Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tirumalai R. Raghunand"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101672- (2024)
Autophagy has emerged as a critical innate immune mechanism for host elimination of intracellular pathogens, however, the role of the autophagy receptor Optineurin during mycobacterial infection is not fully understood. To address this lacuna, we inf
Externí odkaz:
https://doaj.org/article/06c3ba4c4e5a419ab08b3463e66f0c20
Mycobacterium tuberculosis (M. tb)the causative agent of human tuberculosis, is one of the most successful pathogens known to man. The key to its success is the multiple factors it encodes to subvert host immune responses. One such class of virulence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bcde8a2ea3838ab0904ff7af1cda14a
https://doi.org/10.1101/2023.04.07.535983
https://doi.org/10.1101/2023.04.07.535983
Autor:
Mamata Savanagouder, Ravi Prasad Mukku, Uday Kiran, Chaitanya Veena Yeruva, Nandhini Nagarajan, Yogendra Sharma, Tirumalai R. Raghunand
Mycobacterium tuberculosis (M. tb)has a complex cell wall, largely composed of mycolic acids and long-chain fatty acids that play a crucial role in maintaining its integrity and permeability. This complex lipid structure has a role in abrogating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b6c920a87de2ed941c6a09a4f9f79f6
https://doi.org/10.1101/2023.03.31.535087
https://doi.org/10.1101/2023.03.31.535087
The extraordinary success ofMycobacterium tuberculosis(M. tb) has been attributed to its ability to modulate host immune responses. The genome ofM. tbencodes multiple immunomodulatory factors, including several proteins of the multigenic PE_PPE famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a70bf2643f05f693fcfe710b0bf0532
https://doi.org/10.1101/2023.03.30.534876
https://doi.org/10.1101/2023.03.30.534876
A major virulence trait ofMycobacterium tuberculosis(M. tb) is its ability to enter a dormant state within its human host. Since cell division is intimately linked to metabolic shut down, understanding the mechanism of septum formation and its integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c422bed99fa875cbc45a8f58db671f
https://doi.org/10.1101/2023.03.20.533423
https://doi.org/10.1101/2023.03.20.533423
Publikováno v:
Biochemical and Biophysical Research Communications. 534:297-302
We have investigated the physiological role of the autophagy receptor Optineurin/Optn in endoplasmic reticulum (ER) stress response using cellular and animal models. In comparison to their normal counterparts, Optn-deficient mouse embryonic fibroblas
Autor:
Aritri Dutta, Ravi Prasad Mukku, G. Aditya Kumar, Md. Jafurulla, Tirumalai R. Raghunand, Amitabha Chattopadhyay
Publikováno v:
The Journal of membrane biology. 255(4-5)
Macrophages are the primary hosts for Mycobacterium tuberculosis (M. tb), an intracellular pathogen, and the causative organism of tuberculosis (TB) in humans. While M. tb has the ability to enter and survive in host macrophages, the precise mechanis
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51686 (2012)
The unique PE/PPE multigene family of proteins occupies almost 10% of the coding sequence of Mycobacterium tuberculosis (M.tb), the causative agent of human tuberculosis. Although some members of this family have been shown to be involved in pathways
Externí odkaz:
https://doaj.org/article/dbd311a07b7a4fd0841c18aad04fc5e9
Autor:
G. Aditya Kumar, Amitabha Chattopadhyay, Md. Jafurulla, Tirumalai R. Raghunand, Gopinath Viswanathan
Publikováno v:
Chemistry and Physics of Lipids. 213:25-31
Mycobacteria are intracellular pathogens that can invade and survive within host macrophages. Mycobacterial infections remain a major cause of mortality and morbidity worldwide, with serious concerns of emergence of multi and extensively drug-resista
Autor:
Tirumalai R. Raghunand, Veena C. Yeruva, Mamata Savanagouder, Apoorva Kulkarni, Yogendra Sharma, Radhika Khandelwal
Publikováno v:
Biochemical and Biophysical Research Communications. 480:29-35
The hallmark feature of Mycobacterium tuberculosis (M.tb) the causative agent of human tuberculosis, is its complex lipid rich cell wall comprised primarily of mycolic acids, long chain fatty acids that play a key role in structural stability and per