Osteosarcoma Progression

Autor: Anne-Marie Cleton-Jansen, Vincenzo Canzonieri, Monique A. J. van Eijndhoven, Laura Roncuzzi, Sulev Kõks, Tonny Lagerweij, Nicoletta Zini, Massimo Dominici, Maria Pérez-Lanzón, Roberta Bonafede, Tanja D. de Gruijl, Silvia Cervo, Aare Märtson, Nicolas Léveillé, D. Michiel Pegtel, Nicola Baldini, Thomas Wurdinger, Xuan Dung Ho, Agostino Steffan, Katre Maasalu, Ekaterina S. Jordanova, S. Rubina Baglio, Giulia Grisendi, M. Greco, Sonia A. Melo, Sinéad M. Lougheed

Publikováno v: Clinical Cancer Research, 23(14), 3721-3733. American Association for Cancer Research Inc.
Clinical cancer research, 23(14), 3721-3733. American Association for Cancer Research Inc.
Clinical Cancer Research, 23(14), 3721-3733
Baglio, S R, Lagerweij, T, Pérez-Lanzón, M, Ho, X D, Léveillé, N, Melo, S A, Cleton-Jansen, A M, Jordanova, E S, Roncuzzi, L, Greco, M, Van Eijndhoven, M A J, Grisendi, G, Dominici, M, Bonafede, R, Lougheed, S M, De Gruijl, T D, Zini, N, Cervo, S, Steffan, A, Canzonieri, V, Martson, A, Maasalu, K, Köks, S, Wurdinger, T, Baldini, N & Pegtel, D M 2017, ' Blocking tumor-educated MSC paracrine activity halts osteosarcoma progression ', Clinical Cancer Research, vol. 23, no. 14, pp. 3721-3733 . https://doi.org/10.1158/1078-0432.CCR-16-2726

Purpose: Human osteosarcoma is a genetically heterogeneous bone malignancy with poor prognosis despite the employment of aggressive chemotherapy regimens. Because druggable driver mutations have not been established, dissecting the interactions betwe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fc995d21f815df8513d6bb494316e5
https://hdl.handle.net/11368/2967826

Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism

Autor: Sharon DeMorrow, Brandon Cooper, Lorenza Rimassa, Cheryl Galindo, Darijana Horvat, Li Huang, Matthew A. Quinn, Matthew McMillin, Gabriel Frampton, Hae Yong Pae, Francesca Bernuzzi, Pietro Invernizzi

Publikováno v: Gut. 61:268-277

Background and objectives Cholangiocarcinoma is a devastating cancer of biliary origin with limited treatment options. The growth factor, progranulin, is overexpressed in a number of tumours. The study aims were to assess the expression of progranuli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aced780f78f88e8d1428b3dc6caf4f73
https://doi.org/10.1136/gutjnl-2011-300643

Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium

Autor: Paul G. Ince, Gabor G. Kovacs, Orso Bugiani, Efstratios Patsouris, Giorgio Giaccone, Nikolaos Kavantzas, Piero Parchi, Stephen M. Gentleman, Nenad Bogdanovic, Irina Alafuzoff, Wolfgang Roggendorf, James W. Ironside, Nathalie Streichenberger, Tibor Hortobágyi, Dietmar Rudolf Thal, Danielle Seilhean, David Meyronet, Thomas Arzberger, Tamas Revesz, Safa Al-Sarraj, Manuela Neumann, Tatjana Nilsson, Annemieke J.M. Rozemuller, Ellen Gelpi, Istvan Bodi, Andy King, Penelope Korkolopoulou, Manuel B. Graeber, Maria Pikkarainen, Camelia M. Monoranu, Hans A. Kretzschmar, Isidro Ferrer, Stephen B. Wharton

Publikováno v: Journal of neural transmission 122(7), 957-972 (2014). doi:10.1007/s00702-014-1304-1
Alafuzoff, I, Pikkarainen, M, Neumann, M, Arzberger, T, Al-Sarraj, S, Bodi, I, Bogdanovic, N, Bugiani, O, Ferrer, I, Gelpi, E, Gentleman, S, Giaccone, G, Graeber, M B, Hortobagyi, T, Ince, P G, Ironside, J W, Kavantzas, N, King, A, Korkolopoulou, P, Kovacs, G G, Meyronet, D, Monoranu, C, Nilsson, T, Parchi, P, Patsouris, E, Revesz, T, Roggendorf, W, Rozemuller, A J M, Seilhean, D, Streichenberger, N, Thal, D R, Wharton, S B & Kretzschmar, H 2015, ' Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium ', Journal of Neural Transmission, vol. 122, no. 7, pp. 957-972 . https://doi.org/10.1007/s00702-014-1304-1
Journal of Neural Transmission, 122(7), 957-972. Springer Verlag

The BrainNet Europe consortium assessed the reproducibility in the assignment of the type of frontotemporal lobar degeneration (FTLD) with TAR DNA-binding protein (TDP) 43 following current recommendations. The agreement rates were influenced by the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e65adb86b124cd936db50b7d3240f35
https://pub.dzne.de/record/138018

Gene expression changes in progression of cervical neoplasia revealed by microarray analysis of cervical neoplastic keratinocytes

Autor: Rotondo, John Charles, Bosi, Silvia, Bassi, C, Ferracin, M, Lanza, Giovanni, Gafa', Roberta, Magri, Eros, Selvatici, Rita, Torresani, S, Marci, Roberto, Garutti, P, Negrini, Massimo, Tognon, Mauro, Martini, Fernanda

To evaluate the gene expression changes involved in neoplastic progression of cervical intraepithelial neoplasia. Using microarray analysis, large-scale gene expression profile was carried out on HPV16-CIN2, HPV16-CIN3, and normal cervical keratinocy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::45e5cd2e66f94e608a90bbfe78ead441
http://hdl.handle.net/11585/588494