Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tiroyaone M. Brombacher"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
C57BL/6 mice are one of the most widely used inbred strains in biomedical research. Early separation of the breeding colony has led to the development of several sub-strains. Colony separation led to genetic variation development driving numerous phe
Externí odkaz:
https://doaj.org/article/f010e2c6c96544c6a552334f63c9fde1
Autor:
Duyilemi Chris Ajonijebu, Thabo Mpotje, B.O. Moses, Inssaf Berkiks, Frank Brombacher, M. Scibiorek, Tiroyaone M Brombacher
Publikováno v:
Brain, Behavior, and Immunity
Contribution of immune mediators, interleukin-4 and interferon gamma to cognitive functioning is receiving increasing attention. However, the fundamental question about how heterodimeric interleukin-4 receptor alpha– and interferon gamma– produci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b7133482da919ed0f2601d5197408a
http://europepmc.org/articles/PMC7909383
http://europepmc.org/articles/PMC7909383
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Like pro-inflammatory cytokines, the role of anti-inflammatory cytokines in both learning and memory has been investigated, revealing beneficial effects for both interleukin-4 and interleukin-13 via the common interleukin-4 receptor alpha chain compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10775353859fa829cec5135590940e71
https://doi.org/10.1038/s41598-020-73574-3
https://doi.org/10.1038/s41598-020-73574-3
Autor:
Saskia Schmidt, J Claire Hoving, William G C Horsnell, Helen Mearns, Antony J Cutler, Tiroyaone M Brombacher, Frank Brombacher
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52211 (2012)
Gut-dwelling helminthes induce potent IL-4 and IL-13 dominated type 2 T helper cell (T(H)2) immune responses, with IL-13 production being essential for Nippostrongylus brasiliensis expulsion. This T(H)2 response results in intestinal inflammation ass
Externí odkaz:
https://doaj.org/article/0ee86013cbaf46e4a110b53ddfe17641
Autor:
Keisha S De Gouveia, Jacqueline S. Womersley, Ousman Tamgue, Tiroyaone M Brombacher, Nokuthula Makena, Frank Brombacher, Matthew Darby, Justin Komguep Nono
Publikováno v:
The Journal of Immunology. 198:2681-2688
The role of proinflammatory cytokines in cognitive function has been investigated with both beneficial and possible detrimental effects, depending on the cytokine. More recently, the type 2 IL-4 has been demonstrated to play a role in cognition. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995cdaccb746e053965658822ccd1edf
https://doi.org/10.4049/jimmunol.1601546
https://doi.org/10.4049/jimmunol.1601546
Autor:
L. Cruywagen, Ousman Tamgue, F. Booley, Frank Brombacher, K. S. De Gouveia, Tiroyaone M Brombacher, Nokuthula Makena
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Hookworm infection is endemic in developing countries, leading to poor cognitive function—among other disruptions. In this study, the effects of Nippostrongylus brasiliensis infection (a murine model of Necator Americanus) on cognitive function wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa6734181e5fe7649f3aeaa4985af9b
http://europepmc.org/articles/PMC5811425
http://europepmc.org/articles/PMC5811425
Autor:
Tiroyaone M Brombacher, Frank Brombacher, Lauriston Kellaway, Benjamin G Dewals, Dhirendra Govender, Reece Gerrad Marillier, William Gc Horsnell, Mark Barkhuizen, Mosiuoa Leeto
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 298:G943-G951
Interleukin-(IL)-4 and IL-13 signal through heterodimeric receptors containing a common IL-4 receptor-α (IL-4Rα) subunit, which is important for protection against helminth infections, including schistosomiasis. Previous studies demonstrated import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ce2b5c42c2a9309c59cc51923987a8
https://doi.org/10.1152/ajpgi.00321.2009
https://doi.org/10.1152/ajpgi.00321.2009