Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Tirthankar, Mohanty"'
Autor:
Erik Hartman, Aaron M. Scott, Christofer Karlsson, Tirthankar Mohanty, Suvi T. Vaara, Adam Linder, Lars Malmström, Johan Malmström
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The incorporation of machine learning methods into proteomics workflows improves the identification of disease-relevant biomarkers and biological pathways. However, machine learning models, such as deep neural networks, typically suffer from
Externí odkaz:
https://doaj.org/article/6ba2704448034c108462da0c1d21a25d
Autor:
Tirthankar Mohanty, Christofer A. Q. Karlsson, Yashuan Chao, Erik Malmström, Eleni Bratanis, Andrietta Grentzmann, Martina Mørch, Victor Nizet, Lars Malmström, Adam Linder, Oonagh Shannon, Johan Malmström
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Sepsis is the major cause of mortality across intensive care units globally, yet details of accompanying pathological molecular events remain unclear. This knowledge gap has resulted in ineffective biomarker development and suboptimal treatm
Externí odkaz:
https://doaj.org/article/5bac18b01da14d49bb234886c176c6ba
Autor:
Aaron M. Scott, Christofer Karlsson, Tirthankar Mohanty, Erik Hartman, Suvi T. Vaara, Adam Linder, Johan Malmström, Lars Malmström
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Data independent acquisition mass spectrometry (DIA-MS) has recently emerged as an important method for the identification of blood-based biomarkers. However, the large search space required to identify novel biomarkers from the plasma prote
Externí odkaz:
https://doaj.org/article/c62f01db96f746e9960e9d6a3d365a00
Autor:
Tirthankar Mohanty, Jane Fisher, Anahita Bakochi, Ariane Neumann, José Francisco Pereira Cardoso, Christofer A. Q. Karlsson, Chiara Pavan, Iben Lundgaard, Bo Nilson, Peter Reinstrup, Johan Bonnevier, David Cederberg, Johan Malmström, Peter Bentzer, Adam Linder
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Neutrophils play critical roles in the host response to bacteria, including the production neutrophil extracellular traps (NET). Here the authors show that NET formation in the context of pneumococcal meningitis impairs bacterial clearance and target
Externí odkaz:
https://doaj.org/article/b07c86bc32944286b1715bc59d4fafda
Autor:
Anahita Bakochi, Tirthankar Mohanty, Paul Theodor Pyl, Carlos Alberto Gueto-Tettay, Lars Malmström, Adam Linder, Johan Malmström
Publikováno v:
eLife, Vol 10 (2021)
Meningitis is a potentially life-threatening infection characterized by the inflammation of the leptomeningeal membranes. Many different viral and bacterial pathogens can cause meningitis, with differences in mortality rates, risk of developing neuro
Externí odkaz:
https://doaj.org/article/9e8ee4bfe6b748d8afb5af3fcf75f342
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Neutrophil extracellular traps (NETs) that are extensive webs of DNA covered with antimicrobial proteins into the extracellular environment during infection or inflammation as a part of their defense arsenal. Image acquisition of fluorescently labele
Externí odkaz:
https://doaj.org/article/58c6194d134440f3ade54638abd97111
Autor:
Aaron M. Scott, Christofer Karlsson, Tirthankar Mohanty, Suvi T. Vaara, Adam Linder, Johan Malmström, Lars Malmström
The statistical validation of peptide and protein identifications in mass spectrometry proteomics is a critical step in the analytical workflow. This is particularly important in discovery experiments to ensure only confident identifications are accu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3a3dd24cd8fff6b634e1fe5f502e045
https://doi.org/10.1101/2022.11.03.515031
https://doi.org/10.1101/2022.11.03.515031
Autor:
Tirthankar Mohanty, Christofer A. Q. Karlsson, Yashuan Chao, Erik Malmström, Eleni Bratanis, Andrietta Grentzmann, Martina Mørch, Victor Nizet, Lars Malmström, Adam Linder, Oonagh Shannon, Johan Malmström
Sepsis is the major cause of mortality across intensive care units globally, yet details of accompanying pathological molecular events remains unclear. This knowledge gap has resulted in ineffective development of sepsis-specific biomarkers and thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52dd06f0ed7e87c23704e18f6f34ab09
https://doi.org/10.1101/2022.08.29.503941
https://doi.org/10.1101/2022.08.29.503941
Autor:
Thomas Helleday, Jonas S. Erjefält, Christina Kalderén, Olov A. Wallner, Christoffer Karlsson, Ravi K. V. Bhongir, Lloyd Tanner, Moritz Heusel, Arne Egesten, Tirthankar Mohanty, Carl-Magnus Clausson, A.B. Single, Cecilia Andersson, Johan Malmström, Riya Oommen
Interstitial lung diseases such as idiopathic pulmonary fibrosis (IPF) are caused by persistent micro-injuries to alveolar epithelial tissues accompanied by aberrant repair processes. Despite substantial advancement in our understanding of IPF progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffb3ae8ddef71a607bec4eaf9262b30c
https://doi.org/10.21203/rs.3.rs-990197/v1
https://doi.org/10.21203/rs.3.rs-990197/v1
Autor:
Andreas, Forsvall, Jane, Fisher, José Francisco Pereira, Cardoso, Magnus, Wagenius, Jonas, Tverring, Bo, Nilson, Andreas, Dahlin, Ola, Bratt, Adam, Linder, Tirthankar, Mohanty
Publikováno v:
Scandinavian journal of urology. 55(3)
Transrectal prostate biopsy (TRbx) transfers colonic bacteria into prostatic tissue, potentially causing infectious complications, including sepsis. Our objective was to determine whether biopsy needle shape, surface properties and sampling mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ef75c40edda407023ea9661f0488924
https://pubmed.ncbi.nlm.nih.gov/33999753
https://pubmed.ncbi.nlm.nih.gov/33999753