Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tissa T. Manavalan"'
Autor:
Tissa T Manavalan, Yun Teng, Lacey M Litchfield, Penn Muluhngwi, Numan Al-Rayyan, Carolyn M Klinge
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62334 (2013)
The role of miRNAs in acquired endocrine-resistant breast cancer is not fully understood. One hallmark of tumor progression is epithelial-to-mesenchymal transition (EMT), characterized by a loss of cell adhesion resulting from reduced E-cadherin and
Externí odkaz:
https://doaj.org/article/4ced475495ef4cae8c1783ccb9b8ff6a
Publikováno v:
European Journal of Immunology. 47:880-891
Interleukin-1 receptor-associated kinase (IRAK) 4 mediates host defense against infections. As an active kinase, IRAK4 elicits full spectra of myeloid differentiation primary response protein (MyD) 88-dependent responses, while kinase-inactive IRAK4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::476900a7f3d87c1a707967cdc8d5d228
https://doi.org/10.1002/eji.201646641
https://doi.org/10.1002/eji.201646641
Autor:
Goutham Pattabiraman, Yanbao Xiong, Tissa T. Manavalan, Michael Murphy, I-Cheng Ho, Andrei E. Medvedev, Hui-Hsin Chang, Fu Qiu
Publikováno v:
Journal of Innate Immunity. 8:171-184
Endotoxin tolerance protects the host by limiting excessive 'cytokine storm' during sepsis, but compromises the ability to counteract infections in septic shock survivors. It reprograms Toll-like receptor (TLR) 4 responses by attenuating the expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032dcde3bd86f6b45f91fdc340b3acb3
https://doi.org/10.1159/000440838
https://doi.org/10.1159/000440838
Autor:
Tissa T. Manavalan, Yanbao Xiong, Michael B. Murphy, Andrei E. Medvedev, Goutham Pattabiraman, Fu Qiu
Publikováno v:
Journal of Leukocyte Biology. 98:963-974
Development of endotoxin tolerance in macrophages during sepsis reprograms Toll-like receptor 4 signaling to inhibit proinflammatory cytokines without suppressing anti-inflammatory and antimicrobial mediators and protects the host from excessive infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab71501d38410f6b9683959d63189499
https://doi.org/10.1189/jlb.2vma0515-229rr
https://doi.org/10.1189/jlb.2vma0515-229rr
Autor:
Alois Jungbauer, Chuan Hu, Yun Teng, Carolyn M. Klinge, Tissa T. Manavalan, Svjetlana Medjakovic
Publikováno v:
Toxicological Sciences. 131:71-83
Fenhexamid and fludioxonil are antifungal agents used in agricultural applications, which are present at measurable amounts in fruits and vegetables. Fenhexamid and fludioxonil showed endocrine disruptor activity as antiandrogens in an androgen recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c78af57d536732a25d221b7f4a3e571
https://doi.org/10.1093/toxsci/kfs290
https://doi.org/10.1093/toxsci/kfs290
Autor:
Tissa T. Manavalan
MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level by repressing translation or stimulating mRNA degradation. In this study, I tested the hypothesis that miRNAs are differentially expressed in antiestrogen-sensitive MCF-7 v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25d4c2461893af05462dc64977fcda06
https://doi.org/10.18297/etd/897
https://doi.org/10.18297/etd/897
Autor:
Tissa T. Manavalan, Paul A. Voziyan, Eugenia M. Yazlovitskaya, Alla V. Ivanova, Wendell G. Yarbrough
Publikováno v:
Cell Death & Disease
Mechanism of radiosensitivity of normal tissues, a key factor in determining the toxic side effects of cancer radiotherapy, is not fully understood. We recently demonstrated that deficiency of mitochondrial tumor suppressor, Fus1, increases radiosens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b643e519660240383ffe25ec7d771c
https://pubmed.ncbi.nlm.nih.gov/25695605
https://pubmed.ncbi.nlm.nih.gov/25695605
Autor:
Numan Al-Rayyan, Carolyn M. Klinge, Penn Muluhngwi, Tissa T. Manavalan, Lacey M. Litchfield, Yun Teng
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e62334 (2013)
PLoS ONE, Vol 8, Iss 4, p e62334 (2013)
Introduction The role of miRNAs in acquired endocrine-resistant breast cancer is not fully understood. One hallmark of tumor progression is epithelial-to-mesenchymal transition (EMT), characterized by a loss of cell adhesion resulting from reduced E-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b857d2c9de5bc9938bea87635765111
http://europepmc.org/articles/PMC3633860
http://europepmc.org/articles/PMC3633860
Autor:
Tissa T. Manavalan, Yun Teng, Theodore S. Kalbfleisch, Susmita Datta, Yong Li, Savitri Appana, Carolyn M. Klinge
Microarrays identified miRNAs differentially expressed and 4-hydroxytamoxifen (4-OHT) regulated in MCF-7 endocrine- sensitive versus resistant LY2 human breast cancer cells. 97 miRNAs were differentially expressed in MCF-7 versus LY2 cells. Opposite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3cc0c39206c4999f9f60e8735ef1f7
https://europepmc.org/articles/PMC3214732/
https://europepmc.org/articles/PMC3214732/