Functional and molecular insights into the role of Sae2 C-terminus in the activation of MRX endonuclease.

Autor: Colombo CV; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Casari E; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Gnugnoli M; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Corallo F; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Tisi R; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Longhese MP; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Nov 18. Date of Electronic Publication: 2024 Nov 18.

Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding.

Autor: Pizzul P; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Casari E; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Rinaldi C; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Gnugnoli M; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Mangiagalli M; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Tisi R; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy., Longhese MP; Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano - Bicocca, 20126 Milano, Italy.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Mar 21; Vol. 52 (5), pp. 2355-2371.

Novel pathological variants of NHP2 affect N-terminal domain flexibility, protein stability, H/ACA Ribonucleoprotein (RNP) complex formation and telomerase activity.

Autor: Maliński B; Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58185, Sweden., Vertemara J; Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca, Milan 20126, Italy., Faustini E; Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58185, Sweden., Ladenvall C; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala 90185, Sweden., Norberg A; Klinisk genetik, Norrlands Universitetssjukhus, Umeå 75185, Sweden., Zhang Y; Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58185, Sweden., von Castelmur E; Department of Physics, Chemistry and Biology, Linköping University, Linköping 58183, Sweden., Baliakas P; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala 90185, Sweden., Tisi R; Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca, Milan 20126, Italy., Cammenga J; Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58185, Sweden.; Department of Laboratory Medicine, Lund University, Lund 22184, Sweden., Lottersberger F; Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping 58185, Sweden.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2023 Sep 16; Vol. 32 (19), pp. 2901-2912.

The Ycx1 protein encoded by the yeast YDL206W gene plays a role in calcium and calcineurin signaling.

Autor: Lee GM; Department of Biology, Saint Louis University, St Louis, Missouri, USA., Weng F; Department of Biology, Saint Louis University, St Louis, Missouri, USA., Cranley J; Department of Biology, Saint Louis University, St Louis, Missouri, USA., Rajasekhar A; Department of Biology, Saint Louis University, St Louis, Missouri, USA., Stoeckel M; Department of Biology, Saint Louis University, St Louis, Missouri, USA., Kane T; Department of Biology, Saint Louis University, St Louis, Missouri, USA., Tisi R; Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy., Wang Y; Department of Biology, Saint Louis University, St Louis, Missouri, USA. Electronic address: yuqi.wang@slu.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 May; Vol. 299 (5), pp. 104647. Date of Electronic Publication: 2023 Mar 24.

Natural compounds in cancer prevention: effects of coffee extracts and their main polyphenolic component 5-CQA on oncogenic Ras proteins

Autor: Palmioli, A, Ciaramelli, C, Tisi, R, Spinelli, M, De Sanctis, G, Sacco, E, Airoldi, C

Recent epidemiological studies have demonstrated that the consumption of healthy foods that are particularly rich in polyphenols might reduce the incidence of cancer and neurodegenerative diseases. In particular, chlorogenic acids (CGAs) occur ubiqui

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1299::aa203afff03f212490f380b399692745
http://hdl.handle.net/10281/161161