Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tirzah J. Weiss"'
Autor:
Brandon M. Murphy, Elizabeth M. Terrell, Venkat R. Chirasani, Tirzah J. Weiss, Rachel E. Lew, Andrea M. Holderbaum, Aastha Dhakal, Valentina Posada, Marie Fort, Michael S. Bodnar, Leiah M. Carey, Min Chen, Craig J. Burd, Vincenzo Coppola, Deborah K. Morrison, Sharon L. Campbell, Christin E. Burd
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The factors that determine the distinct profiles of NRAS mutants across different tumor types remain unclear. Here, the authors use an allelic series of conditional mouse models to investigate the molecular mechanisms underlying the enrichment of spe
Externí odkaz:
https://doaj.org/article/a16f75dc242345688e57e18ad40b740a
Autor:
Tirzah J. Weiss, Emma R. Crawford, Valentina Posada, Hafeez Rahman, Tong Liu, Brandon M. Murphy, Tiffany E. Arnold, Shannon Gray, Zhexuan Hu, Rebecca C. Hennessey, Lianbo Yu, John A. D'Orazio, Craig J. Burd, Jonathan H. Zippin, Douglas Grossman, Christin E. Burd
Publikováno v:
Pigment cellmelanoma researchREFERENCES. 36(1)
Melanin is a free-radical scavenger, antioxidant, and broadband absorber of ultraviolet (UV) radiation which protects the skin from environmental carcinogenesis. However, melanin synthesis and UV-induced reactive melanin species are also implicated i
Autor:
Ross L. Levine, Robert L. Bowman, Brandon M. Murphy, Amy Webb, A. Hunter Shain, Christin E. Burd, Tirzah J Weiss, Souhui Zhang, Craig J. Burd, David Tallman, Rebecca C. Hennessey, Emma R. Crawford, Krista M. D. La Perle
Publikováno v:
Life Science Alliance
A single, neonatal UVB exposure drives greater UV-signature production in Braf- than Nras-mutant murine melanomas.
BRAF-mutant melanomas are more likely than NRAS-mutant melanomas to arise in anatomical locations protected from chronic sun damag
BRAF-mutant melanomas are more likely than NRAS-mutant melanomas to arise in anatomical locations protected from chronic sun damag
Autor:
Michael S Bodnar, Tirzah J Weiss, Min Chen, Craig J. Burd, Vincenzo Coppola, Andrea M. Holderbaum, Marie Fort, Christin E. Burd, Brandon M. Murphy, Aastha Dhakal
Distinct NRAS mutants are enriched in various tumor types. Here, we generated a suite of fully congenic, conditional, Nras knock-in mouse models (LSL-Nras Q61R, -K, -L, -H, -P, -Q; G12D and G13D, -R) to test the hypothesis that melanocyte transformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89966cd9c0b92ed576aeed123a7b5fa2
https://doi.org/10.1101/2021.01.15.426808
https://doi.org/10.1101/2021.01.15.426808
Autor:
Tirzah J Weiss, Sung Ok Yoon, Youko Ikeda, Mitsuharu Yoshiyama, Stephanie L. Daugherty, Anastasia Soulas, Anthony Kanai, Nabila Saidi, Susan E. Malley, Nisha Ganesh, Uri H. Saragovi, Irina Zabbarova, William C. de Groat, Margaret A. Vizzard, Jae Cheon Ryu, Katharine Tooke, H. Francis Farhadi
Publikováno v:
Journal of Clinical Investigation. 128:1772-1786
Loss of bladder control is a challenging outcome facing patients with spinal cord injury (SCI). We report that systemic blocking of pro–nerve growth factor (proNGF) signaling through p75 with a CNS-penetrating small-molecule p75 inhibitor resulted
Publikováno v:
J Vis Exp
Defects in fibroblast or melanocyte function are associated with skin diseases, including poor barrier function, defective wound healing, pigmentation defects and cancer. Vital to the understanding and amelioration of these diseases are experiments i