Repeated Injury Promotes Tracheobronchial Tissue Stem Cell Attrition

Autor: Saranga Wijeratne, Don Hayes, Moumita Ghosh, Alfahdah Alsudayri, Susan D. Reynolds, Barry R. Stripp, Zhang Hong Tan, Cynthia L Hill, Tendy Chiang, Gianni Carraro, John Mahoney, Scott W. Lallier

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 12, Pp 1696-1713 (2021)

Chronic lung disease has been attributed to stem cell aging and/or exhaustion. We investigated these mechanisms using mouse and human tracheobronchial tissue‐specific stem cells (TSC). In mouse, chromatin labeling and flow cytometry demonstrated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8823b91f5178d66d0051a8722b992919
https://doi.org/10.1002/sctm.21-0032

Type II collagen‐positive embryonic progenitors are the major contributors to spine and intervertebral disc development and repair

Autor: Shuying Yang, Shuting Yang, Xinhua Li, Ling Qin

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 10, Pp 1419-1432 (2021)

Basic mechanism of spine development is poorly understood. Type II collagen positive (Col2+) cells have been reported to encompass early mesenchymal progenitors that continue to become chondrocytes, osteoblasts, stromal cells, and adipocytes in long

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a411f3e784ba5a3c92125791bf06ca5
http://europepmc.org/articles/PMC8459639

Neural crest-derived mesenchymal progenitor cells enhance cranial allograft integration

Autor: Zulma Gazit, Wafa Tawackoli, Robert H. Baloh, Melodie F. Metzger, Angela Papalamprou, Juliane D. Glaeser, Samuel Eberlein, Tina Stefanovic, Trevor J. Nelson, Doron Cohn‐Schwartz, Shiran Ben-David, Dmitriy Sheyn, Khosrowdad Salehi, Robert K. Ryu, Kevin J. Kim, Hyun W. Bae, Yasaman Arabi, Phillip H. Behrens

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 797-809 (2021)

Replacement of lost cranial bone (partly mesodermal and partly neural crest‐derived) is challenging and includes the use of nonviable allografts. To revitalize allografts, bone marrow‐derived mesenchymal stromal cells (mesoderm‐derived BM‐MSC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c283eaec32281621329a270fefe6036
https://doi.org/10.1002/sctm.20-0364

Conjunctival reconstruction via enrichment of human conjunctival epithelial stem cells by p75 through the NGF‐p75‐SALL2 signaling axis

Autor: Junzhao Chen, Fei Yu, Qinke Yao, Hao Sun, Chenxi Yan, Nianxuan Wu, Yao Fu, Yang Lu

Publikováno v: Stem Cells Translational Medicine, Vol 9, Iss 11, Pp 1448-1461 (2020)
Stem Cells Translational Medicine

Severe conjunctival diseases can cause significant conjunctival scarring, which seriously limits eye movement and affects patients' vision. Conjunctival reconstruction remains challenging due to the lack of efficient methods for stem cells enrichment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b0d062b14b9d24cf7af1eb271556d3
https://doaj.org/article/de4b25dd56334ffd822cdccd51698d96

Sensory nerves in the spotlight of the stem cell niche

Autor: Alexander Birbrair, Thiago M. Cunha, Rodrigo R. Resende, Pedro H.D.M. Prazeres, Beatriz G S Rocha, Anderson Oropeza, Pedro A C Costa, Vasco Azevedo, Akiva Mintz, Walison N. Silva, Gabryella S P Santos, Caroline C. Picoli, Rodrigo A. da Silva, Alinne C. Costa

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 3, Pp 346-356 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Niches are specialized tissue microenvironments that control stem cells functioning. The bone marrow mesenchymal stem cell niche defines a location within the marrow in which mesenchymal stem cells are retained and produce new cells throughout life.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cbca69a3d5dbadd99f09aab09bb106
http://europepmc.org/articles/PMC7900586